Search Results - "Britcher, Susan F"

Synthesis and pharmacological evaluation of a series of dibenzo[a,d]cycloalkenimines as N-methyl-D-aspartate antagonists by Thompson, Wayne J, Anderson, Paul S, Britcher, Susan F, Lyle, Terry A, Thies, J. Eric, Magill, Catherine A, Varga, Sandor L, Schwering, John E, Lyle, Paulette A

“…A series of 73 dibenzo[a,d]cycloalkenimines were synthesized and evaluated for their ability to displace…”
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Synthesis of a Series of 4-(Arylethynyl)-6-chloro-4-cyclopropyl-3,4-dihydroquinazolin-2(1H)-ones as Novel Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors by Tucker, Thomas J, Lyle, Terry A, Wiscount, Catherine M, Britcher, Susan F, Young, Steven D, Sanders, William M, Lumma, William C, Goldman, Mark E, O'Brien, Julie A

“…As part of an ongoing effort to prepare novel non-nucleoside inhibitors of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT), a series of…”
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Inhibitors of gastric acid secretion: 3,4-diamino-1,2,5-thiadiazole 1-oxides and 1,1-dioxides as urea equivalents in a series of histamine H2 receptor antagonists by Lumma, William C, Anderson, Paul S, Baldwin, John J, Bolhofer, William A, Britcher, Susan F, Clineschmidt, Bradley V, Denny, George H, Habecker, Charles N, Hirshfield, Jordan M

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Synthesis of 2-, 3- and 9-substituted 11-oxo-11H-pyrrolo[2,1-b][3]benzazepines by Belanger, Patrice C, Atkinson, Joseph G, Rooney, C. Stanley, Britcher, Susan F, Remy, David C

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Synthesis and receptor binding studies relevant to the neuroleptic activities of some 1-methyl-4-piperidylidene-9-substituted-pyrrolo[2,1-b][3]benzazepine derivatives by Remy, David C, Britcher, Susan F, King, Stella W, Anderson, Paul S, Hunt, Cecilia A, Randall, William C, Belanger, Patrice, Atkinson, Joseph G, Girard, Yves

“…The synthesis of a series of 1-methyl-4-(9-substituted-11H-pyrrolo[2,1-b]benzazepin-11-ylidene)piperidines (4a-f) and…”
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Transannular reactions of dibenzo[a,d]cycloalkenes. 1. Synthesis of dibenzo[a,d]cycloocten-6,12-imines and dibenzo[a,d]cyclohepten-5,10-imines by Christy, Marcia E, Anderson, Paul S, Britcher, Susan F, Colton, C. Dylion, Evans, Ben E, Remy, David C, Engelhardt, Edward L

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HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: An investigation into the role of the P1' side chain on structure-activity by Young, Steven D, Payne, Linda S, Thompson, Wayne J, Gaffin, Neil, Lyle, Terry A, Britcher, Susan F, Graham, Samuel L, Schultz, Thomas H, Deana, Albert A

“…A systematic investigation was undertaken to determine the role of the P1' sidechain in a series of hydroxyethylene isostere based inhibitors of HIV-1…”
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Construction of the taxane C-ring epoxy alcohol moiety and examination of its possible involvement in the biogenesis of the taxane 3-oxetanol structure by Swindell, Charles S, Britcher, Susan F

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Structure and activity of hydrogenated derivatives of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801) by Lyle, Terry A, Magill, Catherine A, Britcher, Susan F, Denny, George H, Thompson, Wayne J, Murphy, Joan S, Knight, Antony R, Kemp, John A, Marshall, George R

“…Several hydrogenated derivatives of the potent NMDA antagonist 1 have been prepared and evaluated as competitive inhibitors of [3H]-1 binding. These compounds…”
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Direct synthesis of trisubstituted isothiazole 1,1-dioxides. Regioselective substitution reactions at C-3 and C-4 by Britcher, Susan F, Cochran, David W, Phillips, Brian T, Springer, James P, Lumma, William C

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Synthesis and orexigenic activity of some 1-methyl-4-piperidylidene-substituted pyrrolo[2,1-b][3]benzazepine and dibenzocycloheptene derivatives by Remy, David C, Britcher, Susan F, Anderson, Paul S, Belanger, Patrice C, Girard, Yves, Clineschmidt, B. V

“…The synthesis and orexigenic activity of some unsubstituted and Bz-carboxylic acid substituted 1-methyl-4-piperidylidenepyrrolo[2,1-b][3]benzazepine and…”
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Bridged bicyclic and polycyclic amino acids. Potent new inhibitors of the fibrinolytic process by Loeffler, Larry J, Britcher, Susan F, Baumgarten, Werner

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Tyrosine Hydroxylase Inhibitors. Synthesis and Activity of Substituted Aromatic Amino Acids by Saari, Walfred S, Williams, June, Britcher, Susan F, Wolf, Donald E, Kuehl, Frederick A

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2-Heterocyclic indole-3-sulfones as inhibitors of HIV-1 reverse transcriptase by Young, Steven D., Amblard, Muriel C., Britcher, Susan F., Grey, Vanessa E., Tran, Lee O., Lumma, William C., Huff, Joel R., Schleif, William A., Emini, Emilio E., O'Brien, Julie A., Pettibone, Douglas J.

“…A variety of 2-heterocycle substituted 3-phenysulfonyl-5-chloroindoles were investigated as replacements for the 2-carboxamide functionality of the potent…”
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