Search Results - "Britain, Colleen M"

ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor by Holdbrooks, Andrew T., Britain, Colleen M., Bellis, Susan L.

“…Activation of the tumor necrosis factor receptor 1 (TNFR1) death receptor by TNF induces either cell survival or cell death. However, the mechanisms mediating…”
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Transfer of Functional Cargo in Exomeres by Zhang, Qin, Higginbotham, James N., Jeppesen, Dennis K., Yang, Yu-Ping, Li, Wei, McKinley, Eliot T., Graves-Deal, Ramona, Ping, Jie, Britain, Colleen M., Dorsett, Kaitlyn A., Hartman, Celine L., Ford, David A., Allen, Ryan M., Vickers, Kasey C., Liu, Qi, Franklin, Jeffrey L., Bellis, Susan L., Coffey, Robert J.

“…Exomeres are a recently discovered type of extracellular nanoparticle with no known biological function. Herein, we describe a simple ultracentrifugation-based…”
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The Glycosyltransferase ST6Gal-I Protects Tumor Cells against Serum Growth Factor Withdrawal by Enhancing Survival Signaling and Proliferative Potential by Britain, Colleen M., Dorsett, Kaitlyn A., Bellis, Susan L.

“…A hallmark of cancer cells is the ability to survive and proliferate when challenged with stressors such as growth factor insufficiency. In this study, we…”
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Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death by Britain, Colleen M, Holdbrooks, Andrew T, Anderson, Joshua C, Willey, Christopher D, Bellis, Susan L

“…The ST6Gal-I sialyltransferase is upregulated in numerous cancers, and high expression of this enzyme correlates with poor patient prognosis in various…”
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ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression by Bhalerao, Nikita, Chakraborty, Asmi, Marciel, Michael P, Hwang, Jihye, Britain, Colleen M, Silva, Austin D, Eltoum, Isam E, Jones, Robert B, Alexander, Katie L, Smythies, Lesley E, Smith, Phillip D, Crossman, David K, Crowley, Michael R, Shin, Boyoung, Harrington, Laurie E, Yan, Zhaoqi, Bethea, Maigen M, Hunter, Chad S, Klug, Christopher A, Buchsbaum, Donald J, Bellis, Susan L

“…The role of aberrant glycosylation in pancreatic ductal adenocarcinoma (PDAC) remains an under-investigated area of research. In this study, we determined that…”
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Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells by Britain, Colleen M., Bhalerao, Nikita, Silva, Austin D., Chakraborty, Asmi, Buchsbaum, Donald J., Crowley, Michael R., Crossman, David K., Edwards, Yvonne J.K., Bellis, Susan L.

“…ST6Gal-I, an enzyme upregulated in numerous malignancies, adds α2-6-linked sialic acids to select membrane receptors, thereby modulating receptor signaling and…”
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Role of the ST6GAL1 sialyltransferase in regulating ovarian cancer cell metabolism by Jones, Robert B, Silva, Austin D, Ankenbauer, Katherine E, Britain, Colleen M, Chakraborty, Asmi, Brown, Jamelle A, Ballinger, Scott W, Bellis, Susan L

“…Abstract The ST6GAL1 sialyltransferase, which adds α2–6-linked sialic acids to N-glycosylated proteins, is upregulated in many malignancies including ovarian…”
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Receptor Sialylation by ST6Gal-I Promotes Tumor Progression by Enhancing Tumor Cell Survival and Epithelial to Mesenchymal Transition by Britain, Colleen M

“…The upregulation of a certain subset of glycosyltransferases was an early marker for cancer development. Specifically, ST6Gal-I, which adds an α2-6 linked…”
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Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells by Britain, Colleen M, Bhalerao, Nikita, Silva, Austin D, Chakraborty, Asmi, Buchsbaum, Donald J, Crowley, Michael R, Crossman, David K, Edwards, Yvonne J K, Bellis, Susan L

“…ST6Gal-I, an enzyme upregulated in numerous malignancies, adds α2-6-linked sialic acids to select membrane receptors, thereby modulating receptor signaling and…”
Get full text