Search Results - "Bristot, Ivi Juliana"
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Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas
Published in Cancer letters (28-03-2015)“…Abstract Glioblastoma is a devastating primary brain tumor resistant to conventional therapies. In this study, we tested the efficacy of combining temozolomide…”
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Effects of chronic caloric restriction on kidney and heart redox status and antioxidant enzyme activities in Wistar rats
Published in BMB reports (30-11-2012)“…Caloric restriction (CR) has been associated with health benefits and these effects have been attributed, in part, to modulation of oxidative status by CR;…”
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Cannabidiol Exposure During Neuronal Differentiation Sensitizes Cells Against Redox-Active Neurotoxins
Published in Molecular neurobiology (01-08-2015)“…Cannabidiol (CBD), one of the most abundant Cannabis sativa -derived compounds, has been implicated with neuroprotective effect in several human pathologies…”
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4
Cofilin/actin rod formation by dysregulation of cofilin-1 activity as a central initial step in neurodegeneration
Published in Mini reviews in medicinal chemistry (01-05-2014)“…Cofilin-1 protein, which main function is to regulate actin cytoskeleton dynamics, appears to be involved with many steps in the neurotoxicity processes found…”
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5
Effects of chronic caloric restriction on kidney and heart redox status and antioxidant enzyme activities in Wistar rats
Published in BMB reports (01-11-2012)“…Caloric restriction (CR) has been associated with health benefits and these effects have been attributed, in part, to modulation of oxidative status by CR;…”
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6
Metabolic rewiring in melanoma drug-resistant cells
Published in Critical reviews in oncology/hematology (01-09-2020)“…•Melanoma can shift its metabolic phenotype in response to different forms of treatment that can lead to metastatic outcomes•Expression levels of JARID1B and…”
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Cannabinoid-Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System
Published in CNS drugs (01-08-2018)“…The endocannabinoid retrograde signaling pathway is widely expressed in the central nervous system, where it plays major roles in regulating synaptic…”
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8
Systematic screening of synthetic organochalcogen compounds with anticancer activity using human lung adenocarcinoma spheroids
Published in Chemico-biological interactions (01-06-2024)“…Lung adenocarcinoma stands as a leading global cause of cancer-related fatalities, with current therapeutic approaches remaining unsatisfactory. Given the…”
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Mimicking Parkinson’s Disease in a Dish: Merits and Pitfalls of the Most Commonly used Dopaminergic In Vitro Models
Published in Neuromolecular medicine (01-09-2017)“…Parkinson’s disease (PD) is the second most common neurodegenerative disorder and has both unknown etiology and non-curative therapeutic options. Patients…”
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10
Immunosenescence Induced by Plasma from Individuals with Obesity Caused Cell Signaling Dysfunction and Inflammation
Published in Obesity (Silver Spring, Md.) (01-09-2017)“…Objective To evaluate the consequences of plasma from individuals with obesity on parameters associated with immunosenescence in unrelated healthy peripheral…”
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11
Cannabinoid.Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System
Published in CNS drugs (01-08-2018)“…The endocannabinoid retrograde signaling pathway is widely expressed in the central nervous system, where it plays major roles in regulating synaptic…”
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12
Sertraline reduces glutamate uptake in human platelets
Published in Neurotoxicology (Park Forest South) (01-12-2015)“…•Cell viability and ATP levels are not affected by sertraline at therapeutic levels.•Sertraline in the low micromolar range decreases glutamate…”
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Phenylalanine induces oxidative stress and decreases the viability of rat astrocytes: possible relevance for the pathophysiology of neurodegeneration in phenylketonuria
Published in Metabolic brain disease (01-06-2016)“…The aim of this study was to investigate the effects of phenylalanine on oxidative stress and some metabolic parameters in astrocyte cultures from newborn…”
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In vitro optimization of retinoic acid–induced neuritogenesis and TH endogenous expression in human SH-SY5Y neuroblastoma cells by the antioxidant Trolox
Published in Molecular and cellular biochemistry (01-12-2011)“…Though, it is quite well-known how retinoic acid (RA) is able to induce neuritogenesis in different in vitro models, the putative role exerted by reactive…”
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