Search Results - "Bristol, A."
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ΔNp63α promotes Epstein-Barr virus latency in undifferentiated epithelial cells
Published in PLoS pathogens (01-11-2021)“…Epstein-Barr virus (EBV) is a human herpesvirus that causes infectious mononucleosis and contributes to both B-cell and epithelial-cell malignancies…”
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2
A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection
Published in PLoS pathogens (27-07-2018)“…Latent Epstein-Barr virus (EBV) infection contributes to both B-cell and epithelial-cell malignancies. However, whether lytic EBV infection also contributes to…”
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3
Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells
Published in PLoS pathogens (01-04-2022)“…Humans are infected with two types of EBV (Type 1 (T1) and Type 2 (T2)) that differ substantially in their EBNA2 and EBNA 3A/B/C latency proteins and have…”
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4
Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells
Published in PLoS pathogens (02-08-2021)“…The Epstein-Barr virus (EBV) human herpesvirus is associated with B-cell and epithelial-cell malignancies, and both the latent and lytic forms of viral…”
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5
Latent Epstein-Barr virus infection collaborates with Myc over-expression in normal human B cells to induce Burkitt-like Lymphomas in mice
Published in PLoS pathogens (01-04-2024)“…Epstein-Barr virus (EBV) is an important cause of human lymphomas, including Burkitt lymphoma (BL). EBV+ BLs are driven by Myc translocation and have stringent…”
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6
EBNA2-deleted Epstein-Barr virus (EBV) isolate, P3HR1, causes Hodgkin-like lymphomas and diffuse large B cell lymphomas with type II and Wp-restricted latency types in humanized mice
Published in PLoS pathogens (01-06-2020)“…EBV transforms B cells in vitro and causes human B-cell lymphomas including classical Hodgkin lymphoma (CHL), Burkitt lymphoma (BL) and diffuse large B-cell…”
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7
B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection
Published in PLoS pathogens (01-02-2020)“…Humans are infected with two distinct strains (Type 1 (T1) and Type 2 (T2)) of Epstein-Barr virus (EBV) that differ substantially in their EBNA2 and EBNA…”
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8
Type 1 and Type 2 Epstein-Barr viruses induce proliferation, and inhibit differentiation, in infected telomerase-immortalized normal oral keratinocytes
Published in PLoS pathogens (01-10-2022)“…Differentiated epithelial cells are an important source of infectious EBV virions in human saliva, and latent Epstein-Barr virus (EBV) infection is strongly…”
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9
Perceptions about health-risk awareness and lifestyle change among women at risk for developing cardiometabolic disease: a qualitative study
Published in Discover social science and health (01-12-2024)“…Background The reproductive years provide a window into future risk for Type 2 Diabetes (T2DM); women’s risk is seven to 10 times higher after gestational…”
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10
An EBNA3C-deleted Epstein-Barr virus (EBV) mutant causes B-cell lymphomas with delayed onset in a cord blood-humanized mouse model
Published in PLoS pathogens (01-08-2018)“…EBV causes human B-cell lymphomas and transforms B cells in vitro. EBNA3C, an EBV protein expressed in latently-infected cells, is required for EBV…”
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11
Tailoring of Health-Promotion Video Messaging for Reproductive-Aged Women at Risk for Developing Cardiometabolic Disease: Qualitative Focus-Groups Study
Published in JMIR formative research (05-03-2024)“…Targeting reproductive-aged women at high risk for type 2 diabetes (T2D) provides an opportunity for prevention earlier in the life course. A woman's…”
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12
Hsp90 Inhibitor 17-DMAG Decreases Expression of Conserved Herpesvirus Protein Kinases and Reduces Virus Production in Epstein-Barr Virus-Infected Cells
Published in Journal of Virology (01-09-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
Using Continuous Glucose Monitoring and Data Sharing to Encourage Collaboration Among Older Adults With Type 1 Diabetes and Their Care Partners: Qualitative Descriptive Study
Published in JMIR nursing (26-07-2023)“…Persons with diabetes use continuous glucose monitoring (CGM) to self-manage their diabetes. Care partners (CPs) frequently become involved in supporting…”
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14
Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate
Published in Neuron (Cambridge, Mass.) (01-03-1996)“…Three glutamate transporters have been identified in rat, including astroglial transporters GLAST and GLT-1 and a neuronal transporter EAAC1. Here we…”
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15
SYN‐004 (ribaxamase), an oral beta‐lactamase, mitigates antibiotic‐mediated dysbiosis in a porcine gut microbiome model
Published in Journal of applied microbiology (01-07-2017)“…Aim To evaluate an antibiotic inactivation strategy to protect the gut microbiome from antibiotic‐mediated damage. Methods and Results SYN‐004 (ribaxamase) is…”
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16
Aberrant RNA Processing in a Neurodegenerative Disease: the Cause for Absent EAAT2, a Glutamate Transporter, in Amyotrophic Lateral Sclerosis
Published in Neuron (Cambridge, Mass.) (01-03-1998)“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is characterized by selective upper and lower motor neuron degeneration, the…”
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“You Feel Very Isolated”: Effects of COVID-19 Pandemic on Caregiver Social Connections
Published in Gerontology and geriatric medicine (17-12-2021)“…One in five individuals in the United States provides care and support to ill, disabled, and aging family members in the home, leading to feelings of burden,…”
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A Calcium Antagonist vs a Non–Calcium Antagonist Hypertension Treatment Strategy for Patients With Coronary Artery Disease: The International Verapamil-Trandolapril Study (INVEST): A Randomized Controlled Trial
Published in JAMA : the journal of the American Medical Association (03-12-2003)“…CONTEXT Despite evidence of efficacy of antihypertensive agents in treating hypertensive patients, safety and efficacy of antihypertensive agents for coronary…”
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A Limited Opportunity: COVID-19 and Promotion of Advance Care Planning
Published in Palliative medicine reports (01-06-2021)“…Background: Little is known about how COVID-19 has influenced the role of family caregivers in advance care planning (ACP). Objectives: To explore the…”
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20
The Epstein-Barr Virus BZLF1 Protein Inhibits Tumor Necrosis Factor Receptor 1 Expression through Effects on Cellular C/EBP Proteins
Published in Journal of Virology (01-12-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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