Search Results - "Brissette, Janice L"

Phosphoinositide 3-Kinase Signaling to Akt Promotes Keratinocyte Differentiation Versus Death by Calautti, Enzo, Li, Jian, Saoncella, Stefania, Brissette, Janice L., Goetinck, Paul F.

“…Signaling pathways regulating the differentiation program of epidermal cells overlap widely with those activated during apoptosis. How differentiating cells…”
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ABCA12 Maintains the Epidermal Lipid Permeability Barrier by Facilitating Formation of Ceramide Linoleic Esters by Zuo, Ying, Zhuang, Debbie Z., Han, Rong, Isaac, Giorgis, Tobin, Jennifer J., McKee, Mary, Welti, Ruth, Brissette, Janice L., Fitzgerald, Michael L., Freeman, Mason W.

“…Harlequin ichthyosis is a congenital scaling syndrome of the skin in which affected infants have epidermal hyperkeratosis and a defective permeability barrier…”
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Dedicated Epithelial Recipient Cells Determine Pigmentation Patterns by Weiner, Lorin, Han, Rong, Scicchitano, Bianca M., Li, Jian, Hasegawa, Kiyotaka, Grossi, Maddalena, Lee, David, Brissette, Janice L.

“…Mammals generate external coloration via dedicated pigment-producing cells but arrange pigment into patterns through mechanisms largely unknown. Here, using…”
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Finding meaning in chaos: a selection signature for functional interactions and its use in molecular biology by Weiner, Lorin, Brissette, Janice L.

“…A primary goal of biomedical research is to elucidate molecular mechanisms, particularly those responsible for human traits, either normal or pathological. Yet…”
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Bone Morphogenetic Protein Signaling Regulates the Size of Hair Follicles and Modulates the Expression of Cell Cycle-Associated Genes by Sharov, Andrey A., Sharova, Tatyana Y., Mardaryev, Andrei N., di Vignano, Alice Tommasi, Atoyan, Ruzanna, Weiner, Lorin, Yang, Shi, Brissette, Janice L., Dotto, G. Paolo, Botchkarev, Vladimir A.

“…Bone morphogenetic protein (BMP) signaling is involved in the regulation of a large variety of developmental programs, including those controlling organ sizes…”
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An Autoregulatory Loop Directs the Tissue-Specific Expression of p63 through a Long-Range Evolutionarily Conserved Enhancer by Antonini, Dario, Rossi, Barbara, Han, Rong, Minichiello, Annunziata, Di Palma, Tina, Corrado, Marcella, Banfi, Sandro, Zannini, Mariastella, Brissette, Janice L., Missero, Caterina

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A pair of transmembrane receptors essential for the retention and pigmentation of hair by Han, Rong, Beppu, Hideyuki, Lee, Yun-Kyoung, Georgopoulos, Katia, Larue, Lionel, Li, En, Weiner, Lorin, Brissette, Janice L.

“…Hair follicles are simple, accessible models for many developmental processes. Here, using mutant mice, we show that Bmpr2, a known receptor for bone…”
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Bone Morphogenetic Protein (BMP) Signaling Controls Hair Pigmentation by Means of Cross-Talk with the Melanocortin Receptor-1 Pathway by Sharov, Andrey A., Fessing, Michael, Atoyan, Ruzanna, Sharova, Tatyana Y., Haskell-Luevano, Carrie, Weiner, Lorin, Funa, Keiko, Brissette, Janice L., Gilchrest, Barbara A., Botchkarev, Vladimir A., Fuchs, Elaine

“…Hair pigmentation is controlled by tightly coordinated programs of melanin synthesis and involves signaling through the melanocortin type 1 receptor (MC-1R)…”
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The kinase p38α serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression by Park, Jin Mo, Kim, Chun, Sano, Yasuyo, Todorova, Kristina, Carlson, Bradley A, Arpa, Luis, Celada, Antonio, Lawrence, Toby, Otsu, Kinya, Brissette, Janice L, Arthur, J Simon C

“…The function of the kinase p38α in inflammation is unclear. Park and colleagues show that p38α exerts pro- or anti-inflammatory effects depending on the cell…”
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Skin as a living coloring book: how epithelial cells create patterns of pigmentation by Weiner, Lorin, Fu, Wenyu, Chirico, William J., Brissette, Janice L.

“…Summary The pigmentation of mammalian skin and hair develops through the interaction of two basic cell types — pigment donors and recipients. The pigment…”
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A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms by Antonini, Dario, Sirico, Anna, Aberdam, Edith, Ambrosio, Raffaele, Campanile, Carmen, Fagoonee, Sharmila, Altruda, Fiorella, Aberdam, Daniel, Brissette, Janice L, Missero, Caterina

“…p63 is a crucial regulator of epidermal development, but its transcriptional control has remained elusive. Here, we report the identification of a long-range…”
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Modeling by disruption and a selected-for partner for the nude locus by Li, Jian, Lee, Yun-Kyoung, Fu, Wenyu, Whalen, Anne M, Estable, Mario C, Raftery, Laurel A, White, Kristin, Weiner, Lorin, Brissette, Janice L

“…A long-standing problem in biology is how to dissect traits for which no tractable model exists. Here, we screen for genes like the nude locus ( Foxn1 )—genes…”
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Ectopic Expression of the nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia by Prowse, David M, Lee, David, Weiner, Lorin, Jiang, Nanyan, Magro, Cynthia M, Baden, Howard P, Brissette, Janice L

“…Nude mice are characterized by the absence of visible hair, epidermal defects, and the failure to develop a thymus. This phenotype results from…”
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A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans by Mandinova, Anna, Kolev, Vihren, Neel, Victor, Hu, Bing, Stonely, Wesley, Lieb, Jocelyn, Wu, Xunwei, Colli, Claudia, Han, Rong, Pazin, Michael J, Pazin, Mike, Ostano, Paola, Dummer, Reinhard, Brissette, Janice L, Dotto, G Paolo

“…Seborrheic keratoses (SKs) are common, benign epithelial tumors of the skin that do not, or very rarely, progress into malignancy, for reasons that are not…”
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Hair lost in translation by Weiner, Lorin, Brissette, Janice L

“…A new study identifies mutations in the HR gene as the cause of Marie Unna hereditary hypotrichosis (MUHH). The mutations seem to disrupt an unusual leader…”
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Foxn1 promotes keratinocyte differentiation by regulating the activity of protein kinase C by Li, Jian, Baxter, Ruth M., Weiner, Lorin, Goetinck, Paul F., Calautti, Enzo, Brissette, Janice L.

“…The transcription factor Foxn1 (the product of the nude locus) promotes the terminal differentiation of epithelial cells in the epidermis and hair follicles…”
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Exposing the human nude phenotype by Frank, Jorge, Pignata, Claudio, Panteleyev, Andrei A, Prowse, David M, Baden, Howard, Weiner, Lorin, Gaetaniello, Lucia, Ahmad, Wasim, Pozzi, Nicola, Cserhalmi-Friedman, Peter B, Aita, Vincent M, Uyttendaele, Hendrik, Gordon, Derek, Ott, Jurg, Brissette, Janice L, Christiano, Angela M

“…The recent discovery of the human counterpart of the hairless mouse phenotype has helped our understanding of the molecular genetics of hair growth. But there…”
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Role of the Nude Gene in Epithelial Terminal Differentiation by Baxter, Ruth M., Brissette, Janice L.

“…Loss-of-function mutations in Whn (Hfh11, Foxn1), a winged-helix/forkhead transcription factor, cause the nude phenotype, which is characterized by the…”
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Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation by Sharov, Andrei A., Weiner, Lorin, Sharova, Tatyana Y., Siebenhaar, Frank, Atoyan, Ruzanna, Reginato, Anthony M., McNamara, Coleen A., Funa, Keiko, Gilchrest, Barbara A., Brissette, Janice L., Botchkarev, Vladimir A.

“…Contact of developing sensory organs with the external environment is established via the formation of openings in the skin. During eye development, eyelids…”
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Ectodysplasin regulates pattern formation in the mammalian hair coat by Zhang, Min, Brancaccio, Anna, Weiner, Lorin, Missero, Caterina, Brissette, Janice L.

“…In mammalian skin, hair follicles develop at regular intervals and with site‐specific morphologies. This process generates distinct patterns of hair, but the…”
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