Search Results - "Brison, R"

Metabolomics: Current technologies and future trends by Hollywood, Katherine, Brison, Daniel R., Goodacre, Royston

“…The ability to sequence whole genomes has taught us that our knowledge with respect to gene function is rather limited with typically 30–40% of open reading…”
Get full text

Application of extracellular flux analysis for determining mitochondrial function in mammalian oocytes and early embryos by Muller, Bethany, Lewis, Niamh, Adeniyi, Tope, Leese, Henry J., Brison, Daniel R., Sturmey, Roger G.

“…Mitochondria provide the major source of ATP for mammalian oocyte maturation and early embryo development. Oxygen Consumption Rate (OCR) is an established…”
Get full text

The growth of assisted reproductive treatment-conceived children from birth to 5 years: a national cohort study by Hann, Mark, Roberts, Stephen A, D'Souza, Stephen W, Clayton, Peter, Macklon, Nick, Brison, Daniel R

“…Birth weight and early child growth are important predictors of long-term cardiometabolic disease risk, in line with the Developmental Origins of Health and…”
Get full text

Directed differentiation of human embryonic stem cells toward chondrocytes by Baxter, Melissa A, Bates, Nicola, Brison, Daniel R, Oldershaw, Rachel A, Grady, Lisa M, Hardingham, Timothy E, Kimber, Susan J, Soncin, Francesca, Lowe, Emma T

“…Degeneration of articular cartilage in the joints may be amenable to tissue engineering solutions. Oldershaw et al . present an efficient, chemically defined…”
Get full text

A secreted proteomic footprint for stem cell pluripotency by Lewis, Philip A, Silajdžić, Edina, Smith, Helen, Bates, Nicola, Smith, Christopher A, Mancini, Fabrizio E, Knight, David, Denning, Chris, Brison, Daniel R, Kimber, Susan J

“…With a view to developing a much-needed non-invasive method for monitoring the healthy pluripotent state of human stem cells in culture, we undertook proteomic…”
Get full text

Metabolism of the viable mammalian embryo: quietness revisited by Leese, Henry J., Baumann, Christoph G., Brison, Daniel R., McEvoy, Tom G., Sturmey, Roger G.

“…This review examines the ‘Quiet Embryo Hypothesis’ which proposes that viable preimplantation embryos operate at metabolite or nutrient turnover rates…”
Get full text

Human spermbots for patient-representative 3D ovarian cancer cell treatment by Xu, Haifeng, Medina-Sánchez, Mariana, Zhang, Wunan, Seaton, Melanie P H, Brison, Daniel R, Edmondson, Richard J, Taylor, Stephen S, Nelson, Louisa, Zeng, Kang, Bagley, Steven, Ribeiro, Carla, Restrepo, Lina P, Lucena, Elkin, Schmidt, Christine K, Schmidt, Oliver G

“…Cellular micromotors are attractive for locally delivering high concentrations of drug, and targeting hard-to-reach disease sites such as cervical cancer and…”
Get more information

The Quiet Embryo Hypothesis: 20 years on by Leese, Henry J, Brison, Daniel R, Sturmey, Roger G

“…This article revisits the hypothesis, proposed in 2002, that the successful development of oocytes and preimplantation mammalian embryos is associated with a…”
Get full text

How should we assess the safety of IVF technologies? by Brison, Daniel R, Roberts, Stephen A, Kimber, Susan J

“…Abstract Clinical IVF treatment was established over 30 years ago through pioneering work by Edwards and Steptoe and other teams around the world and is now…”
Get full text

Investigating the role of CD44 and hyaluronate in embryo-epithelial interaction using an in vitro model by Berneau, S C, Ruane, P T, Brison, D R, Kimber, S J, Westwood, M, Aplin, J D

“…Implantation failure is an important impediment to increasing success rates in assisted reproductive technologies. Knowledge of the cascade of morphological…”
Get full text

Systems based analysis of human embryos and gene networks involved in cell lineage allocation by Smith, H L, Stevens, A, Minogue, B, Sneddon, S, Shaw, L, Wood, L, Adeniyi, T, Xiao, H, Lio, P, Kimber, S J, Brison, D R

“…Little is understood of the molecular mechanisms involved in the earliest cell fate decision in human development, leading to the establishment of the…”
Get full text

Advanced practice physiotherapy care in emergency departments for patients with musculoskeletal disorders: a pragmatic cluster randomized controlled trial and cost analysis by Matifat, E, Berger Pelletier, E, Brison, R, Hébert, L J, Roy, J-S, Woodhouse, L, Berthelot, S, Daoust, R, Sirois, M-J, Booth, R, Gagnon, R, Miller, J, Tousignant-Laflamme, Y, Emond, M, Perreault, K, Desmeules, F

“…Advanced practice physiotherapy (APP) models of care where physiotherapists are primary contact emergency department (ED) providers are promising models of…”
Get full text

The marker of alkyl DNA base damage, N7-methylguanine, is associated with semen quality in men by Altakroni, B., Nevin, C., Carroll, M., Murgatroyd, C., Horne, G., Brison, D. R., Povey, A. C.

“…Sperm DNA contains a range of DNA base damage that can arise, in part, from exposure to methylating agents. However, the effects are not fully characterized…”
Get full text

Epigenetics and Reproductive Medicine by Huntriss, J, Balen, AH, Sinclair, KD, Brison, DR, Picton, HM

“…In 1942, Conrad H Waddington introduced the term ‘epigenetics’, to describe a biological process that takes place between the genotype and phenotype.1…”
Get full text

The Molecular Karyotype of 25 Clinical-Grade Human Embryonic Stem Cell Lines by Canham, Maurice A., Van Deusen, Amy, Brison, Daniel R., De Sousa, Paul A., Downie, Janet, Devito, Liani, Hewitt, Zoe A., Ilic, Dusko, Kimber, Susan J., Moore, Harry D., Murray, Helen, Kunath, Tilo

“…The application of human embryonic stem cell (hESC) derivatives to regenerative medicine is now becoming a reality. Although the vast majority of hESC lines…”
Get full text

The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development by Morris, I.D., Ilott, S., Dixon, L., Brison, D.R.

“…BACKGROUND: The integrity of sperm DNA is important for the success of natural or assisted fertilization, as well as normal development of the embryo, fetus…”
Get full text

A systematic review of transcriptomic studies of the human endometrium reveals inconsistently reported differentially expressed genes by Walker, Evangeline R, McGrane, Mollie, Aplin, John D, Brison, Daniel R, Ruane, Peter T

“…Genome-wide analysis of gene expression has been widely applied to study the endometrium, although to our knowledge no systematic reviews have been performed…”
Get full text

Global gene expression profiling of individual human oocytes and embryos demonstrates heterogeneity in early development by Shaw, Lisa, Sneddon, Sharon F, Zeef, Leo, Kimber, Susan J, Brison, Daniel R

“…Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to…”
Get full text

Identifying predictors of medically-attended injuries to young children: do child or parent behavioural attributes matter? by Morrongiello, B A, Corbett, M, Brison, R J

“…To investigate whether one can differentiate injured and uninjured young children based on child behavioural attributes or indices of caregiver supervision. A…”
Get more information

Going to extremes: the Goldilocks/Lagom principle and data distribution by Leese, Henry J, Sathyapalan, Thozhukat, Allgar, Victoria, Brison, Daniel R, Sturmey, Roger

“…Numerical data in biology and medicine are commonly presented as mean or median with error or confidence limits, to the exclusion of individual values…”
Get full text