Search Results - "Brisa, S"
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Insulin resistance in depression: A large meta-analysis of metabolic parameters and variation
Published in Neuroscience and biobehavioral reviews (01-08-2022)“…Increased insulin resistance is recognized in psychiatric disorders, such as schizophrenia and bipolar disorder, but its occurrence in depression is less…”
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The new field of 'precision psychiatry'
Published in BMC medicine (13-04-2017)“…Precision medicine is a new and important topic in psychiatry. Psychiatry has not yet benefited from the advanced diagnostic and therapeutic technologies that…”
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Relationship between depression and frailty in older adults: A systematic review and meta-analysis
Published in Ageing research reviews (01-07-2017)“…Highlights • Depression and frailty are two common and pervasive conditions in older age. • We conducted the first meta-analysis exploring the relationship…”
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The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies
Published in Molecular psychiatry (01-08-2021)“…The importance of tryptophan as a precursor for neuroactive compounds has long been acknowledged. The metabolism of tryptophan along the kynurenine pathway and…”
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Depression in cancer: The many biobehavioral pathways driving tumor progression
Published in Cancer treatment reviews (01-01-2017)“…•Depression is highly prevalent among individuals with cancer.•Co-morbid depression may lead to a worse prognosis among cancer patients.•Evidence instantiates…”
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Early Intervention in Bipolar Disorder
Published in The American journal of psychiatry (01-05-2018)“…Bipolar disorder is a recurrent disorder that affects more than 1% of the world population and usually has its onset during youth. Its chronic course is…”
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Statins for the treatment of depression: A meta-analysis of randomized, double-blind, placebo-controlled trials
Published in Journal of affective disorders (01-08-2016)“…Abstract Background In epidemiological studies, statins appear to benefit mood, and there are now some randomized controlled trials examining the efficacy of…”
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Improving drug development in precision psychiatry by ameliorating cognitive biases
Published in European neuropsychopharmacology (01-05-2023)Get full text
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The effect of N-acetylcysteine (NAC) on human cognition – A systematic review
Published in Neuroscience and biobehavioral reviews (01-07-2017)“…•Oxidation and neuroinflammation modulate cognition through a variety of vectors.•NAC mitigates the cognitive effects of neuroinflammation in animals.•Evidence…”
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Charting the proteome landscape in major psychiatric disorders: From biomarkers to biological pathways towards drug discovery
Published in European neuropsychopharmacology (01-08-2022)“…Schizophrenia (SZ), bipolar disorder (BD), and major depressive disorder (MDD) are major mental disorders that affect a significant proportion of the global…”
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Leaky brain in neurological and psychiatric disorders: Drivers and consequences
Published in Australian and New Zealand journal of psychiatry (01-10-2018)“…Background: The blood–brain barrier acts as a highly regulated interface; its dysfunction may exacerbate, and perhaps initiate, neurological and…”
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Innate Immune Cells and C-Reactive Protein in Acute First-Episode Psychosis and Schizophrenia: Relationship to Psychopathology and Treatment
Published in Schizophrenia bulletin (01-03-2020)“…Innate immunity has been linked to initiation of Alzheimer's disease and multiple sclerosis. Moreover, risk of first-episode psychosis (FEP) and schizophrenia…”
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Genetic overlap between Alzheimer’s disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence
Published in Molecular psychiatry (01-08-2024)“…The occurrence of immune disease comorbidities in Alzheimer’s disease (AD) has been observed in both epidemiological and molecular studies, suggesting a…”
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Peripheral Alterations in Cytokine and Chemokine Levels After Antidepressant Drug Treatment for Major Depressive Disorder: Systematic Review and Meta-Analysis
Published in Molecular neurobiology (01-05-2018)“…Mounting evidence suggests that aberrations in immune-inflammatory pathways contribute to the pathophysiology of major depressive disorder (MDD), and…”
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T helper 17 cells may drive neuroprogression in major depressive disorder: Proposal of an integrative model
Published in Neuroscience and biobehavioral reviews (01-05-2016)“…The exact pathophysiology of major depressive disorder (MDD) remains elusive. The monoamine theory, which hypothesizes that MDD emerges as a result of…”
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Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies
Published in Journal of psychiatric research (01-08-2018)“…The development of depression may involve a complex interplay of environmental and genetic risk factors. PubMed and PsycInfo databases were searched from…”
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Dissecting the shared genetic architecture between Alzheimer's disease and frailty: a cross-trait meta-analyses of genome-wide association studies
Published in Frontiers in genetics (2024)“…Frailty is the most common medical condition affecting the aging population, and its prevalence increases in the population aged 65 or more. Frailty is…”
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Use of statins and the risk of dementia and mild cognitive impairment: A systematic review and meta-analysis
Published in Scientific reports (11-04-2018)“…We conducted a systematic review and meta-analysis to investigate whether the use of statins could be associated with the risk of all-caused dementia,…”
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N-Acetylcysteine in depressive symptoms and functionality: a systematic review and meta-analysis
Published in The journal of clinical psychiatry (01-04-2016)“…To assess the utility of N-acetylcysteine administration for depressive symptoms in subjects with psychiatric conditions using a systematic review and…”
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