Search Results - "Brinkmann, U."

Ultrafast anisotropic protein quake propagation after CO photodissociation in myoglobin by Brinkmann, Levin U. L., Hub, Jochen S.

“…“Protein quake” denotes the dissipation of excess energy across a protein, in response to a local perturbation such as the breaking of a chemical bond or the…”
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Molecular-scale characterization of groundwater treatment sludge from around the world: Implications for potential arsenic recovery by Wang, K., Holm, P.E., Trettenes, U. Brinkmann, Bandaru, S.R.S., van Halem, D., van Genuchten, C.M.

“…•As-rich sludge from different groundwater treatment plants was characterized.•As and P content of sludge reached up to 1200 mg/kg and 2 mass%,…”
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Functional Polymorphisms of the Human Multidrug-Resistance Gene: Multiple Sequence Variations and Correlation of One Allele with P-Glycoprotein Expression and Activity in vivo by Hoffmeyer, S., Burk, O., von Richter, O., Arnold, H. P., Brockmoller, J., Johne, A., Cascorbi, I., Gerloff, T., Roots, I., Eichelbaum, M., Brinkmann, U.

“…To evaluate whether alterations in the multidrug-resistance (MDR)-1 gene correlate with intestinal MDR-1 expression and uptake of orally administered…”
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Anisotropic time-resolved solution X-ray scattering patterns from explicit-solvent molecular dynamics by Brinkmann, Levin U L, Hub, Jochen S

“…Time-resolved wide-angle X-ray scattering (TR-WAXS) is an emerging experimental technique used to track chemical reactions and conformational transitions of…”
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Polymorphisms in the ABC drug transporter gene MDR1 by BRINKMANN, U, EICHELBAUM, M

“…In addition to genetically variable metabolic enzymes such as Cyp p450 proteins, blood and tissue levels of many drugs are influenced by controlled transport…”
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CSE1L/CAS: Its role in proliferation and apoptosis by BEHRENS, P, BRINKMANN, U, WELLMANN, A

“…CAS/CSE1L is the human homologue of the yeast gene CSE1. It was first cloned while searching for genes that rendered breast cancer cells resistant towards…”
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ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2 by Kerb, R, Hoffmeyer, S, Brinkmann, U

“…Transport by ATP-dependent efflux pumps, such as P-glycoprotein (PGP) and multi-drug resistance related proteins (MRPs), influences bioavailability and…”
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Quantification of cell surface proteins with bispecific antibodies by Panke, C., Weininger, D., Haas, A., Schelter, F., Schlothauer, T., Bader, S., Sircar, R., Josel, H.P., Baer, U., Burtscher, H., Mundigl, O., Grote, M., Brinkmann, U., Sustmann, C.

“…Flow cytometry is an established method for fast and accurate quantitation of cellular protein levels and requires fluorescently labeled antibodies as well as…”
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LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism by Tiller, G, Laumen, H, Fischer-Posovszky, P, Finck, A, Skurk, T, Keuper, M, Brinkmann, U, Wabitsch, M, Link, D, Hauner, H

“…Objective: The member of the tumor necrosis factor family LIGHT (lymphotoxin-like inducible protein that competes with glycoprotein D for herpesvirus entry on…”
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Hydrodynamic analogy approach for modelling of reactive stripping with structured catalyst supports by Brinkmann, U., Schildhauer, T.J., Kenig, E.Y.

“…Modelling of gas/vapour–liquid separation processes usually requires experimentally determined parameters, e.g., mass transfer coefficients. This results in…”
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The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels by KERB, R, AYNACIOGLU, A. S, GÜZELBEY, P, ROOTS, I, BRINKMANN, U, BROCKMÖLLER, J, SCHLAGENHAUFER, R, BAUER, S, SZEKERES, T, HAMWI, A, FRITZER-SZEKERES, M, BAUMGARTNER, C, ÖNGEN, H. Z

“…Phenytoin, an anticonvulsant, exhibits nonlinear pharmacokinetics with large interindividual differences. Because of its small therapeutic range with the risk…”
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MODELING OF TRANSPORT PHENOMENA IN TWO-PHASE FILM-FLOW SYSTEMS: APPLICATION TO MONOLITH REACTORS by Mueller, I., Brinkmann, U., Kenig, E. Y.

“…Transport phenomena in two-phase systems represent the basis of many industrial processes. The hydrodynamic behavior and process kinetics are crucial,…”
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Cloning and Characterization of a Cellular Apoptosis Susceptibility Gene, the Human Homologue to the Yeast Chromosome Segregation Gene CSE1 by Brinkmann, Ulrich, Brinkmann, Elisabeth, Gallo, Maria, Pastan, Ira

“…We recently isolated human cDNA fragments that render MCF-7 breast cancer cells resistant to cell death caused by Pseudomonas exotoxin, Pseudomonas…”
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MODELLING AND SIMULATION OF A PACKED SULPHUR DIOXIDE ABSORPTION UNIT USING THE HYDRODYNAMIC ANALOGY APPROACH by U. Brinkmann, E. Kenig, R. Thiele, M. Haas

“…Abstract preview not available - see full-text PDF article…”
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Implication of the proliferation and apoptosis associated CSE1L/CAS gene for breast cancer development by Behrens, P, Brinkmann, U, Fogt, F, Wernert, N, Wellmann, A

“…The CSEIL/CAS protein (CAS) is a Ran-binding protein with a function as a nuclear transport (export) factor. CSEIL/CAS, similar to Ran and other ran-binding…”
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B3(Fv)-PE38KDEL, A Single-Chain Immunotoxin that Causes Complete Regression of a Human Carcinoma in Mice by Brinkmann, Ulrich, Pai, Lee H., FitzGerald, David J., Willingham, Mark, Pastan, Ira

“…The genes encoding the heavy- and light-chain Fv regions of the monoclonal murine antibody B3, which recognizes a carbohydrate antigen on the surface of many…”
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The human CAS (cellular apoptosis susceptibility) gene mapping on chromosome 20q13 is amplified in BT474 breast cancer cells and part of aberrant chromosomes in breast and colon cancer cell lines by Brinkmann, U, Gallo, M, Polymeropoulos, M H, Pastan, I

“…The CAS (cellular apoptosis susceptibility) gene is the human homolog of the yeast chromosome segregation gene CSE1. CAS may have a dual function in mammalian…”
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Conjugation of an antibody Fv fragment to a virus coat protein: cell-specific targeting of recombinant polyoma-virus-like particles by Stubenrauch, K, Gleiter, S, Brinkmann, U, Rudolph, R, Lilie, H

“…The development of cell-type-specific delivery systems is highly desirable for gene-therapeutic applications. Current virus-based vector systems show broad…”
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A Recombinant Immunotoxin Containing a Disulfide-Stabilized Fv Fragment by Brinkmann, Ulrich, Reiter, Yoram, Jung, Sun-Hee, Lee, Byungkook, Pastan, Ira

“…B3(dsFv)-PE38KDEL is a recombinant immunotoxin composed of the Fv region of monoclonal antibody B3 connected to a truncated form of Pseudomonas exotoxin…”
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Common denominator procedure: a novel approach to gene-expression data mining for identification of phenotype-specific genes by Korn, René, Röhrig, Sascha, Schulze-Kremer, Steffen, Brinkmann, Ulrich

“…Motivation: We have established a novel data mining procedure for the identification of genes associated with pre-defined phenotypes and/or molecular pathways…”
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