Search Results - "Brinkmann, Joscha"
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In-Silico Screening of Lipid-Based Drug Delivery Systems
Published in Pharmaceutical research (01-12-2020)“…Purpose This work proposes an in-silico screening method for identifying promising formulation candidates in complex lipid-based drug delivery systems (LBDDS)…”
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Solubility of Pharmaceutical Ingredients in Natural Edible Oils
Published in Molecular pharmaceutics (06-07-2020)“…Natural edible oils (NEOs) are common excipients for lipid-based formulations. Many of them are complex mixtures comprising hundreds of different triglycerides…”
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Solubility of pharmaceutical ingredients in triglycerides
Published in European journal of pharmaceutics and biopharmaceutics (01-12-2019)“…[Display omitted] Lipid-based drug delivery systems (LBDDS) are highly relevant as pharmaceutical formulations significantly enhancing the bioavailability of…”
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Predicting the API partitioning between lipid-based drug delivery systems and water
Published in International journal of pharmaceutics (15-02-2021)“…[Display omitted] Partitioning tests in water are early-stage standard experiments during the development of pharmaceutical formulations, e.g. of lipid-based…”
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PC-SAFT Modeling of Phase Equilibria Relevant for Lipid-Based Drug Delivery Systems
Published in Journal of chemical and engineering data (11-03-2021)“…In this work we investigated the solubilities of 10 active pharmaceutical ingredients (APIs), namely, fenofibrate, ibuprofen, cinnarizine, carbamazepine,…”
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Thermodynamic Modeling of Triglycerides using PC-SAFT
Published in Journal of chemical and engineering data (11-04-2019)“…Vapor pressures for the saturated triglycerides (TGs) tricaprylin, tricaprin, and liquid densities of tricaprylin were experimentally determined. TG…”
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Phase Behavior of Binary Mixtures Containing Succinic Acid or Its Esters
Published in Journal of chemical and engineering data (13-07-2017)“…This work provides experimental data and thermodynamic modeling on phase equilibria of binary mixtures that are relevant for esterification reactions. The…”
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Solubility predictions of acetanilide derivatives in water: Combining thermochemistry and thermodynamic modeling
Published in Fluid phase equilibria (15-01-2018)“…Knowledge about solubility in water is required for crystallization processes, for the development of structure-property relationships, for the establishment…”
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