Search Results - "Brinkmann, Berit J."
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Processing human lymph node samples for single-cell assays
Published in STAR protocols (17-12-2021)“…Most non-Hodgkin's lymphomas grow exclusively in the lymph node compartment protected by the tumor microenvironment. To better understand the cellular…”
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CD20-bispecific antibodies improve response to CD19-CAR T cells in lymphoma in vitro and CLL in vivo models
Published in Blood (15-08-2024)“…•CD20/CD3 bispecific antibody enhances the efficacy of CD19–directed CAR T cells.•Combination treatment improved survival in the Eμ-TCL-1 mouse model. [Display…”
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Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities
Published in Nature cell biology (01-03-2024)“…The redirection of T cells has emerged as an attractive therapeutic principle in B cell non-Hodgkin lymphoma (B-NHL). However, a detailed characterization of…”
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An autologous culture model of nodal B-cell lymphoma identifies ex vivo determinants of response to bispecific antibodies
Published in Blood advances (14-12-2021)“…Bispecific antibodies (BsAbs) can induce long-term responses in patients with refractory and relapsed B-cell lymphoma. Nevertheless, response rates across…”
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Proteogenomics refines the molecular classification of chronic lymphocytic leukemia
Published in Nature communications (20-10-2022)“…Cancer heterogeneity at the proteome level may explain differences in therapy response and prognosis beyond the currently established genomic and…”
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