Search Results - "Brinkmann, Antje"

Expression of viral CD45 ligand E3/49K on porcine cells reduces human anti-pig immune responses by Pokoyski, Claudia, Baars, Wiebke, Windheim, Mark, Reubold, Thomas F., Zischke, Jasmin, Brinkmann, Antje, Kay-Fedorov, Penelope C., Schwinzer, Reinhard

“…Transgenic expression of protective molecules in porcine cells and tissues is a promising approach to prevent xenograft rejection. Viruses have developed…”
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Triple (GGTA1, CMAH, B2M) modified pigs expressing an SLA class I low phenotype-Effects on immune status and susceptibility to human immune responses by Hein, Rabea, Sake, Hendrik J, Pokoyski, Claudia, Hundrieser, Joachim, Brinkmann, Antje, Baars, Wiebke, Nowak-Imialek, Monika, Lucas-Hahn, Andrea, Figueiredo, Constanca, Schuberth, Hans-Joachim, Niemann, Heiner, Petersen, Björn, Schwinzer, Reinhard

“…Porcine xenografts lacking swine leukocyte antigen (SLA) class I are thought to be protected from human T cell responses. We have previously shown that SLA…”
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Pigs expressing the human inhibitory ligand PD‐L1 (CD 274) provide a new source of xenogeneic cells and tissues with low immunogenic properties by Buermann, Anna, Petkov, Stoyan, Petersen, Björn, Hein, Rabea, Lucas‐Hahn, Andrea, Baars, Wiebke, Brinkmann, Antje, Niemann, Heiner, Schwinzer, Reinhard

“…Background The programmed cell death‐1 (PD‐1, CD279)/PD‐Ligand1 (PD‐L1, CD274) receptor system is crucial for controlling the balance between immune activation…”
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Possible detrimental effects of beta‐2‐microglobulin knockout in pigs by Sake, Hendrik Johannes, Frenzel, Antje, Lucas‐Hahn, Andrea, Nowak‐Imialek, Monika, Hassel, Petra, Hadeler, Klaus‐Gerd, Hermann, Doris, Becker, Roswitha, Eylers, Heinke, Hein, Rabea, Baars, Wiebke, Brinkmann, Antje, Schwinzer, Reinhard, Niemann, Heiner, Petersen, Björn

“…Background Despite major improvements in pig‐to‐primate xenotransplantation, long‐term survival of xenografts is still challenging. The major…”
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Role of human and porcine MHC DRB1 alleles in determining the intensity of individual human anti‐pig T‐cell responses by Hundrieser, Joachim, Hein, Rabea, Pokoyski, Claudia, Brinkmann, Antje, Düvel, Heike, Dinkel, Astrid, Trautewig, Britta, Siegert, Janina‐Franziska, Römermann, Dorothee, Petersen, Björn, Schwinzer, Reinhard

“…Background Differences in quality and strength of immune responses between individuals are mainly due to polymorphisms in major histocompatibility complex…”
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Triple (GGTA1, CMAH, B2M) modified pigs expressing an SLA class Ilow phenotype—Effects on immune status and susceptibility to human immune responses by Hein, Rabea, Sake, Hendrik J., Pokoyski, Claudia, Hundrieser, Joachim, Brinkmann, Antje, Baars, Wiebke, Nowak‐Imialek, Monika, Lucas‐Hahn, Andrea, Figueiredo, Constanca, Schuberth, Hans‐Joachim, Niemann, Heiner, Petersen, Björn, Schwinzer, Reinhard

“…Porcine xenografts lacking swine leukocyte antigen (SLA) class I are thought to be protected from human T cell responses. We have previously shown that SLA…”
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