Search Results - "Brinkley, Tina E."

Effect of exercise training on chronic inflammation by Beavers, Kristen M., Brinkley, Tina E., Nicklas, Barbara J.

“…Persistent, sub-clinical inflammation, as indicated by higher circulating levels of inflammatory mediators, is a prominent risk factor for several chronic…”
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Soluble receptor for advanced glycation end products and the risk for incident heart failure: The Atherosclerosis Risk in Communities Study by Lazo, Mariana, MD, PhD, ScM, Halushka, Marc K., MD, PhD, Shen, Lu, ScM, Maruthur, Nisa, MD, MHS, Rebholz, Casey M., PhD, Rawlings, Andreea M., MS, Hoogeveen, Ron C., PhD, Brinkley, Tina E., PhD, Ballantyne, Christie M., MD, Astor, Brad C., PhD, MPH, Selvin, Elizabeth, PhD, MPH

“…Abstract Background Experimental studies in animals suggest that circulating soluble receptor for advanced glycation end products (sRAGE) decrease oxidative…”
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Changes in Adiposity and Cerebrospinal Fluid Biomarkers Following a Modified Mediterranean Ketogenic Diet in Older Adults at Risk for Alzheimer's Disease by Brinkley, Tina E, Leng, Iris, Register, Thomas C, Neth, Bryan J, Zetterberg, Henrik, Blennow, Kaj, Craft, Suzanne

“…Ketogenic diets have been used to treat both obesity and neurological disorders, including epilepsy and more recently Alzheimer's disease (AD), likely due to…”
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Renal Sinus Fat and Poor Blood Pressure Control in Middle-Aged and Elderly Individuals at Risk for Cardiovascular Events by Chughtai, Haroon L, Morgan, Timothy M, Rocco, Michael, Stacey, Brandon, Brinkley, Tina E, Ding, Jingzhong, Nicklas, Barbara, Hamilton, Craig, Hundley, W. Gregory

“…Fat in the renal sinus (RS), a region of the kidney in which low pressure venous and lymphatic vessels are present, may indirectly influence blood pressure…”
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Exercise training as a treatment for chronic inflammation in the elderly by Nicklas, Barbara J, Brinkley, Tina E

“…Persistent subclinical inflammation predisposes to chronic disease, as well as the development of sarcopenia and disability, in frail elderly. Thus, the…”
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Circulating MiRNAs as biomarkers of gait speed responses to aerobic exercise training in obese older adults by Zhang, Tan, Brinkley, Tina E, Liu, Keqin, Feng, Xin, Marsh, Anthony P, Kritchevsky, Stephen, Zhou, Xiaobo, Nicklas, Barbara J

“…Gait speed is a useful predictor of adverse outcomes, including incident mobility disability and mortality in older adults. While aerobic exercise training…”
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Long-Term Effects of an Intensive Lifestyle Intervention on Electrocardiographic Criteria for Left Ventricular Hypertrophy: The Look AHEAD Trial by Brinkley, Tina E, Anderson, Andrea, Soliman, Elsayed Z, Bertoni, Alain G, Greenway, Frank, Knowler, William C, Glasser, Stephen P, Horton, Edward S, Espeland, Mark A

“…Abstract BACKGROUND Left ventricular hypertrophy assessed by electrocardiography (ECG-LVH) is a marker of subclinical cardiac damage and a strong predictor of…”
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Adiposity Is Associated with Gender-Specific Reductions in Left Ventricular Myocardial Perfusion during Dobutamine Stress by Hall, Michael E, Brinkley, Tina E, Chughtai, Haroon, Morgan, Timothy M, Hamilton, Craig A, Jordan, Jennifer H, Stacey, R Brandon, Soots, Sandra, Hundley, W Gregory

“…Obesity and visceral adiposity are increasingly recognized risk factors for cardiovascular disease. Visceral fat may reduce myocardial perfusion by impairing…”
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Elevated Soluble Lectin-like Oxidized LDL Receptor-1 (sLOX-1) Levels in Obese Postmenopausal Women by Brinkley, Tina E., Kume, Noriaki, Mitsuoka, Hirokazu, Phares, Dana A., Hagberg, James M.

“…We investigated the association between soluble lectin‐like oxidized low‐density lipoprotein receptor‐1 (sLOX‐1) levels and obesity in older women. Fifty‐one…”
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Detection of the receptor for advanced glycation endproducts in neuronally-derived exosomes in plasma by Patterson, Sierra A., Deep, Gagan, Brinkley, Tina E.

“…Exosomes are nanovesicles that participate in cell-to-cell communication and are secreted by a variety of cells including neurons. Recent studies suggest that…”
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Pericardial fat and myocardial perfusion in asymptomatic adults from the Multi-Ethnic Study of Atherosclerosis by Brinkley, Tina E, Jerosch-Herold, Michael, Folsom, Aaron R, Carr, J Jeffrey, Hundley, W Gregory, Allison, Matthew A, Bluemke, David A, Burke, Gregory L, Szklo, Moyses, Ding, Jingzhong

“…Pericardial fat has adverse effects on the surrounding vasculature. Previous studies suggest that pericardial fat may contribute to myocardial ischemia in…”
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Dietary protein intake and circulating advanced glycation end product/receptor for advanced glycation end product concentrations in the Health, Aging, and Body Composition Study by Brinkley, Tina E, Semba, Richard D, Kritchevsky, Stephen B, Houston, Denise K

“…Advanced glycation end products (AGEs) promote adverse health effects and may contribute to the multi-system functional decline observed in aging. Diet is a…”
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Effects of Exercise and Weight Loss on Proximal Aortic Stiffness in Older Adults With Obesity by Brinkley, Tina E., Leng, Iris, Bailey, Margie J., Houston, Denise K., Hugenschmidt, Christina E., Nicklas, Barbara J., Hundley, W. Gregory

“…Obesity may accelerate age-related increases in aortic stiffness. Although aerobic exercise training generally has favorable effects on aortic structure and…”
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Variation in the human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gene is associated with plasma soluble LOX-1 levels by Brinkley, Tina E., Kume, Noriaki, Mitsuoka, Hirokazu, Brown, Michael D., Phares, Dana A., Ferrell, Robert E., Kita, Toru, Hagberg, James M.

“…The lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) expressed on vascular cells plays a major role in atherogenesis by internalizing and…”
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Effects of Caloric Restriction on Cardiorespiratory Fitness, Fatigue, and Disability Responses to Aerobic Exercise in Older Adults With Obesity: A Randomized Controlled Trial by Nicklas, Barbara J, Brinkley, Tina E, Houston, Denise K, Lyles, Mary F, Hugenschmidt, Christina E, Beavers, Kristen M, Leng, Xiaoyan

“…Obesity compounds aging-related declines in cardiorespiratory fitness, with accompanying fatigue and disability. This study determined the effects of two…”
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Regional Adipose Distribution and its Relationship to Exercise Intolerance in Older Obese Patients Who Have Heart Failure With Preserved Ejection Fraction by Haykowsky, Mark J., Nicklas, Barbara J., Brubaker, Peter H., Hundley, W. Gregory, Brinkley, Tina E., Upadhya, Bharathi, Becton, J. Thomas, Nelson, Michael D., Chen, Haiying, Kitzman, Dalane W.

“…This study sought to test the hypothesis that older obese patients with heart failure with preserved ejection fraction (HFpEF) have significantly greater…”
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Adiposity, immunity, and inflammation: interrelationships in health and disease: a report from 24th Annual Harvard Nutrition Obesity Symposium, June 2023 by Burak, Mehmet Furkan, Stanley, Takara L, Lawson, Elizabeth A, Campbell, Sophia L, Lynch, Lydia, Hasty, Alyssa H, Domingos, Ana I, Dixit, Vishwa D, Hotamışlıgil, Gökhan S, Sheedy, Frederick J, Dixon, Anne E, Brinkley, Tina E, Hill, Joseph A, Donath, Marc Y, Grinspoon, Steven K

“…The rapidly evolving field of immunometabolism explores how changes in local immune environments may affect key metabolic and cellular processes, including…”
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Heterogeneity of Physical Function Responses to Exercise Training in Older Adults by Chmelo, Elizabeth A., Crotts, Charlotte I., Newman, Jill C., Brinkley, Tina E., Lyles, Mary F., Leng, Xiaoyan, Marsh, Anthony P., Nicklas, Barbara J.

“…Objectives To describe the interindividual variability in physical function responses to supervised resistance and aerobic exercise training interventions in…”
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Aging, Race, and Health Disparities: Recommendations From the Research Centers Collaborative Network by Jain, Snigdha, Bey, Ganga S, Forrester, Sarah N, Rahman-Filipiak, Annalise, Thompson Gonzalez, Nicole, Petrovsky, Darina V, Kritchevsky, Stephen B, Brinkley, Tina E

“…Racial disparities in adverse health outcomes with aging have been well described. Yet, much of the research focuses on racial comparisons, with relatively…”
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Association of Breathing Reserve at Peak Exercise With Body Composition and Physical Function in Older Adults With Obesity by Opina, Maria Theresa D, Brinkley, Tina E, Gordon, Michelle, Lyles, Mary F, Nicklas, Barbara J

“…Abstract Background Adiposity-related ventilatory constraints in older adults can potentially contribute to greater risk of exercise intolerance and mobility…”
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