Search Results - "Brinkhuis, Remco F."

The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by VAN HERWAARDEN, Antonius E, JONKER, Johan W, WAGENAAR, Els, BRINKHUIS, Remco F, SCHELLENS, Jan H. M, BEIJNEN, Jos H, SCHINKEL, Alfred H

“…The food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is the most abundant heterocyclic amine found in various protein containing foods…”
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Role of Breast Cancer Resistance Protein in the Bioavailability and Fetal Penetration of Topotecan by Jonker, Johan W., Smit, Johan W., Brinkhuis, Remco F., Maliepaard, Marc, Beijnen, Jos H., Schellens, Jan H. M., Schinkel, Alfred H.

“…Background and Methods: Breast cancer resistance protein (BCRP/MXR/ABCP) is a multidrug-resistance protein that is a member of the adenosine…”
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The mouse Bcrp1/Mxr/Abcp gene : Amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin by ALLEN, J. D, BRINKHUIS, R. F, WIJNHOLDS, J, SCHINKEL, A. H

“…Mouse fibroblast cell lines lacking functional Mdr1a, Mdr1b, and Mrp1 genes were selected for resistance to topotecan, mitoxantrone, or doxorubicin. Each of…”
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Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance by ALLEN, John D, BRINKHUIS, Remco F, VAN DEEMTER, Liesbeth, WIJNHOLDS, Jan, SCHINKEL, Alfred H

“…Despite accumulating evidence that multidrug resistance transporter proteins play a part in drug resistance in some clinical cancers, it remains unclear…”
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