Search Results - "Brinke, A"

Three phenotypes of adult‐onset asthma by Amelink, M., Nijs, S. B., Groot, J. C., Tilburg, P. M. B., Spiegel, P. I., Krouwels, F. H., Lutter, R., Zwinderman, A. H., Weersink, E. J. M., Brinke, A., Sterk, P. J., Bel, E. H.

“…Rationale Adult‐onset asthma differs from childhood‐onset asthma in many respects. It is more heterogeneous, often severe and frequently associated with loss…”
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Prediction of response to biological treatment with monoclonal antibodies in severe asthma by Kroes, J.A., Zielhuis, S.W., van Roon, E.N., ten Brinke, A.

“…[Display omitted] In recent years, major developments have occurred in severe asthma management. Different asthma phenotypes and subgroups have been identified…”
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Frequent exacerbators - a distinct phenotype of severe asthma by Kupczyk, M., ten Brinke, A., Sterk, P. J., Bel, E. H., Papi, A., Chanez, P., Nizankowska-Mogilnicka, E., Gjomarkaj, M., Gaga, M., Brusselle, G., Dahlén, B., Dahlén, S.-E.

“…Summary Background Exacerbations represent a major source of morbidity and mortality in asthma and are a prominent feature of poorly controlled,…”
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Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years by Klarenbeek, P L, Remmerswaal, E B M, ten Berge, I J M, Doorenspleet, M E, van Schaik, B D C, Esveldt, R E E, Koch, S D, ten Brinke, A, van Kampen, A H C, Bemelman, F J, Tak, P P, Baas, F, de Vries, N, van Lier, R A W

“…CD8(+) T-cell responses against latent viruses can cover considerable portions of the CD8(+) T-cell compartment for many decades, yet their initiation and…”
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Repeated vaccination with tetanus toxoid of plasma donors with pre‐existing specific IgE transiently elevates tetanus‐specific IgE but does not induce allergic symptoms by Unger, P. P., Makuch, M., Aalbers, M., Derksen, N. I. L., Brinke, A., Aalberse, R. C., Rispens, T., Ham, S. M.

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Risk factors of frequent exacerbations in difficult-to-treat asthma by ten Brinke, A, Sterk, P. J, Masclee, A. A. M, Spinhoven, P, Schmidt, J. T, Zwinderman, A. H, Rabe, K. F, Bel, E. H

“…Recurrent exacerbations are a major cause of morbidity and medical expenditure in patients with asthma. Various exogenous and endogenous factors are thought to…”
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Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity by Kavazović, Inga, Han, Hongya, Balzaretti, Giulia, Slinger, Erik, Lemmermann, Niels A W, Ten Brinke, Anja, Merkler, Doron, Koster, Jan, Bryceson, Yenan T, de Vries, Niek, Jonjić, Stipan, Klarenbeek, Paul L, Polić, Bojan, Eldering, Eric, Wensveen, Felix M

“…The memory CD8 T-cell pool must select for clones that bind immunodominant epitopes with high affinity to efficiently counter reinfection. At the same time, it…”
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The perceived waning of biologics in severe asthma by Kroes, J.A., Van Hal, L.H.G., Van Dijk, L., Zielhuis, S.W., Van Der Meer, A.N., Van Roon, E.N., Ten Brinke, A.

“…Biologics are highly effective in severe asthma and used at fixed dosing intervals. However, in clinical practice, dosing intervals are sometimes shortened if…”
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Home-based intravenous treatment with reslizumab for severe asthma in the Netherlands – An evaluation by Bendien, S.A., van Leeuwen, M.M., Lau, H.S., Ten Brinke, A., Visser, L.E., de Koning, E.M., Braunstahl, G.J.

“…The anti-IL-5 biologic reslizumab for the treatment of severe eosinophilic asthma is administered intravenously. In the current study home administration of…”
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Enhanced uptake of blood coagulation factor VIII containing immune complexes by antigen presenting cells by Hartholt, R. B., Wroblewska, A., Herczenik, E., Peyron, I., ten Brinke, A., Rispens, T., Nolte, M. A., Slot, E., Claassens, J. W., Nimmerjahn, F., Verbeek, J. S., Voorberg, J.

“…Essentials Anti‐factor (F) VIII antibody formation is a major complication in the treatment of hemophilia A. We investigated uptake of FVIII and FVIII immune…”
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Left atrial strain is related to adverse events in patients after acute myocardial infarction treated with primary percutaneous coronary intervention by Antoni, M Louisa, ten Brinke, Ellen A, Atary, Jael Z, Marsan, Nina Ajmone, Holman, Eduard R, Schalij, Martin J, Bax, Jeroen J, Delgado, Victoria

“…Left atrial (LA) maximal volume is of prognostic value in patients after acute myocardial infarction (AMI). Recently, LA mechanical function and LA strain have…”
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Airway inflammation in obese and nonobese patients with difficult-to-treat asthma by van Veen, I.H, ten Brinke, A, Sterk, P.J, Rabe, K.F, Bel, E.H

“…Asthma and obesity are associated disorders, but the contribution of obesity to difficult-to-treat asthma as well as the mechanisms responsible for this…”
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Exhaled nitric oxide predicts lung function decline in difficult-to-treat asthma by van Veen, I. H, ten Brinke, A, Sterk, P. J, Sont, J. K, Gauw, S. A, Rabe, K. F, Bel, E. H

“…A subset of patients with asthma is known to have progressive loss of lung function despite treatment with corticosteroids. The aim of the present study was to…”
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Anti-IL-5/5Ra biologics improve work productivity and activity in severe asthma: a RAPSODI registry-based cohort study by van der Valk, J. P. M., Hekking, P. P., Rauh, S. P., Patberg, K. W., van Veen, I. A., Van Huisstede, A., Smeenk, F. W. J. M., van de Ven, M. J. T., Broeders, M. E. A. C., Hilvering, B., van Exsel, J., Oud, K. T. M., Langeveld, B., Fieten, K. B., van Veen, A., Hashimoto, S., Sont, J. K., ten Brinke, A., Braunstahl, G. J.

“…Severe asthma is associated with a serious disease burden, partially caused by limitations in activity and work impairment. This study aims to relate treatment…”
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Longitudinal humoral response after SARS-CoV-2 vaccination in ocrelizumab treated MS patients: To wait and repopulate? by van Kempen, Z.L.E., Wieske, L., Stalman, E.W., Kummer, L. Y. L, van Dam, P.J., Volkers, A.G., Boekel, L., Toorop, A.A., Strijbis, E.M.M., Tas, S.W., Wolbink, G.J., Löwenberg, M., van Sandt, C., ten Brinke, A., Verstegen, N.J.M., Steenhuis, M., Kuijpers, T.W., van Ham, S.M., Rispens, T., Eftimov, F., Killestein, J.

“…The objective of this study was to measure humoral responses after SARS-CoV-2 vaccination in MS patients treated with ocrelizumab (OCR) compared to MS patients…”
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Non-atopic males with adult onset asthma are at risk of persistent airflow limitation by Amelink, M., de Nijs, S. B., Berger, M., Weersink, E. J., ten Brinke, A., Sterk, P. J., Bel, E. H.

“…Summary Background Patients with asthma have on average a more rapid decline in FEV 1 as compared with the general population. Recent cluster analysis has…”
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Comprehensive Assessment of Changes in Left Atrial Volumes and Function after ST-Segment Elevation Acute Myocardial Infarction: Role of Two-Dimensional Speckle-Tracking Strain Imaging by Antoni, M. Louisa, MD, ten Brinke, Ellen A., MD, Marsan, Nina Ajmone, MD, Atary, Jael Z., MD, Holman, Eduard R., MD, PhD, van der Wall, Ernst E., MD, PhD, Schalij, Martin J., MD, PhD, Bax, Jeroen J., MD, PhD, Delgado, Victoria, MD, PhD

“…Background Left atrial (LA) size has been associated with adverse outcome in patients after acute myocardial infarction. However, data about the occurrence of…”
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Predictive Value of Total Atrial Conduction Time Estimated With Tissue Doppler Imaging for the Development of New-Onset Atrial Fibrillation After Acute Myocardial Infarction by Antoni, M. Louisa, MD, Bertini, Matteo, MD, Atary, Jael Z., MD, Delgado, V., MD, ten Brinke, Ellen A., MD, Boersma, Eric, PhD, Holman, Eduard R., MD, PhD, van der Wall, Ernst E., MD, PhD, Schalij, Martin J., MD, PhD, Bax, Jeroen J., MD, PhD, van de Veire, Nico R.L., MD, PhD

“…Patients who develop new-onset atrial fibrillation (AF) after acute myocardial infarction (AMI) show an increased risk for adverse events and mortality during…”
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Single-beat estimation of the left ventricular end-systolic pressure-volume relationship in patients with heart failure by Ten Brinke, E. A., Klautz, R. J., Verwey, H. F., Van Der Wall, E. E., Dion, R. A., Steendijk, P.

“…Aim:  The end‐systolic pressure–volume relationship (ESPVR) constructed from multiple pressure–volume (PV) loops acquired during load intervention is an…”
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Single-beat estimation of the left ventricular end-diastolic pressure-volume relationship in patients with heart failure by Ten Brinke, Ellen A, Burkhoff, Daniel, Klautz, Robert J, Tschöpe, Carsten, Schalij, Martin J, Bax, Jeroen J, van der Wall, Ernst E, Dion, Robert A, Steendijk, Paul

“…To test a method to predict the end-diastolic pressure-volume relationship (EDPVR) from a single beat in patients with heart failure. Patients (New York Heart…”
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