Search Results - "Brini, M."

The plasma membrane Ca²+ ATPase and the plasma membrane sodium calcium exchanger cooperate in the regulation of cell calcium by Brini, Marisa, Carafoli, Ernesto

“…Calcium is an ambivalent signal: it is essential for the correct functioning of cell life, but may also become dangerous to it. The plasma membrane Ca(2+)…”
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Regulation of Cell Calcium and Role of Plasma Membrane Calcium ATPases by Calì, T, Brini, M, Carafoli, E

“…The plasma membrane Ca ATPase (PMCA pump) is a member of the superfamily of P-type pumps. It has 10 transmembrane helices and 2 cytosolic loops, one of which…”
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Reduced mitochondrial Ca2+ transients stimulate autophagy in human fibroblasts carrying the 13514A>G mutation of the ND5 subunit of NADH dehydrogenase by Granatiero, V, Giorgio, V, Calì, T, Patron, M, Brini, M, Bernardi, P, Tiranti, V, Zeviani, M, Pallafacchina, G, De Stefani, D, Rizzuto, R

“…Mitochondrial disorders are a group of pathologies characterized by impairment of mitochondrial function mainly due to defects of the respiratory chain and…”
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ADVANCEDMONITORING SYSTEMS FOR LANDSLIDE RISK REDUCTION IN THE'SIQ' OF PETRA (JORDAN) by Delmonaco, G., Brini, M., Cesaro, G.

“…The UNESCO World Heritage Site of Petra is characterized by a spectacular geo-archaeological landscape that lead to its inscription as World Heritage Site in…”
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functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness by Ficarella, R, Di Leva, F, Bortolozzi, M, Ortolano, S, Donaudy, F, Petrillo, M, Melchionda, S, Lelli, A, Domi, T, Fedrizzi, L, Lim, D, Shull, G.E, Gasparini, P, Brini, M, Mammano, F, Carafoli, E

“…Ca²⁺ enters the stereocilia of hair cells through mechanoelectrical transduction channels opened by the deflection of the hair bundle and is exported back to…”
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Calcium signalling: a historical account, recent developments and future perspectives by Brini, M, Carafoli, E

“…Ca2+ is a uniquely important messenger that penetrates into cells through gated channels to transmit signals to a large number of enzymes. The evolutionary…”
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Calcium signaling and disease: Preface by Brini, M., Carafoli, E.

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Erythrocyte and reticulocyte indices in iron deficiency in chronic kidney disease: comparison of two methods by Maconi, M., Cavalca, L., Danise, P., Cardarelli, F., Brini, M.

“…Objective. Anaemia is a common complication of chronic kidney disease (CKD), particularly in dialysis patients. The recent European guidelines for anaemia…”
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Effects of PMCA and SERCA pump overexpression on the kinetics of cell Ca2+ signalling by Brini, Marisa, Bano, Daniele, Manni, Sabrina, Rizzuto, Rosario, Carafoli, Ernesto

“…The dynamic interactions of the main pathways for active Ca2+ transport have been analysed in living cells by altering the expression of their components. The…”
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Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells by Montero, M., Brini, M., Marsault, R., Alvarez, J., Sitia, R., Pozzan, T., Rizzuto, R.

“…Direct monitoring of the free Ca2+ concentration in the lumen of the endoplasmic reticulum (ER) is an important but still unsolved experimental problem. We…”
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Mitochondria as biosensors of calcium microdomains by Rizzuto, R., Pinton, P., Brini, M., Chiesa, A., Filippin, L., Pozzan, T.

“…The notion that the agonist-dependent increases in intracellular Ca2+concentration, on ubiquitous signalling mechanism, occur with a tightly regulated…”
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Mitochondrial Ca2+ Homeostasis in Intact Cells by Rizzuto, Rosario, Bastianutto, Carlo, Brini, Marisa, Murgia, Marta, Pozzan, Tullio

“…Ca2+ is a key regulator not only of multiple cytosolic enzymes, but also of a variety of metabolic pathways occuring within the lumen of intracellular…”
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Subcellular Imaging of Intramitochondrial Ca2+ with Recombinant Targeted Aequorin: Significance for the Regulation of Pyruvate Dehydrogenase Activity by Rutter, Guy A., Burnett, Paul, Rizzuto, Rosario, Brini, Marisa, Murgia, Marta, Pozzan, Tullio, Tavaré, Jeremy M., Denton, Richard M.

“…Specific targeting of the recombinant, Ca2+-sensitive photoprotein, aequorin to intracellular organelles has provided new insights into the mechanisms of…”
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Plasma-membrane calcium pumps and hereditary deafness by Brini, M, Di Leva, F, Domi, T, Fedrizzi, L, Lim, D, Carafoli, E

“…In mammals, four different genes encode four PMCA (plasma-membrane Ca(2+)-ATPase) isoforms. PMCA1 and 4 are expressed ubiquitously, and PMCA2 and 3 are…”
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Intercellular adhesion molecule 1 gene polymorphisms in polymyalgia rheumatica/giant cell arteritis: association with disease risk and severity by Salvarani, C, Casali, B, Boiardi, L, Ranzi, A, Macchioni, P, Nicoli, D, Farnetti, E, Brini, M, Portioli, I

“…Intercellular adhesion molecule 1 (ICAM-1) is widely distributed in shoulder synovial membrane of active polymyalgia rheumatica (PMR) and strongly expressed in…”
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Nuclear Ca2+ concentration measured with specifically targeted recombinant aequorin by Brini, M., Murgia, M., Pasti, L., Picard, D., Pozzan, T., Rizzuto, R.

“…Activation of nuclear transcription factors, breakdown of nuclear envelope and apoptosis represent a group of nuclear events thought to be modulated by changes…”
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SERCA1 Truncated Proteins Unable to Pump Calcium Reduce the Endoplasmic Reticulum Calcium Concentration and Induce Apoptosis by Chami, Mounia, Gozuacik, Devrim, Lagorce, David, Brini, Marisa, Falson, Pierre, Peaucellier, Gérard, Pinton, Paolo, Lecoeur, Hervé, Gougeon, Marie-Lyse, le Maire, Marc, Rizzuto, Rosario, Bréchot, Christian, Paterlini-Bréchot, Patrizia

“…By pumping calcium from the cytosol to the ER, sarco/endoplasmic reticulum calcium ATPases (SERCAs) play a major role in the control of calcium signaling. We…”
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The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering by Ottolini, Denis, Calì, Tito, Negro, Alessandro, Brini, Marisa

“…DJ-1 was first identified as an oncogene. More recently, mutations in its gene have been found causative for autosomal recessive familial Parkinson disease…”
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African Sleeping Sickness in Tourists Returning from Tanzania: The First 2 Italian Cases from a Small Outbreak among European Travelers by Ripamonti, Diego, Massari, Marco, Claudio, Arici, Ermanno, Gabbi, Claudio, Farina, Brini, Maria, Capatti, Carlo, Suter, Fredy

“…A recent cluster of cases of African trypanosomiasis in humans (HAT) has been reported in tourists (most of whom were European) returning from Tanzania; we…”
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Ca2+ signalling in mitochondria: mechanism and role in physiology and pathology by Brini, Marisa

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