Search Results - "Bringmann, G."

Atroposelective Synthesis of Axially Chiral Biaryl Compounds by Bringmann, Gerhard, Price Mortimer, Anne J., Keller, Paul A., Gresser, Mary J., Garner, James, Breuning, Matthias

“…A rotationally hindered and thus stereogenic biaryl axis is the structurally and stereochemically decisive element of a steadily growing number of natural…”
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Stereoselective Total Synthesis of Axially Chiral Natural Products via Biaryl Lactones by Bringmann, Gerhard, Menche, Dirk

“…Axially chiral natural products are rewarding synthetic targets, due to their wide distribution, diverse structures, and promising bioactivities. The “lactone…”
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Molecular Phylogeny and Character Evolution of Carnivorous Plant Families in Caryophyllales - Revisited by Heubl, G., Bringmann, G., Meimberg, H.

“…Recent phylogenetic analyses based on single gene and combined data sets have substantially increased our knowledge of the phylogeny of Caryophyllales s.l.,…”
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New Natural Products from the Sponge-Derived Fungus Aspergillus niger by HIORT, J., MAKSIMENKA, K., REICHERT, M., PEROVIć-OTTSTADT, S., LIN, W. H., WRAY, V., STEUBE, K., SCHAUMANN, K., WEBER, H., PROKSCH, P., EBEL, R., MüLLER, W. E. G., BRINGMANN, G.

“…Fractionation of the EtOAc extract of a static culture of Aspergillus niger isolated from the Mediterranean sponge Axinella damicornis yielded eight secondary…”
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Murrastifoline-F:  First Total Synthesis, Atropo-Enantiomer Resolution, and Stereoanalysis of an Axially Chiral N,C-Coupled Biaryl Alkaloid by Bringmann, Gerhard, Tasler, Stefan, Endress, Heike, Kraus, Jürgen, Messer, Kim, Wohlfarth, Michael, Lobin, Wolfram

“…The first total synthesis of the Murraya alkaloid murrastifoline-F (3), an unsymmetric, N,C-bonded heterobiarylic biscarbazole, is described. Starting from the…”
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Structural Characteristics of Human Substantia Nigra Neuromelanin and Synthetic Dopamine Melanins by Double, K. L., Zecca, L., Costi, P., Mauer, M., Griesinger, C., Ito, S., Ben‐Shachar, D., Bringmann, G., Fariello, R. G., Riederer, P., Gerlach, M.

“…: Neuromelanin (NM) is a complex polymer pigment foundprimarily in the dopaminergic neurons of the human substantia nigra. Thestructure of NM is only partially…”
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Extract screening by HPLC coupled to MS–MS, NMR, and CD: a dimeric and three monomeric naphthylisoquinoline alkaloids from Ancistrocladus griffithii by Bringmann, Gerhard, Wohlfarth, Michael, Rischer, Heiko, Schlauer, Jan, Brun, Reto

“…Three new monomeric naphthylisoquinoline alkaloids, ancistrogriffines A, B, and C, and the first dimer of a 7,8′-coupled naphthylisoquinoline,…”
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Subcellular proteomics reveals neuromelanin granules to be a lysosome-related organelle by Tribl, F, Marcus, K, Meyer, H E, Bringmann, G, Gerlach, M, Riederer, P

“…The powerful combination of subcellular fractionation and protein identification by electrospray ionization tandem mass spectrometry (ESI-MS/MS) pioneered the…”
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Naphthylisoquinoline alkaloids against malaria: evaluation of the curative potentials of dioncophylline C and dioncopeltine A against Plasmodium berghei in vivo by FRANCOIS, G, TIMPERMAN, G, ELING, W, AKE ASSI, L, HOLENZ, J, BRINGMANN, G

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Proteomics of the human brain: sub-proteomes might hold the key to handle brain complexity by Tribl, F, Marcus, K, Bringmann, G, Meyer, H E, Gerlach, M, Riederer, P

“…Proteomics is a promising approach, which provides information about the expression of proteins and increasingly finds application in life science and disease…”
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Ancistrocongolines A−D, New Naphthylisoquinoline Alkaloids from Ancistrocladus congolensis by BRINGMANN, Gerhard, MESSER, Kim, BRUN, Reto, MUDOGO, Virima

“…Four new naphthylisoquinoline alkaloids, ancistrocongolines A-D (4-7) were isolated from Ancistrocladus congolensis, along with the known compound…”
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In Vitro Biotransformation of (R)- and (S)-Thalidomide:  Application of Circular Dichroism Spectroscopy to the Stereochemical Characterization of the Hydroxylated Metabolites by Meyring, Michael, Mühlbacher, Jörg, Messer, Kim, Kastner-Pustet, Nikola, Bringmann, Gerhard, Mannschreck, Albrecht, Blaschke, Gottfried

“…Circular dichroism (CD) spectroscopy was successfully used for the stereochemical characterization of the hydroxylated metabolites formed during the in vitro…”
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Molecular Phylogeny of Caryophyllidae s.l. Based on MatK Sequences with Special Emphasis on Carnivorous Taxa by Meimberg, H., Dittrich, P., Bringmann, G., Schlauer, J., Heubl, G.

“…Despite intensive morphological, chemical and cladistic studies on Caryophyllidae, the circumscription of this subclass and the interfamilial relationships are…”
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FT-Raman and NIR-SERS characterization of the antimalarial drugs chloroquine and mefloquine and their interaction with hematin by Cîntǎ-Pînzaru, S., Peica, N., Küstner, B., Schlücker, S., Schmitt, M., Frosch, T., Faber, J. H., Bringmann, G., Popp, J.

“…Raman and surface‐enhanced Raman scattering (SERS) spectroscopies were employed to probe the interaction of the antimalarial drugs chloroquine (CQ) and…”
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Antitrypanosomal naphthylisoquinoline alkaloids and related compounds by Bringmann, G, Hoerr, V, Holzgrabe, U, Stich, A

“…In view of the need to develop new drugs against human African trypanosomiasis, a series of naturally occurring naphthylisoquinoline alkaloids, axially chiral…”
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An insecticidal rocaglamide derivatives and related compounds from Aglaia odorata (Meliaceae) by Nugroho, B.W., Edrada, R.A., Wray, V., Witte, L., Bringmann, G., Gehling, M., Proksch, P.

“…Organic extracts of the twigs and leaves of Aglaia odorata yielded eight insecticidal cyclopentatetrahydrobenzofuran rocaglamide derivatives including three…”
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Biotransformation and pharmacokinetics of the antiplasmodial naphthylisoquinoline alkaloid dioncophylline A by Sieber, M., Dekant, W., Faber, J. H., Bringmann, G.

“…The biotransformation of the antiplasmodial naphthylisoquinoline alkaloid dioncophylline A by rat liver microsomes and its pharmacokinetics in male rats were…”
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Cytotoxicity of chloral-derived beta-carbolines is not specific towards neuronal nor dopaminergic cells by Storch, A, Hwang, Y-I, Bringmann, G, Feineis, D, Ott, S, Brückner, R, Schwarz, J

“…beta-Carbolines structurally related to the selective dopaminergic neurotoxin 1-methyl-4- phenylpyridinium (MPP(+)) may contribute to dopaminergic…”
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Reaction of nitroso derivatives of dinitropyrenes with sulfhydryl groups of peptides and hemoglobin in vitro and in rats by Straube, E., Völkel, W., Bringmann, G., Dekant, W.

“…Diesel engine emissions have been classified as a potential human carcinogen and may cause a variety of other health effects. Human exposure to diesel engine…”
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Stress‐related polyketide metabolism of Dioncophyllaceae and Ancistrocladaceae by Bringmann, Gerhard, Feineis, Doris

“…The discovery of a novel biosynthetic pathway to isoquinoline alkaloids is described. The naphthylisoquinoline alkaloid dioncophylline A, one of the most…”
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