Search Results - "Bringman, Timothy S."

Production and auto-induction of transforming growth factor-α in human keratinocytes by Coffey, Robert J, Derynck, Rik, Wilcox, Josiah N, Bringman, Timothy S, Goustin, A. Scott, Moses, Harold L, Pittelkow, Mark R

“…Transforming growth factor-alpha (TGF-alpha) is a polypeptide which is structurally related to epidermal growth factor (EGF) and binds to the EGF receptor…”
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Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors by Bertolini, Donald R, Nedwin, Glenn E, Bringman, Timothy S, Smith, Donna D, Mundy, Gregory R

“…When leukocytes are exposed to mitogens or antigens in vitro, they release bone-resorbing activity into the culture supernatants which can be detected by…”
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Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity by Gray, Patrick W, Aggarwal, Bharat B, Benton, Charles V, Bringman, Timothy S, Henzel, William J, Jarrett, Julie A, Leung, David W, Moffat, Barbara, Ng, Peter, Svedersky, Lloyd P, Palladino, Michael A, Nedwin, Glenn E

“…A chemically-synthesized gene and natural complementary DNA coding for human lymphotoxin were isolated and engineered for expression in Escherichia coli…”
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Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumors by DERYNCK, R, GOEDDEL, D. V, ULLRICH, A, GUTTERMAN, J. U, WILLIAMS, R. D, BRINGMAN, T. S, BERGER, W. H

“…Human tumors and tumor cell lines were analyzed for the presence of mRNA coding for transforming growth factors alpha and beta (TGF-alpha and -beta) and the…”
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Different transforming growth factor-alpha species are derived from a glycosylated and palmitoylated transmembrane precursor by Bringman, T S, Lindquist, P B, Derynck, R

“…cDNA analysis has revealed that the 50 amino acid transforming growth factor-alpha (TGF-alpha) is derived from a 160 amino acid precursor. Antibodies to…”
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Recombinant human beta-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis by Offner, H, Celnik, B, Bringman, T S, Casentini-Borocz, D, Nedwin, G E, Vandenbark, A A

“…Human placental tissue contains regulatory molecules that may prevent allo-sensitization. Recently, a 14 kDa beta-galactoside binding protein with demonstrated…”
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Expression in rat fibroblasts of a human transforming growth factor-alpha cDNA results in transformation by Rosenthal, A, Lindquist, P B, Bringman, T S, Goeddel, D V, Derynck, R

“…Acquisition of the ability to produce and respond to a growth factor may result in increased cellular proliferation and could lead to malignant transformation…”
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Cloning and Expression in Escherichia coli of the cDNA for Murine Tumor Necrosis Factor by Pennica, Diane, Hayflick, Joel S., Bringman, Timothy S., Palladino, Michael A., Goeddel, David V.

“…A murine tumor necrosis factor (MuTNF) cDNA was isolated from a cDNA library prepared by using mRNA from the murine macrophage-like cell line PU5-1.8 induced…”
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The Human Transforming Growth Factor Type α Coding Sequence is not a Direct-Acting Oncogene When Overexpressed in NIH 3T3 Cells by FINZI, E, FLEMING, T, SEGATTO, O, PENNINGTON, C. Y, BRINGMAN, T. S, DERYNCK, R, AARONSON, S. A

“…A peptide secreted by some tumor cells in vitro imparts anchorage-independent growth to normal rat kidney (NRK) cells and has been termed transforming growth…”
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Generation of antibodies and assays for transforming growth factor alpha by Lucas, C, Bringman, T S, Derynck, R

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Monoclonal antibodies to human tumor necrosis factors alpha and beta: application for affinity purification, immunoassays, and as structural probes by Bringman, T S, Aggarwal, B B

“…Monoclonal antibodies were produced against two structurally related tumor necrosis factors (TNFs), TNF-alpha (previously called tumor necrosis factor) and…”
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