Search Results - "Brillo, Valentina"
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Mitochondrial Dynamics, ROS, and Cell Signaling: A Blended Overview
Published in Life (Basel, Switzerland) (10-04-2021)“…Mitochondria are key intracellular organelles involved not only in the metabolic state of the cell, but also in several cellular functions, such as…”
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The Role of Transglutaminase 2 in Cancer: An Update
Published in International journal of molecular sciences (28-02-2024)“…Transglutaminase type 2 (TG2) is the most ubiquitously expressed and well characterized member of the transglutaminase family. It is a ubiquitous…”
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From Channels to Canonical Wnt Signaling: A Pathological Perspective
Published in International journal of molecular sciences (28-04-2021)“…Wnt signaling is an important pathway mainly active during embryonic development and controlling cell proliferation. This regulatory pathway is aberrantly…”
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Promising prognostic value of Transglutaminase type 2 and its correlation with tumor-infiltrating immune cells in skin cutaneous melanoma
Published in Cell death discovery (20-06-2022)“…Tissue Transglutaminases (TGs) are crosslinking enzymes with pleiotropic functions that have been linked to the development and progression of numerous…”
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Transglutaminase Type 2-MITF axis regulates phenotype switching in skin cutaneous melanoma
Published in Cell death & disease (28-10-2023)“…Skin cutaneous melanoma (SKCM) is the deadliest form of skin cancer due to its high heterogeneity that drives tumor aggressiveness. Melanoma plasticity…”
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Anti-VEGF therapy selects for clones resistant to glucose starvation in ovarian cancer xenografts
Published in Journal of experimental & clinical cancer research (07-08-2023)“…Genetic and metabolic heterogeneity are well-known features of cancer and tumors can be viewed as an evolving mix of subclonal populations, subjected to…”
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Transglutaminase type 2 modulates melanoma mitochondrial metabolism during phenotype switching
Published in Biochimica et biophysica acta. Bioenergetics (01-09-2024)Get full text
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Impaired Mitochondrial Metabolism And Er-Mitochondria Contact Sites Affect Signaling In Cancer Cells
Published in Biochimica et biophysica acta. Bioenergetics (01-09-2024)Get full text
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Impaired mitochondrial metabolism and ER-mitochondria contact sites affect signaling in cancer cells
Published in Biochimica et biophysica acta. Molecular basis of disease (01-12-2024)Get full text
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Mitochondrial dysfunction interferes with neural crest specification through the FoxD3 transcription factor
Published in Pharmacological research (01-02-2021)“…[Display omitted] •Mitochondria control cell fate transition via modulation of Wnt signaling and FoxD3.•Mitochondria enable Neural crest differentiation.•FoxD3…”
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Rewiring of Lipid Metabolism and Storage in Ovarian Cancer Cells after Anti-VEGF Therapy
Published in Cells (Basel, Switzerland) (09-12-2019)“…Anti-angiogenic therapy triggers metabolic alterations in experimental and human tumors, the best characterized being exacerbated glycolysis and lactate…”
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