Search Results - "Bright, Jo‐Anne"

Probabilistic genotyping software: An overview by Coble, Michael D., Bright, Jo-Anne

“…•A historical background of mixture interpretation is presented.•Probabilistic methods of interpretation are described.•Future needs of probabilistic methods…”
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A comparison of likelihood ratios obtained from EuroForMix and STRmix by Cheng, Kevin, Bleka, Øyvind, Gill, Peter, Curran, James, Bright, Jo‐Anne, Taylor, Duncan, Buckleton, John

“…Likelihood ratios (LR) differences between the probabilistic genotyping software EuroForMix and STRmix™ are examined. After considering differences in the…”
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Exploring likelihood ratios assigned for siblings of the true mixture contributor as an alternate contributor by Kelly, Hannah, Coble, Michael, Kruijver, Maarten, Wivell, Richard, Bright, Jo‐Anne

“…Relatives tend to have more DNA in common than unrelated people. The closer the biological relationship, the higher the chance of alleles being identical by…”
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The interpretation of single source and mixed DNA profiles by Taylor, Duncan, Bright, Jo-Anne, Buckleton, John

“…Abstract A method for interpreting autosomal mixed DNA profiles based on continuous modelling of peak heights is described. MCMC is applied with a model for…”
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Extending the discussion on inconsistency in forensic decisions and results by Buckleton, John, Bright, Jo‐Anne, Taylor, Duncan, Curran, James, Kalafut, Tim

“…The subject of inter‐ and intra‐laboratory inconsistency was recently raised in a commentary by Itiel Dror. We re‐visit an inter‐laboratory trial, with which…”
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A diagnosis of the primary difference between EuroForMix and STRmix by Buckleton, John, Susik, Mateusz, Curran, James M., Cheng, Kevin, Taylor, Duncan, Bright, Jo‐Anne, Kelly, Hannah, Wivell, Richard

“…There is interest in comparing the output, principally the likelihood ratio, from the two probabilistic genotyping software EuroForMix (EFM) and STRmix™. Many…”
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Using the Nondonor Distribution to Improve Communication and Inform Decision Making for Low LRs from Minor Contributors in Mixed DNA Profiles by Schuerman, Curt, Kalafut, Tim, Buchanan, Clint, Sutton, Joel, Bright, Jo‐Anne

“…The reporting of a likelihood ratio (LR) calculated from probabilistic genotyping software has become more popular since 2015 and has allowed for the use of…”
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Developmental validation of STRmix™, expert software for the interpretation of forensic DNA profiles by Bright, Jo-Anne, Taylor, Duncan, McGovern, Catherine, Cooper, Stuart, Russell, Laura, Abarno, Damien, Buckleton, John

“…Highlights • The developmental validation of STRmix™ following the 2015 SWGDAM Guidelines for the Validation of Probabilistic Genotyping Systems is described…”
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A mixed DNA profile controversy revisited by Kalafut, Tim, Pugh, Simone, Gill, Peter, Abbas, Sarah, Semaan, Marie, Mansour, Issam, Curran, James, Bright, Jo‐Anne, Hicks, Tacha, Wivell, Richard, Buckleton, John

“…Semaan et al. (J Forensic Res, 2020, 11, 453) discuss a mock case “where eight different individuals [P1 through P8] could not be excluded in a mixed DNA…”
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The Probabilistic Genotyping Software STRmix: Utility and Evidence for its Validity by Buckleton, John S., Bright, Jo‐Anne, Gittelson, Simone, Moretti, Tamyra R., Onorato, Anthony J., Bieber, Frederick R., Budowle, Bruce, Taylor, Duncan A.

“…Forensic DNA interpretation is transitioning from manual interpretation based usually on binary decision‐making toward computer‐based systems that model the…”
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Modeling allelic analyte signals for aSTRs in NGS DNA profiles by Cheng, Kevin, Lin, Meng‐Han, Moreno, Lilliana, Skillman, Jessica, Hickey, Stephanie, Cuenca, Daniela, Hudlow, William R., Just, Rebecca, Bright, Jo‐Anne, Buckleton, John, Curran, James M.

“…We describe an adaption of Bright et al.’s work modeling peak height variability in CE‐DNA profiles to the modeling of allelic aSTR (autosomal short tandem…”
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Developing allelic and stutter peak height models for a continuous method of DNA interpretation by Bright, Jo-Anne, Taylor, Duncan, Curran, James M, Buckleton, John S

“…Abstract Traditional forensic DNA interpretation methods are restricted as they are unable to deal completely with complex low level or mixed DNA profiles…”
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Internal validation of STRmix™ for the interpretation of single source and mixed DNA profiles by Moretti, Tamyra R, Just, Rebecca S, Kehl, Susannah C, Willis, Leah E, Buckleton, John S, Bright, Jo-Anne, Taylor, Duncan A, Onorato, Anthony J

“…Abstract The interpretation of DNA evidence can entail analysis of challenging STR typing results. Genotypes inferred from low quality or quantity specimens,…”
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A Practical Guide for the Formulation of Propositions in the Bayesian Approach to DNA Evidence Interpretation in an Adversarial Environment by Gittelson, Simone, Kalafut, Tim, Myers, Steven, Taylor, Duncan, Hicks, Tacha, Taroni, Franco, Evett, Ian W., Bright, Jo-Anne, Buckleton, John

“…The interpretation of complex DNA profiles is facilitated by a Bayesian approach. This approach requires the development of a pair of propositions: one aligned…”
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Comparison of the performance of different models for the interpretation of low level mixed DNA profiles by Bille, Todd W., Weitz, Steven M., Coble, Michael D., Buckleton, John, Bright, Jo-Anne

“…DNA analyses from forensic casework samples commonly result in complex DNA profiles. Often, these profiles consist of multiple contributors and display…”
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Application of Random Match Probability Calculations to Mixed STR Profiles by Bille, Todd, Bright, Jo-Anne, Buckleton, John

“…Mixed DNA profiles are being encountered more frequently as laboratories analyze increasing amounts of touch evidence. If it is determined that an individual…”
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The effect of the uncertainty in the number of contributors to mixed DNA profiles on profile interpretation by Bright, Jo-Anne, Curran, James M, Buckleton, John S

“…Highlights • The correct number of contributors to a profile is always unknown but a reasonable assignment can often be made, often by counting alleles. •…”
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The effect of a user selected number of contributors within the LR assignment by Kelly, Hannah, Bright, Jo-Anne, Kruijver, Maarten, Taylor, Duncan, Buckleton, John

“…The assignment of the number of contributors (N) to a forensic DNA profile is undertaken as part of the interpretation process. There is no requirement for N…”
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Implementation and validation of an improved allele specific stutter filtering method for electropherogram interpretation by Kalafut, Tim, Schuerman, Curt, Sutton, Joel, Faris, Tom, Armogida, Luigi, Bright, Jo-Anne, Buckleton, John, Taylor, Duncan

“…•Novel implementation of allele specific stutter filtering for electropherograms.•Combined stutter peaks have additive values for forward and back stutter…”
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Exploring the advantages of amplifying the entire extract versus splitting the extract and interpreting replicates using a continuous model of interpretation by Bille, Todd, Coble, Michael D., Bright, Jo-Anne

“…Previous studies examining whether splitting the DNA extract for replicate amplification versus maximizing the template available for a 'one-shot'…”
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