Search Results - "Brigham, Christopher J."
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Solvent production by engineered Ralstonia eutropha: channeling carbon to biofuel
Published in Applied microbiology and biotechnology (01-06-2018)“…Microbial production of solvents like acetone and butanol was a couple of the first industrial fermentation processes to gain global importance. These solvents…”
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Lipid and fatty acid metabolism in Ralstonia eutropha: relevance for the biotechnological production of value-added products
Published in Applied microbiology and biotechnology (01-02-2014)“…Lipid and fatty acid metabolism has been well studied in model microbial organisms like Escherichia coli and Bacillus subtilis. The major precursor of fatty…”
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Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by Ralstonia eutropha in high cell density palm oil fermentations
Published in Biotechnology and bioengineering (01-01-2012)“…Improved production costs will accelerate commercialization of polyhydroxyalkanoate (PHA) polymer and PHA‐based products. Plant oils are considered favorable…”
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Studies on the production of branched-chain alcohols in engineered Ralstonia eutropha
Published in Applied microbiology and biotechnology (01-10-2012)“…Wild-type Ralstonia eutropha H16 produces polyhydroxybutyrate (PHB) as an intracellular carbon storage material during nutrient stress in the presence of…”
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Biosynthesis and characterization of polyhydroxyalkanoate containing high 3-hydroxyhexanoate monomer fraction from crude palm kernel oil by recombinant Cupriavidus necator
Published in Bioresource technology (01-10-2012)“…[Display omitted] ► 3HHx content of 70mol% was produced using CPKO at a concentration of 2.5g/L. ► Time profile demonstrated high PHA content at the early…”
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Characterization of an extracellular lipase and its chaperone from Ralstonia eutropha H16
Published in Applied microbiology and biotechnology (01-03-2013)“…Lipase enzymes catalyze the reversible hydrolysis of triacylglycerol to fatty acids and glycerol at the lipid–water interface. The metabolically versatile…”
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Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production
Published in Applied microbiology and biotechnology (01-03-2012)“…The first biosynthetic system for lactate (LA)-based polyesters was previously created in recombinant Escherichia coli (Taguchi et al. 2008 ). Here, we have…”
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Untargeted metabolomics analysis of Ralstonia eutropha during plant oil cultivations reveals the presence of a fucose salvage pathway
Published in Scientific reports (12-07-2021)“…Process engineering of biotechnological productions can benefit greatly from comprehensive analysis of microbial physiology and metabolism. Ralstonia eutropha…”
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Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P(HB-co-HHx)) from butyrate using engineered Ralstonia eutropha
Published in Applied microbiology and biotechnology (01-06-2014)“…Polyhydroxyalkanoates (PHAs), a promising family of bio-based polymers, are considered to be alternatives to traditional petroleum-based plastics. Copolymers…”
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Whole-Genome Microarray and Gene Deletion Studies Reveal Regulation of the Polyhydroxyalkanoate Production Cycle by the Stringent Response in Ralstonia eutropha H16
Published in Applied and Environmental Microbiology (01-11-2012)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Elucidation of β-Oxidation Pathways in Ralstonia eutropha H16 by Examination of Global Gene Expression
Published in Journal of Bacteriology (01-10-2010)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Optimization of growth media components for polyhydroxyalkanoate (PHA) production from organic acids by Ralstonia eutropha
Published in Applied microbiology and biotechnology (01-08-2010)“…We employed systematic mixture analysis to determine optimal levels of acetate, propionate, and butyrate for cell growth and polyhydroxyalkanoate (PHA)…”
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Purification of Polyhydroxybutyrate Synthase from Its Native Organism, Ralstonia eutropha: Implications for the Initiation and Elongation of Polymer Formation in Vivo
Published in Biochemistry (Easton) (20-03-2012)“…Class I polyhydroxybutyrate (PHB) synthase (PhaC) from Ralstonia eutropha catalyzes the formation of PHB from (R)-3-hydroxybutyryl-CoA, ultimately resulting in…”
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Experimental evolution and gene knockout studies reveal AcrA-mediated isobutanol tolerance in Ralstonia eutropha
Published in Journal of bioscience and bioengineering (01-07-2016)“…Isobutanol (IBT) has attracted much attention from researchers as a next generation drop-in biofuel. Ralstonia eutropha is a gram-negative bacterium which…”
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Characterization of the Highly Active Polyhydroxyalkanoate Synthase of Chromobacterium sp. Strain USM2
Published in Applied and Environmental Microbiology (01-05-2011)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Characterization and modification of enzymes in the 2-ketoisovalerate biosynthesis pathway of Ralstonia eutropha H16
Published in Applied microbiology and biotechnology (01-01-2015)“…2-Ketoisovalerate is an important cellular intermediate for the synthesis of branched-chain amino acids as well as other important molecules, such as…”
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Application of a non-halogenated solvent, methyl ethyl ketone (MEK) for recovery of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(HB-co-HV)] from bacterial cells
Published in Biotechnology and bioprocess engineering (01-04-2015)“…Conventional solvent-based methods are still the most practical approaches for recovery of polyhydroxyalkanoate (PHA) polymer from cellular biomass, even…”
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Synthetic biology toolkit of Ralstonia eutropha (Cupriavidus necator)
Published in Applied microbiology and biotechnology (01-12-2024)“…Synthetic biology encompasses many kinds of ideas and techniques with the common theme of creating something novel. The industrially relevant microorganism,…”
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Mechanical and biological properties of chitin/polylactide (PLA)/hydroxyapatite (HAP) composites cast using ionic liquid solutions
Published in International journal of biological macromolecules (15-05-2020)“…•Ionic liquid (IL) was used for co-dissolution of polymers like chitin, PLA and nHAP.•Thermal and spectroscopical analyses show well-blended composite…”
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