Search Results - "Briggs, Sherri B."
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The Role of Nonmuscle Myosin II in Polydrug Memories and Memory Reconsolidation
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-09-2018)“…Using pharmacologic and genetic approaches targeting actin or the actin-driving molecular motor, nonmuscle myosin II (NMII), we previously discovered an…”
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The Actin Cytoskeleton as a Therapeutic Target for the Prevention of Relapse to Methamphetamine Use
Published in CNS & neurological disorders drug targets (01-01-2015)“…A high rate of relapse is a defining characteristic of substance use disorder for which few treatments are available. Exposure to environmental cues associated…”
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Don't ignore the middle: Distinct mnemonic functions of intermediate hippocampus
Published in Hippocampus (01-10-2024)“…The dorsal region of the hippocampus (dHC) mediates many of the mnemonic functions traditionally associated with the hippocampus proper, such as spatial and…”
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Inhibiting Ventral Hippocampal NMDA Receptors and "Arc" Increases Energy Intake in Male Rats
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-06-2021)“…Research into the neural mechanisms that underlie higher-order cognitive control of eating behavior suggests that ventral hippocampal (vHC) neurons, which are…”
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Basolateral amygdala corticotropin releasing factor receptor 2 interacts with nonmuscle myosin II to destabilize memory in males
Published in Neurobiology of learning and memory (01-12-2023)“…Preclinical studies show that inhibiting the actin motor ATPase nonmuscle myosin II (NMII) with blebbistatin (Blebb) in the basolateral amgydala (BLA)…”
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Cocaine self‐administration induces changes in synaptic transmission and plasticity in ventral hippocampus
Published in Addiction biology (01-03-2017)“…Allowing rats extended access to cocaine self‐administration is thought to recapitulate several key aspects of cocaine addiction in humans. Understanding the…”
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Nonmuscle myosin II inhibition disrupts methamphetamine-associated memory in females and adolescents
Published in Neurobiology of learning and memory (01-03-2017)“…Memories associated with drug use can trigger strong motivation for the drug, which increases relapse vulnerability in substance use disorder (SUD). Currently…”
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Memory Disrupting Effects of Nonmuscle Myosin II Inhibition Depend on the Class of Abused Drug and Brain Region
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-02-2017)“…Depolymerizing actin in the amygdala through nonmuscle myosin II inhibition (NMIIi) produces a selective, lasting, and retrieval-independent disruption of the…”
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Cyclin-Dependent Kinase Inhibitor 1a (p21) Modulates Response to Cocaine and Motivated Behaviors
Published in The Journal of pharmacology and experimental therapeutics (01-04-2016)“…This study investigated the functional role of cyclin-dependent kinase inhibitor 1a (Cdkn1a or p21) in cocaine-induced responses using a knockout mouse model…”
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Nonmuscle myosin IIB as a therapeutic target for the prevention of relapse to methamphetamine use
Published in Molecular psychiatry (01-05-2016)“…Memories associated with drug use increase vulnerability to relapse in substance use disorder (SUD), and there are no pharmacotherapies for the prevention of…”
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