Search Results - "Briggs, G. A."

Structure and assembly of the Ebola virus nucleocapsid by Wan, William, Kolesnikova, Larissa, Clarke, Mairi, Koehler, Alexander, Noda, Takeshi, Becker, Stephan, Briggs, John A. G.

“…Application of cryo-electron tomography and subtomogram averaging to determine the structure of the Ebola virus nucleocapsid within intact viruses and…”
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Structural biology in situ—the potential of subtomogram averaging by Briggs, John AG

“…► Subtomogram averaging from cryo-electron tomography data resolves structures in situ. ► Resolutions of 2–4nm have been obtained in situ for a number of…”
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Machine learning enables completely automatic tuning of a quantum device faster than human experts by Moon, H., Lennon, D. T., Kirkpatrick, J., van Esbroeck, N. M., Camenzind, L. C., Yu, Liuqi, Vigneau, F., Zumbühl, D. M., Briggs, G. A. D., Osborne, M. A., Sejdinovic, D., Laird, E. A., Ares, N.

“…Variability is a problem for the scalability of semiconductor quantum devices. The parameter space is large, and the operating range is small. Our statistical…”
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An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation by Schur, Florian K. M., Obr, Martin, Hagen, Wim J. H., Wan, William, Jakobi, Arjen J., Kirkpatrick, Joanna M., Sachse, Carsten, Kräusslich, Hans-Georg, Briggs, John A. G.

“…Immature HIV-1 assembles at and buds from the plasma membrane before proteolytic cleavage of the viral Gag polyprotein induces structural maturation…”
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Nuclear Pore Scaffold Structure Analyzed by Super-Resolution Microscopy and Particle Averaging by Szymborska, Anna, de Marco, Alex, Daigle, Nathalie, Cordes, Volker C., Briggs, John A. G., Ellenberg, Jan

“…Much of life's essential molecular machinery consists of large protein assemblies that currently pose challenges for structure determination. A prominent…”
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A coherent nanomechanical oscillator driven by single-electron tunnelling by Wen, Yutian, Ares, N., Schupp, F. J., Pei, T., Briggs, G. A. D., Laird, E. A.

“…A single-electron transistor embedded in a nanomechanical resonator represents an extreme limit of electron–phonon coupling. While it allows fast and sensitive…”
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Resonant Optomechanics with a Vibrating Carbon Nanotube and a Radio-Frequency Cavity by Ares, N, Pei, T, Mavalankar, A, Mergenthaler, M, Warner, J H, Briggs, G A D, Laird, E A

“…In an optomechanical setup, the coupling between cavity and resonator can be increased by tuning them to the same frequency. We study this interaction between…”
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A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0 by Zivanov, Jasenko, Otón, Joaquín, Ke, Zunlong, von Kügelgen, Andriko, Pyle, Euan, Qu, Kun, Morado, Dustin, Castaño-Díez, Daniel, Zanetti, Giulia, Bharat, Tanmay A M, Briggs, John A G, Scheres, Sjors H W

“…We present a new approach for macromolecular structure determination from multiple particles in electron cryo-tomography (cryo-ET) data sets. Whereas existing…”
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Minimal Tags for Rapid Dual-Color Live-Cell Labeling and Super-Resolution Microscopy by Nikić, Ivana, Plass, Tilman, Schraidt, Oliver, Szymański, Jędrzej, Briggs, John A. G., Schultz, Carsten, Lemke, Edward A.

“…The growing demands of advanced fluorescence and super‐resolution microscopy benefit from the development of small and highly photostable fluorescent probes…”
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Endocytic sites mature by continuous bending and remodeling of the clathrin coat by Avinoam, Ori, Schorb, Martin, Beese, Carsten J., Briggs, John A. G., Kaksonen, Marko

“…During clathrin-mediated endocytosis (CME), plasma membrane regions are internalized to retrieve extracellular molecules and cell surface components. Whether…”
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Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike by Qu, Kun, Chen, Qiuluan, Ciazynska, Katarzyna A, Liu, Banghui, Zhang, Xixi, Wang, Jingjing, He, Yujie, Guan, Jiali, He, Jun, Liu, Tian, Zhang, Xiaofei, Carter, Andrew P, Xiong, Xiaoli, Briggs, John A. G

“…The spike (S) protein of SARS-CoV-2 has been observed in three distinct pre-fusion conformations: locked, closed and open. Of these, the function of the locked…”
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Measuring the Thermodynamic Cost of Timekeeping by Pearson, A. N., Guryanova, Y., Erker, P., Laird, E. A., Briggs, G. A. D., Huber, M., Ares, N.

“…All clocks, in some form or another, use the evolution of nature toward higher entropy states to quantify the passage of time. Because of the statistical…”
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Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins by Erlendsson, Simon, Morado, Dustin R., Cullen, Harrison B., Feschotte, Cedric, Shepherd, Jason D., Briggs, John A. G.

“…Arc , a neuronal gene that is critical for synaptic plasticity, originated through the domestication of retrotransposon Gag genes and mediates intercellular…”
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Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography by Bharat, Tanmay A. M., Noda, Takeshi, Riches, James D., Kraehling, Verena, Kolesnikova, Larissa, Becker, Stephan, Kawaoka, Yoshihiro, Briggs, John A. G.

“…Ebola virus is a highly pathogenic filovirus causing severe hemorrhagic fever with high mortality rates. It assembles heterogenous, filamentous, enveloped…”
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Cryo-electron tomography of Marburg virus particles and their morphogenesis within infected cells by Bharat, Tanmay A M, Riches, James D, Kolesnikova, Larissa, Welsch, Sonja, Krähling, Verena, Davey, Norman, Parsy, Marie-Laure, Becker, Stephan, Briggs, John A G

“…Several major human pathogens, including the filoviruses, paramyxoviruses, and rhabdoviruses, package their single-stranded RNA genomes within helical…”
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Efficiently measuring a quantum device using machine learning by Lennon, D. T., Moon, H., Camenzind, L. C., Yu, Liuqi, Zumbühl, D. M., Briggs, G. A .D., Osborne, M. A., Laird, E. A., Ares, N.

“…Scalable quantum technologies such as quantum computers will require very large numbers of quantum devices to be characterised and tuned. As the number of…”
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Structures and distributions of SARS-CoV-2 spike proteins on intact virions by Ke, Zunlong, Oton, Joaquin, Qu, Kun, Cortese, Mirko, Zila, Vojtech, McKeane, Lesley, Nakane, Takanori, Zivanov, Jasenko, Neufeldt, Christopher J., Cerikan, Berati, Lu, John M., Peukes, Julia, Xiong, Xiaoli, Kräusslich, Hans-Georg, Scheres, Sjors H. W., Bartenschlager, Ralf, Briggs, John A. G.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virions are surrounded by a lipid bilayer from which spike (S) protein trimers protrude 1 …”
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Radio-frequency optomechanical characterization of a silicon nitride drum by Pearson, A. N., Khosla, K. E., Mergenthaler, M., Briggs, G. A. D., Laird, E. A., Ares, N.

“…On-chip actuation and readout of mechanical motion is key to characterize mechanical resonators and exploit them for new applications. We capacitively couple a…”
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Virological Synapse-Mediated Spread of Human Immunodeficiency Virus Type 1 between T Cells Is Sensitive to Entry Inhibition by MARTIN, Nicola, WELSCH, Sonja, JOLLY, Clare, BRIGGS, John A. G, VAUX, David, SATTENTAU, Quentin J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The structure of the COPII transport-vesicle coat assembled on membranes by Zanetti, Giulia, Prinz, Simone, Daum, Sebastian, Meister, Annette, Schekman, Randy, Bacia, Kirsten, Briggs, John A G

“…Coat protein complex II (COPII) mediates formation of the membrane vesicles that export newly synthesised proteins from the endoplasmic reticulum. The inner…”
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