Search Results - "Brierley, Catherine H"

Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation by Burchell, B, Brierley, C H, Rance, D

“…Several human liver UDP-Glucuronosyltransferases (UGTs) have been cloned and the cDNAs expressed in heterologous cell lines. This technological advance has…”
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Drug Glucuronidation by Human Renal UDP-Glucuronosyltransferases by McGurk, Karen A, Brierley, Catherine H, Burchell, Brian

“…The UDP-glucuronosyltransferases catalyse the conjugation of glucuronic acid to a wide variety of endobiotics and xenobiotics, representing one of the major…”
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Human UDP-glucuronosyl transferases: chemical defence, jaundice and gene therapy by Brierley, C H, Burchell, B

“…Human UDP-glucuronosyltransferases (UDPGTs) are a family of enzymes which detoxify many hundreds of compounds by their conjugation to glucuronic acid,…”
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Mechanisms of maternal aneuploidy : FISH analysis of oocytes and polar bodies in patients undergoing assisted conception by MAHMOOD, R, BRIERLEY, C. H, FAED, M. J. W, MILLS, J. A, DELHANTY, J. D. A

“…We have examined unfertilised oocytes and their first polar bodies (PBs) to determine the way in which the frequency of whole chromosome imbalance compares…”
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Drug Glucuronidation by Human Renal UDP-Glucuronosyltransferases 11The nomenclature used in this manuscript is based on published recommendations and is to be defined by the position of the variable exon within the gene complex [45]. The position of the specific isoform formerly known as HlugP4 or UGT1∗02 has yet to be resolved. As such, the nomenclature for this isoform will be stated as UGT1A8/9 by McGurk, Karen A, Brierley, Catherine H, Burchell, Brian

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Regulation of the human bilirubin UDP-glucuronosyltransferase gene by Brierley, Catherine H., Senafi, Sahidan Bin, Clarke, Douglas, Hsu, Mei-Hui, Johnson, Eric F., Burchell, Brian

“…The human UGT1 gene is a single copy gene consisting of four common exons and more than 13 variable exons which span more than 200 kb of the human genome. A…”
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