Search Results - "Briem, Eirikur"

Increased methylation variation in epigenetic domains across cancer types by Irizarry, Rafael A, Feinberg, Andrew P, Hansen, Kasper Daniel, Timp, Winston, Bravo, Héctor Corrada, Sabunciyan, Sarven, Langmead, Benjamin, McDonald, Oliver G, Wen, Bo, Wu, Hao, Liu, Yun, Diep, Dinh, Briem, Eirikur, Zhang, Kun

“…Andrew Feinberg and colleagues report whole-genome bisulfite sequencing of three colon cancers and matched normal tissue and two adenomatous polyps. The…”
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EGFR Signal-Network Reconstruction Demonstrates Metabolic Crosstalk in EMT by Choudhary, Kumari Sonal, Rohatgi, Neha, Halldorsson, Skarphedinn, Briem, Eirikur, Gudjonsson, Thorarinn, Gudmundsson, Steinn, Rolfsson, Ottar

“…Epithelial to mesenchymal transition (EMT) is an important event during development and cancer metastasis. There is limited understanding of the metabolic…”
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Detection of phenotype‐specific therapeutic vulnerabilities in breast cells using a CRISPR loss‐of‐function screen by Barkovskaya, Anna, Goodwin, Craig M., Seip, Kotryna, Hilmarsdottir, Bylgja, Pettersen, Solveig, Stalnecker, Clint, Engebraaten, Olav, Briem, Eirikur, Der, Channing J., Moestue, Siver A., Gudjonsson, Thorarinn, Mælandsmo, Gunhild M., Prasmickaite, Lina

“…Cellular phenotype plasticity between the epithelial and mesenchymal states has been linked to metastasis and heterogeneous responses to cancer therapy, and…”
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Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions by Wen, Bo, Wu, Hao, Loh, Yuin-Han, Briem, Eirikur, Daley, George Q, Feinberg, Andrew P

“…The organization of higher order chromatin is an emerging epigenetic mechanism for understanding development and disease. We and others have previously…”
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Expression of ncRNAs on the DLK1-DIO3 Locus Is Associated With Basal and Mesenchymal Phenotype in Breast Epithelial Progenitor Cells by Budkova, Zuzana, Sigurdardottir, Anna Karen, Briem, Eirikur, Bergthorsson, Jon Thor, Sigurdsson, Snævar, Magnusson, Magnus Karl, Traustadottir, Gunnhildur Asta, Gudjonsson, Thorarinn, Hilmarsdottir, Bylgja

“…Epithelial-to-mesenchymal transition (EMT) and its reversed process mesenchymal-to-epithelial transition (MET) play a critical role in epithelial plasticity…”
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Epithelial Plasticity During Human Breast Morphogenesis and Cancer Progression by Ingthorsson, Saevar, Briem, Eirikur, Bergthorsson, Jon Thor, Gudjonsson, Thorarinn

“…Understanding the complex events leading to formation of an epithelial-based organ such as the breast requires a detailed insight into the crosstalk between…”
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Common DNA methylation alterations in multiple brain regions in autism by Ladd-Acosta, C, Hansen, K D, Briem, E, Fallin, M D, Kaufmann, W E, Feinberg, A P

“…Autism spectrum disorders (ASD) are increasingly common neurodevelopmental disorders defined clinically by a triad of features including impairment in social…”
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Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study by Montano, Carolina, Taub, Margaret A, Jaffe, Andrew, Briem, Eirikur, Feinberg, Jason I, Trygvadottir, Rakel, Idrizi, Adrian, Runarsson, Arni, Berndsen, Birna, Gur, Ruben C, Moore, Tyler M, Perry, Rodney T, Fugman, Doug, Sabunciyan, Sarven, Yolken, Robert H, Hyde, Thomas M, Kleinman, Joel E, Sobell, Janet L, Pato, Carlos N, Pato, Michele T, Go, Rodney C, Nimgaonkar, Vishwajit, Weinberger, Daniel R, Braff, David, Gur, Raquel E, Fallin, Margaret Daniele, Feinberg, Andrew P

“…DNA methylation may play an important role in schizophrenia (SZ), either directly as a mechanism of pathogenesis or as a biomarker of risk. To scan genome-wide…”
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Application of the D492 Cell Lines to Explore Breast Morphogenesis, EMT and Cancer Progression in 3D Culture by Briem, Eirikur, Ingthorsson, Saevar, Traustadottir, Gunnhildur Asta, Hilmarsdottir, Bylgja, Gudjonsson, Thorarinn

“…The human female breast gland is composed of branching epithelial ducts that extend from the nipple towards the terminal duct lobular units (TDLUs), which are…”
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Abstract 3435: Profiling miRNAs in breast epithelial progenitor cells during branching morphogenesis and EMT in 3D culture by Briem, Eirikur, Hilmarsdottir, Bylgja, Budkova, Zuzana, Ingthorsson, Saevar, Magnusson, Magnus K., Gudjonsson, Thorarinn

“…Abstract In this study we investigate the role of miRNA-203a in branching morphogenesis and epithelial to mesenchymal transition (EMT) in breast cell lines…”
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Abstract B08: Expression of noncoding RNAs on the DLK1-DIO1 locus in EMT and breast cancer by Hilmarsdottir, Bylgja, Briem, Eirikur, Bergthorsson, Jon Thor, Gudjonsson, Thorarinn, Magnusson, Magnus Karl

“…Abstract The DLK1-DIO3 locus contains three paternally expressed protein-coding genes and maternally expressed non-protein coding genes, including the lncRNA…”
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Functional Role of the microRNA-200 Family in Breast Morphogenesis and Neoplasia by Hilmarsdottir, Bylgja, Briem, Eirikur, Bergthorsson, Jon Thor, Magnusson, Magnus Karl, Gudjonsson, Thorarinn

“…Branching epithelial morphogenesis is closely linked to epithelial-to-mesenchymal transition (EMT), a process important in normal development and cancer…”
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Inhibition of PTP1B disrupts cell–cell adhesion and induces anoikis in breast epithelial cells by Hilmarsdottir, Bylgja, Briem, Eirikur, Halldorsson, Skarphedinn, Kricker, Jennifer, Ingthorsson, Sævar, Gustafsdottir, Sigrun, Mælandsmo, Gunhild M, Magnusson, Magnus K, Gudjonsson, Thorarinn

“…Protein tyrosine phosphatase 1B (PTP1B) is a well-known inhibitor of insulin signaling pathways and inhibitors against PTP1B are being developed as promising…”
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MicroRNA-200c-141 and ∆Np63 are required for breast epithelial differentiation and branching morphogenesis by Hilmarsdóttir, Bylgja, Briem, Eirikur, Sigurdsson, Valgardur, Franzdóttir, Sigrídur Rut, Ringnér, Markus, Arason, Ari Jon, Bergthorsson, Jon Thor, Magnusson, Magnus Karl, Gudjonsson, Thorarinn

“…The epithelial compartment of the breast contains two lineages, the luminal- and the myoepithelial cells. D492 is a breast epithelial cell line with stem cell…”
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MiR-203a is differentially expressed during branching morphogenesis and EMT in breast progenitor cells and is a repressor of peroxidasin by Briem, Eirikur, Budkova, Zuzana, Sigurdardottir, Anna Karen, Hilmarsdottir, Bylgja, Kricker, Jennifer, Timp, Winston, Magnusson, Magnus Karl, Traustadottir, Gunnhildur Asta, Gudjonsson, Thorarinn

“…MicroRNAs regulate developmental events such as branching morphogenesis, epithelial to mesenchymal transition (EMT) and its reverse process mesenchymal to…”
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