Search Results - "Briedé, Jacob J."

Oxidative stress in healthy pregnancy and preeclampsia is linked to chronic inflammation, iron status and vascular function by Mannaerts, Dominique, Faes, Ellen, Cos, Paul, Briedé, Jacob J, Gyselaers, Wilfried, Cornette, Jerome, Gorbanev, Yury, Bogaerts, Annemie, Spaanderman, Marc, Van Craenenbroeck, Emeline, Jacquemyn, Yves

“…During normal pregnancy, placental oxidative stress (OS) is present during all three trimesters and is necessary to obtain normal cell function. However, if OS…”
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Gene expression profiling in colon of mice exposed to food additive titanium dioxide (E171) by Proquin, Héloïse, Jetten, Marlon J., Jonkhout, Marloes C.M., Garduño-Balderas, Luis G., Briedé, Jacob J., de Kok, Theo M., Chirino, Yolanda I., van Loveren, Henk

“…Dietary factors that may influence the risks of colorectal cancer, including specific supplements, are under investigation. Previous studies showed the…”
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Citrulline a more suitable substrate than arginine to restore NO production and the microcirculation during endotoxemia by Wijnands, Karolina A P, Vink, Hans, Briedé, Jacob J, van Faassen, Ernst E, Lamers, Wouter H, Buurman, Wim A, Poeze, Martijn

“…Impaired microcirculation during endotoxemia correlates with a disturbed arginine-nitric oxide (NO) metabolism and is associated with deteriorating organ…”
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Elevated oxidative stress in patients with congenital heart disease and the effect of cyanosis: a meta-analysis by Vanreusel, Inne, Taeymans, Jan, Van Craenenbroeck, Emeline, Segers, Vincent F M, Van Berendoncks, An, Briedé, Jacob J, Hens, Wendy

“…Oxidative stress is an important pathophysiological mechanism in the development of numerous cardiovascular disorders. To improve therapy and preventive…”
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Microcirculatory Function during Endotoxemia-A Functional Citrulline-Arginine-NO Pathway and NOS3 Complex Is Essential to Maintain the Microcirculation by Wijnands, Karolina A P, Meesters, Dennis M, Vandendriessche, Benjamin, Briedé, Jacob J, van Eijk, Hans M H, Brouckaert, Peter, Cauwels, Anje, Lamers, Wouter H, Poeze, Martijn

“…Competition for the amino acid arginine by endothelial nitric-oxide synthase (NOS3) and (pro-)inflammatory NO-synthase (NOS2) during endotoxemia appears…”
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Transcriptome changes in undifferentiated Caco-2 cells exposed to food-grade titanium dioxide (E171): contribution of the nano- and micro- sized particles by Proquin, Héloïse, Jonkhout, Marloes C. M., Jetten, Marlon J., van Loveren, Henk, de Kok, Theo M., Briedé, Jacob J.

“…The food additive titanium dioxide (TiO 2 ), or E171, is a white food colorant. Recent studies showed after E171 ingestion a significantly increased number of…”
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Pathogenetic role of endothelial nitric oxide synthase uncoupling during lung ischaemia–reperfusion injury by Gielis, Jan F., Quirynen, Laurent, Briedé, Jacob J., Roelant, Ella, Cos, Paul, Van Schil, Paul E.Y.

“…Abstract OBJECTIVES: Ischaemia–reperfusion injury is a necessary part of organ transplantation and a key determinant of both acute and chronic graft failure…”
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Improved Preventive Effects of Combined Bioactive Compounds Present in Different Blueberry Varieties as Compared to Single Phytochemicals by van Breda, Simone G J, Briedé, Jacob J, de Kok, Theo M C M

“…Blueberries contain many different phytochemicals which might be responsible for their disease preventive properties. In a previously conducted human dietary…”
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Transcriptomics analysis reveals new insights in E171-induced molecular alterations in a mouse model of colon cancer by Proquin, Héloïse, Jetten, Marlon J., Jonkhout, Marloes C. M., Garduño-Balderas, Luis Guillermo, Briedé, Jacob J., de Kok, Theo M., van Loveren, Henk, Chirino, Yolanda I.

“…Titanium dioxide as a food additive (E171) has been demonstrated to facilitate growth of chemically induced colorectal tumours in vivo and induce…”
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Radical mechanisms in nitrosamine- and nitrosamide-induced whole-genome gene expression modulations in Caco-2 cells by Hebels, Dennie G A J, Briedé, Jacob J, Khampang, Roongnapa, Kleinjans, Jos C S, de Kok, Theo M C M

“…N-nitroso compounds (NOCs) may be implicated in human colon carcinogenesis, but the toxicological mechanisms involved have not been elucidated. Because it was…”
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Longitudinal quantification of radical bursts during pulmonary ischaemia and reperfusion by Gielis, Jan F., Boulet, Gaëlle A., Briedé, Jacob J., Horemans, Tessa, Debergh, Tom, Kussé, Max, Cos, Paul, Van Schil, Paul E.Y.

“…OBJECTIVES Pulmonary ischaemia–reperfusion injury (IRI) is associated with several life-threatening pulmonary disorders, and may severely compromise the…”
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The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice by Nabben, Miranda, Hoeks, Joris, Briedé, Jacob J., Glatz, Jan F.C., Moonen-Kornips, Esther, Hesselink, Matthijs K.C., Schrauwen, Patrick

“…Uncoupling protein 3 (UCP3) is suggested to protect mitochondria against aging and lipid-induced damage, possibly via modulation of reactive oxygen species…”
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Intrauterine exposure to flavonoids modifies antioxidant status at adulthood and decreases oxidative stress-induced DNA damage by Vanhees, Kimberly, van Schooten, Frederik J., van Waalwijk van Doorn-Khosrovani, Sahar Barjesteh, van Helden, Stefan, Munnia, Armelle, Peluso, Marco, Briedé, Jacob J., Haenen, Guido R.M.M., Godschalk, Roger W.L.

“…Maternal intake of flavonoids, known for their antioxidant properties, may affect the offspring's susceptibility to developing chronic diseases at adult age,…”
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Circulating Reactive Oxygen Species in Adults with Congenital Heart Disease by Vanreusel, Inne, Vermeulen, Dorien, Goovaerts, Inge, Stoop, Tibor, Ectors, Bert, Cornelis, Jacky, Hens, Wendy, de Bliek, Erwin, Heuten, Hilde, Van Craenenbroeck, Emeline M, Van Berendoncks, An, Segers, Vincent F M, Briedé, Jacob J

“…Oxidative stress is an important pathophysiological mechanism in the development of numerous cardiovascular disorders, but few studies have examined the levels…”
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The contribution of α-dicarbonyl compound dependent radical formation to the antiseptic effect of honey by Henatsch, Darius, den Hartog, Gertjan J.M., Duijvestijn, Adriaan M., Wolffs, Petra F., Phielix, Esther, Stokroos, Robert J., Briedé, Jacob J.

“…[Display omitted] •α-oxoaldehydes methylglyoxal, glyoxal and 3-deoxyglucosone are present in different honeys in varying concentrations.•Methylglyoxal and…”
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A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases by Briedé, Jacob J., Deferme, Lize, Wolters, Jarno E.J., Claessen, Sandra M.H., van den Beucken, Twan, Wagner, Richard J., van Breda, Simone G., Kleinjans, Jos C.S.

“…Regulation of DNA methylation plays a crucial role in biological processes and carcinogenesis. The formation of 5-hydroxymethylcytosine (5hmC) by oxidation of…”
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Incomplete protection of genetic integrity of mature spermatozoa against oxidative stress by Linschooten, Joost O., Laubenthal, Julian, Cemeli, Eduardo, Baumgartner, Adolf, Anderson, Diana, Sipinen, Ville E., Brunborg, Gunnar, Haenen, Guido R.M.M., Fthenou, Eleni, Briedé, Jacob J., van Schooten, Frederik J., Godschalk, Roger W.L.

“…Although DNA damage in human spermatozoa is associated with adverse health effects, its origin is not fully understood. Therefore, we assessed biomarkers in…”
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Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding by Hoeks, Joris, Briedé, Jacob J., de Vogel, Johan, Schaart, Gert, Nabben, Miranda, Moonen-Kornips, Esther, Hesselink, Matthijs K.C., Schrauwen, Patrick

“…A high intake of dietary fat has been suggested to diminish mitochondrial functioning in skeletal muscle, possibly attributing to muscular fat accumulation…”
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Response to cytochrome P450-derived versus mitochondrial oxidant stress in acetaminophen hepatotoxicity by Jiang, Jian, Briedé, Jacob J., Jennen, Danyel G.J., Kleinjans, Jos C.S., de Kok, Theo M.C.M.

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The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles by Park, Margriet V.D.Z, Neigh, Arianne M, Vermeulen, Jolanda P, de la Fonteyne, Liset J.J, Verharen, Henny W, Briedé, Jacob J, van Loveren, Henk, de Jong, Wim H

“…Abstract Silver nanoparticles are of interest to be used as antimicrobial agents in wound dressings and coatings in medical devices, but potential adverse…”
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