Search Results - "Bridson, K"

Autotaxin structure–activity relationships revealed through lysophosphatidylcholine analogs by North, E. Jeffrey, Osborne, Daniel A., Bridson, Peter K., Baker, Daniel L., Parrill, Abby L.

“…Lysophosphatidylcholine analogs were synthesized and evaluated for autotaxin substrate recognition. The boxed functional groups were modified to investigate…”
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Laparoscopy in third-world countries by Orr, K Bridson

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Inactivation of aldophosphamide by human aldehyde dehydrogenase isozyme 3 by Giorgianni, Francesco, Bridson, Peter K., Sorrentino, Brian P., Pohl, Jörg, Blakley, Raymond L.

“…Tumors resistant to chemotherapeutic oxazaphosphorines such as cyclophosphamide often overexpress aldehyde dehydrogenase (ALDH), some isozymes of which…”
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Microsomal reduction of 3-amino-1,2,4-benzotriazine 1,4-dioxide to a free radical by Lloyd, R V, Duling, D R, Rumyantseva, G V, Mason, R P, Bridson, P K

“…The drug SR 4233 (3-amino-1,2,4-benzotriazine 1,4-dioxide) is under pharmacological study as the lead compound in a new series of hypoxia-activated drugs, the…”
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Laparoscopic cholecystectomy: what national benefits have been achieved and at what cost? by Bridson Orr, K

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Synthesis of deoxyazepinomycin by BRIDSON, P. K

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FC139 New treatment for molluscum contagiosum in patients with HIV infection by Chard, S.C., Worlidge, P.J., Holder, M.A., Bridson, K., Barton, S.E.

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Imidazodiazepinediones: a new class of adenosine receptor antagonists by Daly, John W, Hide, Izumi, Bridson, Peter K

“…A series of imidazo[4,5-e][1-4]diazepine-5,8-diones were synthesized from hypoxanthines. Certain of these cyclic homologues of caffeine, theophylline,…”
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Efficient Metal-Ion Catalyzed Template-Directed Oligonucleotide Synthesis by Lohrmann, R., Bridson, P. K., Orgel, L. E.

“…The Pb$^{2+}$ and Zn$^{2+}$ ions are efficient catalysts for the polycytidylic acid-directed polymerization of an activated guanylic acid derivative, guanosine…”
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Alkylation of 5-Cyanoimidazole-4-carboxamide by K. Bridson, Peter, V. Iyengar, Rekha

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Intramolecular cyclization of ethyl ω-(5-amino-4-aminocarbonylimidazol-1-yl)carboxylates by Bridson, P. K., McGowan, A., Wilson, C. M., Yeh, Y. M.

“…Attempted elaboration of the title compounds to purines by reaction with ethyl formate leads instead to some novel fused imidazoles by intramolecular…”
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Condensation of activated diguanylates on a poly(C) template by Lohrmann, R, Bridson, P K, Orgel, L E

“…We have studied the metal-ion catalysis of a number of reactions of the isomers of ImpGpG on a poly(C) template. In the absence of a catalytic metal ion,…”
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Synthesis and adenosine receptor affinity of 7-beta-D-ribofuranosylxanthine by Bridson, P K, Lin, X, Melman, N, Ji, X D, Jacobson, K A

“…7-beta-D-Ribofuranosylxanthine, a previously unreported isomer of xanthosine, was prepared in four steps from 7-benzylxanthine. The procedure, which involves…”
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The reaction of 5-aminoimidazole-4-carbohydrazides with orthoesters by Bridson, P. K., Davis, R. A., Renner, L. S.

“…The reaction of 5‐aminoimidazole‐4‐carbohydrazides with orthoesters is shown to yield 1‐amino‐9‐alkyl‐hypoxanthines. Similar reaction of anthranilic acid…”
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The dead do tell tales by Reid, D B

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Snakes and ladders: getting patients into metropolitan public hospitals by Orr, K B

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Catalysis of accurate poly(C)-directed synthesis of 3'-5'-linked oligoguanylates by Zn2 by Bridson, P K, Orgel, L E

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Impact of dressing materials on central venous catheter infection rates by Treston-Aurand, J, Olmsted, R N, Allen-Bridson, K, Craig, C P

“…Transparent, semipermeable, polyurethane dressings have become widely accepted for dressing central venous catheter (CVC) insertion sites. However, there have…”
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Cyclic homologs of xanthines. I. Imidazo[4,5-e][1,4]diazepine-5,8-diones by Bridson, Peter K., Weirich, Timothy P.

“…A useful synthetic approach to variously alkylated 4,5,7,8‐tetrahydro‐6.H‐imidazo[4,5‐e][1,4]diazepine‐5,8‐diones is reported. These compounds are potentially…”
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Cyclic homologs of xanthines. I: Imidazo[4,5-e][1,4]diazepines-5,8-diones by BRIDSON, P. K, WEIRICH, T. P

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