Search Results - "Bridgewater, Laura C."

Gender-based differences in host behavior and gut microbiota composition in response to high fat diet and stress in a mouse model by Bridgewater, Laura C., Zhang, Chenhong, Wu, Yanqiu, Hu, Weiwei, Zhang, Qianpeng, Wang, Jing, Li, Shengtian, Zhao, Liping

“…Obesity is associated with a high prevalence of mood disorders such as anxiety and depression. Both stress and high fat diet can alter the gut microbiota and…”
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The bamboo-eating giant panda harbors a carnivore-like gut microbiota, with excessive seasonal variations by Xue, Zhengsheng, Zhang, Wenping, Wang, Linghua, Hou, Rong, Zhang, Menghui, Fei, Lisong, Zhang, Xiaojun, Huang, He, Bridgewater, Laura C, Jiang, Yi, Jiang, Chenglin, Zhao, Liping, Pang, Xiaoyan, Zhang, Zhihe

“…The giant panda evolved from omnivorous bears. It lives on a bamboo-dominated diet at present, but it still retains a typical carnivorous digestive system and…”
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Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children by Zhang, Chenhong, Yin, Aihua, Li, Hongde, Wang, Ruirui, Wu, Guojun, Shen, Jian, Zhang, Menghui, Wang, Linghua, Hou, Yaping, Ouyang, Haimei, Zhang, Yan, Zheng, Yinan, Wang, Jicheng, Lv, Xiaofei, Wang, Yulan, Zhang, Feng, Zeng, Benhua, Li, Wenxia, Yan, Feiyan, Zhao, Yufeng, Pang, Xiaoyan, Zhang, Xiaojun, Fu, Huaqing, Chen, Feng, Zhao, Naisi, Hamaker, Bruce R., Bridgewater, Laura C., Weinkove, David, Clement, Karine, Dore, Joel, Holmes, Elaine, Xiao, Huasheng, Zhao, Guoping, Yang, Shengli, Bork, Peer, Nicholson, Jeremy K., Wei, Hong, Tang, Huiru, Zhang, Xiaozhuang, Zhao, Liping

“…Gut microbiota has been implicated as a pivotal contributing factor in diet-related obesity; however, its role in development of disease phenotypes in human…”
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Personal microbiome analysis improves student engagement and interest in Immunology, Molecular Biology, and Genomics undergraduate courses by Weber, K Scott, Bridgewater, Laura C, Jensen, Jamie L, Breakwell, Donald P, Nielsen, Brent L, Johnson, Steven M

“…A critical area of emphasis for science educators is the identification of effective means of teaching and engaging undergraduate students. Personal microbiome…”
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Per-Arnt-Sim Kinase (PASK) Deficiency Increases Cellular Respiration on a Standard Diet and Decreases Liver Triglyceride Accumulation on a Western High-Fat High-Sugar Diet by Pape, Jenny A, Newey, Colleen R, Burrell, Haley R, Workman, Audrey, Perry, Katelyn, Bikman, Benjamin T, Bridgewater, Laura C, Grose, Julianne H

“…Diabetes and the related disease metabolic syndrome are epidemic in the United States, in part due to a shift in diet and decrease in physical exercise. PAS…”
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Gut Microbiota Regulates the Interaction between Diet and Genetics to Influence Glucose Tolerance by Franson, Jeralyn J, Grose, Julianne H, Larson, Kaitlyn W, Bridgewater, Laura C

“…Metabolic phenotypes are the result of an intricate interplay between multiple factors, including diet, genotype, and the gut microbiome. Per-Arnt-Sim (PAS)…”
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Biomechanical analysis of the camelid cervical intervertebral disc by Stolworthy, Dean K., Fullwood, R. Amy, Merrell, Tyler M., Bridgewater, Laura C., Bowden, Anton E.

“…Chronic low back pain (LBP) is a prevalent global problem, which is often correlated with degenerative disc disease. The development and use of good, relevant…”
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A Novel Bone Morphogenetic Protein 2 Mutant Mouse, , Displays Impaired Intracellular Handling in Skeletal Muscle by Bridgewater, Laura C., Mayo, Jaime L., Evanson, Bradley G., Whitt, Megan E., Dean, Spencer A., Yates, Joshua D., Holden, Devin N., Schmidt, Alina D., Fox, Christopher L., Dhunghel, Saroj, Steed, Kevin S., Adam, Michael M., Nichols, Caitlin A., Loganathan, Sampath K., Barrow, Jeffery R., Hancock, Chad R.

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Functional Validation of a Complex Loading Whole Spinal Segment Bioreactor Design by Beatty, Amanda M, Bowden, Anton E, Bridgewater, Laura C

“…Intervertebral disk (IVD) degeneration is a prevalent health problem that is highly linked to back pain. To understand the disease and tissue response to…”
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MRI evaluation of spontaneous intervertebral disc degeneration in the alpaca cervical spine by Stolworthy, Dean K., Bowden, Anton E., Roeder, Beverly L., Robinson, Todd F., Holland, Jacob G., Christensen, S. Loyd, Beatty, Amanda M., Bridgewater, Laura C., Eggett, Dennis L., Wendel, John D., Stieger-Vanegas, Susanne M., Taylor, Meredith D.

“…ABSTRACT Animal models have historically provided an appropriate benchmark for understanding human pathology, treatment, and healing, but few animals are known…”
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The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response by Tellez Freitas, Claudia M., Burrell, Haley R., Valdoz, Jonard C., Hamblin, Garrett J., Raymond, Carlee M., Cox, Tyler D., Johnson, Deborah K., Andersen, Joshua L., Weber, K. Scott, Bridgewater, Laura C.

“…We previously identified a nuclear variant of bone morphogenetic protein 2 (BMP2), named nBMP2, that is translated from an alternative start codon. Decreased…”
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Col9a1 enhancer element activated by two interdependent SOX9 dimers by Genzer, Mary Ann, Bridgewater, Laura C

“…The transcription factor SOX9 plays a critical role in chondrogenesis as well as in sex determination. Previous work has suggested that SOX9 functions as a…”
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The BMP2 nuclear variant, nBMP2, is expressed in mouse hippocampus and impacts memory by Cordner, Ryan D., Friend, Lindsey N., Mayo, Jaime L., Badgley, Corinne, Wallmann, Andrew, Stallings, Conrad N., Young, Peter L., Miles, Darla R., Edwards, Jeffrey G., Bridgewater, Laura C.

“…The novel nuclear protein nBMP2 is synthesized from the BMP2 gene by translational initiation at an alternative start codon. We generated a targeted mutant…”
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A novel retinoic acid-response element requires an enhancer element mediator for transcriptional activation by Harris, Laura R, Kamarainen, Olli-Pekka, Sevakivi, Minna, Miller, Gwen C, Clarke, James W, Potter, Jennifer L, Bridgewater, Laura C

“…The Col11a2 gene codes for alpha2(XI), a subunit of type XI collagen that is a critical component of the cartilage extracellular matrix. The 5' regulatory…”
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SOX9 mediates the retinoic acid-induced HES-1 gene expression in human breast cancer cells by Müller, Patrick, Crofts, Justin D, Newman, Ben S, Bridgewater, Laura C, Lin, Chin-Yo, Gustafsson, Jan-Åke, Ström, Anders

“…We have previously shown that the anti-proliferative effect of retinoic acid in human breast cancer cell line MCF-7 is dependent on HES-1 expression. Here we…”
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The transcription factor Lc-Maf participates in Col27a1 regulation during chondrocyte maturation by Mayo, Jaime L., Holden, Devin N., Barrow, Jeffery R., Bridgewater, Laura C.

“…The transcription factor Lc-Maf, which is a splice variant of c-Maf, is expressed in cartilage undergoing endochondral ossification and participates in the…”
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Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model by Bridgewater, Laura C., Weber, K. Scott, Reynolds, Paul R., Merriam, Kayla R., Christensen, S. Loyd, Bailey, K. Tyson, Nichols, Brandt A., Goar, Wesley A., Olsen, Daniel S., Wilson, Eric

“…We recently identified a nuclear variant of the BMP2 growth factor, called nBMP2. In an effort to understand the function of this variant protein, we generated…”
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The new collagen gene COL27A1 contains SOX9-responsive enhancer elements by Jenkins, Elizabeth, Moss, Jennie B., Pace, James M., Bridgewater, Laura C.

“…The most recently discovered collagen gene, COL27A1, codes for type XXVII collagen. The COL27A1 gene is strongly expressed in developing cartilage and weakly…”
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A novel bone morphogenetic protein 2 mutant mouse, nBmp2NLS(tm), displays impaired intracellular Ca2+ handling in skeletal muscle by Bridgewater, Laura C, Mayo, Jaime L, Evanson, Bradley G, Whitt, Megan E, Dean, Spencer A, Yates, Joshua D, Holden, Devin N, Schmidt, Alina D, Fox, Christopher L, Dhunghel, Saroj, Steed, Kevin S, Adam, Michael M, Nichols, Caitlin A, Loganathan, Sampath K, Barrow, Jeffery R, Hancock, Chad R

“…We recently reported a novel form of BMP2, designated nBMP2, which is translated from an alternative downstream start codon and is localized to the nucleus…”
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The transcription factor Sox9 is degraded by the ubiquitin–proteasome system and stabilized by a mutation in a ubiquitin-target site by Akiyama, Haruhiko, Kamitani, Tetsu, Yang, Xiaohong, Kandyil, Roshini, Bridgewater, Laura C., Fellous, Marc, Mori-Akiyama, Yuko, de Crombrugghe, Benoit

“…Sox9 is a transcription factor that is critical for chondrogenesis, testis determination, and development of several other organs in vertebrates. Thus the…”
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