Search Results - "Bridges, P"

Delivery Approaches for Therapeutic Genome Editing and Challenges by Ates, Ilayda, Rathbone, Tanner, Stuart, Callie, Bridges, P Hudson, Cottle, Renee N

“…Impressive therapeutic advances have been possible through the advent of zinc-finger nucleases and transcription activator-like effector nucleases. However,…”
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Guidelines for Artificial Intelligence in Medicine: Literature Review and Content Analysis of Frameworks by Crossnohere, Norah L, Elsaid, Mohamed, Paskett, Jonathan, Bose-Brill, Seuli, Bridges, John F P

“…Background Artificial intelligence (AI) is rapidly expanding in medicine despite a lack of consensus on its application and evaluation. Objective We sought to…”
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Using CubeSat/micro-satellite technology to demonstrate the Autonomous Assembly of a Reconfigurable Space Telescope (AAReST) by Underwood, Craig, Pellegrino, Sergio, Lappas, Vaios J., Bridges, Christopher P., Baker, John

“…Future space telescopes with diameter over 20m will require new approaches: either high-precision formation flying or in-orbit assembly. We believe the latter…”
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Identification and Characterization of a G Protein-binding Cluster in α7 Nicotinic Acetylcholine Receptors by King, Justin R., Nordman, Jacob C., Bridges, Samuel P., Lin, Ming-Kuan, Kabbani, Nadine

“…α7 nicotinic acetylcholine receptors (nAChRs) play an important role in synaptic transmission and inflammation. In response to ligands, this receptor channel…”
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Older Adults' Views and Communication Preferences About Cancer Screening Cessation by Schoenborn, Nancy L, Lee, Kimberley, Pollack, Craig E, Armacost, Karen, Dy, Sydney M, Bridges, John F P, Xue, Qian-Li, Wolff, Antonio C, Boyd, Cynthia

“…Older adults with limited life expectancy are frequently screened for cancer even though it exposes them to risks of screening with minimal benefit. Patient…”
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A transcriptomal analysis of bovine oviductal epithelial cells collected during the follicular phase versus the luteal phase of the estrous cycle by Cerny, K L, Garrett, E, Walton, A J, Anderson, L H, Bridges, P J

“…Reproductive success depends on a functional oviduct for gamete storage, maturation, fertilization, and early embryonic development. The ovarian-derived…”
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Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development by Du, Yina, Kitzmiller, Joseph A, Sridharan, Anusha, Perl, Anne K, Bridges, James P, Misra, Ravi S, Pryhuber, Gloria S, Mariani, Thomas J, Bhattacharya, Soumyaroop, Guo, Minzhe, Potter, S Steven, Dexheimer, Phillip, Aronow, Bruce, Jobe, Alan H, Whitsett, Jeffrey A, Xu, Yan

“…'LungGENS', our previously developed web tool for mapping single-cell gene expression in the developing lung, has been well received by the pulmonary research…”
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Alveolar epithelial progenitor cells require Nkx2-1 to maintain progenitor-specific epigenomic state during lung homeostasis and regeneration by Toth, Andrea, Kannan, Paranthaman, Snowball, John, Kofron, Matthew, Wayman, Joseph A., Bridges, James P., Miraldi, Emily R., Swarr, Daniel, Zacharias, William J.

“…Lung epithelial regeneration after acute injury requires coordination cellular coordination to pattern the morphologically complex alveolar gas exchange…”
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A best–worst scaling experiment to prioritize concern about ethical issues in citizen science reveals heterogeneity on people-level v. data-level issues by Guerrini, Christi J., Crossnohere, Norah L., Rasmussen, Lisa, Bridges, John F. P.

“…“Citizen science” refers to the participation of lay individuals in scientific studies and other activities having scientific objectives. Citizen science gives…”
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Using best-worst scaling to inform policy decisions in Africa: a literature review by Beres, Laura K, Campoamor, Nicola B, Hawthorn, Rachael, Mugambi, Melissa L, Mulabe, Musunge, Vhlakis, Natlie, Kabongo, Michael, Schuster, Anne, Bridges, John F P

“…Stakeholder engagement in policy decision-making is critical to inform required trade-offs, especially in low-and-middle income settings, such as many African…”
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Prioritization of ethical concerns regarding HIV molecular epidemiology by public health practitioners and researchers by Schuster, Anne L R, Bollinger, Juli, Geller, Gail, Little, Susan J, Mehta, Sanjay R, Sanchez, Travis, Sugarman, Jeremy, Bridges, John F P

“…HIV molecular epidemiology (HIV ME) can support the early detection of emerging clusters of new HIV infections by combining HIV sequence data routinely…”
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Adaptive mesh refinement in the fast lane by Dunning, D., Marts, W., Robey, R.W., Bridges, P.

“…•Increased composability through a separation of concerns for physicists and computational scientists.•Streamlining the pathway when converting regular grid…”
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Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis by McCarthy, Cormac, Lee, Elinor, Bridges, James P., Sallese, Anthony, Suzuki, Takuji, Woods, Jason C., Bartholmai, Brian J., Wang, Tisha, Chalk, Claudia, Carey, Brenna C., Arumugam, Paritha, Shima, Kenjiro, Tarling, Elizabeth J., Trapnell, Bruce C.

“…Pulmonary alveolar proteinosis (PAP) is a syndrome of reduced GM-CSF-dependent, macrophage-mediated surfactant clearance, dysfunctional foamy alveolar…”
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Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis by Lee, Elinor, Williams, Kevin J., McCarthy, Cormac, Bridges, James P., Redente, Elizabeth F., de Aguiar Vallim, Thomas Q., Barrington, Robert A., Wang, Tisha, Tarling, Elizabeth J.

“…Pulmonary alveolar proteinosis (PAP) is a life-threatening, rare lung syndrome for which there is no cure and no approved therapies. PAP is a disease of lipid…”
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Neoadjuvant Therapy for Resectable and Borderline Resectable Pancreatic Cancer: A Meta-Analysis of Randomized Controlled Trials by Cloyd, Jordan M, Heh, Victor, Pawlik, Timothy M, Ejaz, Aslam, Dillhoff, Mary, Tsung, Allan, Williams, Terence, Abushahin, Laith, Bridges, John F P, Santry, Heena

“…The efficacy of neoadjuvant therapy (NT) versus surgery first (SF) for pancreatic ductal adenocarcinoma (PDAC) remains controversial. A random-effects…”
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The impact of metabolic syndrome severity on racial and ethnic disparities in Metabolic Dysfunction-Associated Steatotic Liver Disease by Elsaid, Mohamed I, Bridges, John F P, Mumtaz, Khalid, Li, Na, Sobotka, Lindsay, Rustgi, Vinod K, Paskett, Electra D

“…Previous studies have examined the effects of metabolic syndrome (MetS) rather than its severity on race and ethnic disparities in Metabolic…”
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A Review of Transsplenic Access for Portal Vein Interventions by Gayed, Antony, Bridges, P. Hudson, Johnson, D. Thor

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Barriers to diverse clinical trial participation in Duchenne muscular dystrophy: Engaging Hispanic/Latina caregivers and health professionals by Crossnohere, Norah L, Campoamor, Nicola B, Camino, Eric, Dresnick, Erin, Martschenko, Daphne Oluwaseun, Rodrigues, Viana, Apkon, Susan, Hazlett, Alexis, Mittur, Dhruv, Rodriguez, Priscilla E, Bridges, John F P, Armstrong, Niki

“…Despite the increasing availability of clinical trials in Duchenne muscular dystrophy, racial/ethnic minorities and other populations facing health disparities…”
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Infection‐induced endothelial amyloids impair memory by Balczon, Ron, Pittet, Jean‐Francois, Wagener, Brant M., Moser, Stephen A., Voth, Sarah, Vorhees, Charles V., Williams, Michael T., Bridges, James P., Alvarez, Diego F., Koloteva, Anna, Xu, Yuanyuan, Zha, Xiang‐Ming, Audia, Jonathon P., Stevens, Troy, Lin, Mike T.

“…ABSTRACTPatients with nosocomial pneumonia exhibit elevated levels of neurotoxic amyloid and tau proteins in the cerebrospinal fluid (CSF). In vitro studies…”
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Analysis of Patient Preferences in Lung Cancer - Estimating Acceptable Tradeoffs Between Treatment Benefit and Side Effects by Janssen, Ellen M, Dy, Sydney M, Meara, Alexa S, Kneuertz, Peter J, Presley, Carolyn J, Bridges, John F P

“…Increased treatment options and longer survival for lung cancer have generated increased interest in patient preferences. Previous studies of patient…”
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