Serologic responses to eastern and western equine encephalomyelitis vaccination in previously vaccinated horses

A prospective study was performed to determine the serologic response of previously vaccinated horses to revaccination against eastern and western equine encephalomyelitis (EEE and WEE). Horses responded variably to each antigen, and some horses had low or undetectable antibodies 6 months after vacc...

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Bibliographic Details
Published in:	Veterinary therapeutics Vol. 4; no. 3; p. 242
Main Authors:	Waldridge, Bryan M, Wenzel, James G W, Ellis, A C, Rowe-Morton, Sarah E, Bridges, E Ricardo, D'Andrea, George, Wint, Rennia
Format:	Journal Article
Language:	English
Published:	United States 2003
Subjects:	Animals Antibodies, Viral - blood Encephalitis Virus, Eastern Equine - immunology Encephalitis Virus, Western Equine - immunology Encephalomyelitis, Eastern Equine - immunology Encephalomyelitis, Eastern Equine - veterinary Encephalomyelitis, Western Equine - immunology Encephalomyelitis, Western Equine - veterinary Female Horse Diseases - immunology Horses Prospective Studies Viral Vaccines - immunology
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Summary:	A prospective study was performed to determine the serologic response of previously vaccinated horses to revaccination against eastern and western equine encephalomyelitis (EEE and WEE). Horses responded variably to each antigen, and some horses had low or undetectable antibodies 6 months after vaccination. Some horses did not develop increasing titers to EEE or WEE despite recent vaccination. Geometric mean titers peaked 2 weeks after revaccination and were significantly increased from before revaccination. Except for one horse, EEE:WEE titer ratios ranged from 0.25 to 2.0. Regular vaccination against EEE and WEE did not interfere with testing for Saint Louis encephalitis.
ISSN:	1528-3593