Search Results - "Bridges, Bryn A"

Evidence relevant to untargeted and transgenerational effects in the offspring of irradiated parents by Little, Mark P., Goodhead, Dudley T., Bridges, Bryn A., Bouffler, Simon D.

“…In this article we review health effects in offspring of human populations exposed as a result of radiotherapy and some groups exposed to chemotherapy. We also…”
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Radiation and mutation—Some personal reflections on the early days by Bridges, Bryn A.

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Error-prone DNA repair and translesion dna synthesis II : The inducible SOS hypothesis by BRIDGES, Bryn A

“…Evelyn Witkin hypothesized in 1967 that bacterial cell division is controlled by a repressor which, like the lambda repressor, is inactivated by a complex…”
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Effectiveness of tritium beta particles by Bridges, Bryn A

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RBE-LET relationships in mutagenesis by ionizing radiation by Nikjoo, H, Munson, R J, Bridges, B A

“…The paper considers the relationship between the quality of radiation and biological lesions produced by ionizing radiation. The paper provides a brief review…”
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Error-prone DNA repair and translesion synthesis: Focus on the replication fork by Bridges, Bryn A.

“…Dean Rupp and Paul Howard-Flanders showed that, following exposure to ultraviolet light, bacteria deficient in nucleotide excision repair synthesised DNA with…”
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Hypermutation in bacteria and other cellular systems by Bridges, Bryn A., Bridges, Bryn A.

“…A temporary state of hypermutation can in principle arise through an increase in the rate of polymerase errors (which may or may not be triggered by template…”
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Error-prone repair and translesion synthesis III: The activation of UmuD (or less is more) by Bridges, Bryn A.

“…Following DNA damage to Escherichia coli bacteria, RecA protein is activated by binding to single stranded DNA and cleaves its own gene repressor (LexA…”
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Strange goings-on in the mouse germ line by Bridges, Bryn A.

“…It is a conventional paradigm that mutagens lead to changes in nucleotide sequence when the cell attempts to repair or replicate lesions in DNA (such as…”
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Radiation and Germline Mutation at Repeat Sequences: Are We in the Middle of a Paradigm Shift? by Bridges, Bryn A.

“…Bridges, B. A. Radiation and Germline Mutation at Repeat Sequences: Are We in the Middle of a Paradigm Shift? Radiat. Res. 156, 631–641 (2001). Two assumptions…”
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Unfinished business: an essay on finally leaving the bench by Bridges, Bryn A

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DNA turnover and mutation in resting cells by Bridges, B A

“…There is growing evidence that mutations can arise in non-dividing cells (both bacterial and mammalian) in the absence of chromosomal replication. The…”
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Dirty Transcripts from Clean DNA by Bridges, Bryn A.

“…The results of research and study conducted on DNA templates are provided. The focus is on RNA transcription and the forces which cease them from functioning…”
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mutY 'directs' mutation? by Bridges, Bryn A

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Elevated mutation rate in mutT bacteria during starvation: evidence for DNA turnover? by Bridges, B A

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Reflections on the 8th International Conference on Environmental Mutagens by Bridges, Bryn A., Friedberg, Errol C.

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DNA repair: Getting past a lesion – at a cost by Bridges, Bryn A

“…Bacteria survive many types of synthesis-blocking DNA lesion by inducing a number of proteins that enable their polymerases to synthesize past a lesion, albeit…”
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DNA synthesis and viability of a mutT derivative of Escherichia coli WP2 under conditions of amino acid starvation and relation to stationary-phase (adaptive) mutation by Bridges, B A, Ereira, S

“…Escherichia coli WP2 bacteria with an ochre amino acid auxotrophy show no evidence of growth during the first few days after plating at densities above 10(8)…”
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Effect of endogenous carotenoids on "adaptive" mutation in Escherichia coli FC40 by Bridges, B A, Foster, P L, Timms, A R

“…The appearance over many days of Lac(+) frameshift mutations in Escherichia coli strain FC40 incubated on lactose selection plates is a classic example of…”
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Are there DNA damage checkpoints in E. coli? by Bridges, B A

“…The concept of regulatory 'checkpoints' in the eukaryotic cycle has proved to be a fruitful one. Here, its applicability to the bacterial cell cycle is…”
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