Search Results - "Bride, Karen L."

Sirolimus is effective in relapsed/refractory autoimmune cytopenias: results of a prospective multi-institutional trial by Bride, Karen L., Vincent, Tiffaney, Smith-Whitley, Kim, Lambert, Michele P., Bleesing, Jack J., Seif, Alix E., Manno, Catherine S., Casper, James, Grupp, Stephan A., Teachey, David T.

“…Patients with autoimmune multilineage cytopenias are often refractory to standard therapies requiring chronic immunosuppression with medications with limited…”
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Rational drug combinations with CDK4/6 inhibitors in acute lymphoblastic Leukemia by Bride, Karen L, Hu, Hai, Tikhonova, Anastasia, Fuller, Tori J, Vincent, Tiffaney L, Shraim, Rawan, Li, Marilyn M, Carroll, William L, Raetz, Elizabeth A, Aifantis, Iannis, Teachey, David T

“…Despite improvements in outcomes for children with B and T-cell acute lymphoblastic leukemia (B-ALL and T-ALL), patients with resistant or relapsed disease…”
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Utility of the immature platelet fraction in pediatric immune thrombocytopenia: Differentiating from bone marrow failure and predicting bleeding risk by McDonnell, Alicia, Bride, Karen L., Lim, Derick, Paessler, Michele, Witmer, Char M., Lambert, Michele P.

“…Background Differentiating childhood immune thrombocytopenia (ITP) from other cause of thrombocytopenia remains a diagnosis of exclusion. Additionally factors…”
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Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation by Mande, Purvi, Zirak, Bahar, Ko, Wei-Che, Taravati, Keyon, Bride, Karen L, Brodeur, Tia Y, Deng, April, Dresser, Karen, Jiang, Zhaozhao, Ettinger, Rachel, Fitzgerald, Katherine A, Rosenblum, Michael D, Harris, John E, Marshak-Rothstein, Ann

“…Toll-like receptors TLR7 and TLR9 are both implicated in the activation of autoreactive B cells and other cell types associated with systemic lupus…”
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Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia by Bride, Karen L., Vincent, Tiffaney L., Im, Soo-Yeon, Aplenc, Richard, Barrett, David M., Carroll, William L., Carson, Robin, Dai, Yunfeng, Devidas, Meenakshi, Dunsmore, Kimberly P., Fuller, Tori, Glisovic-Aplenc, Tina, Horton, Terzah M., Hunger, Stephen P., Loh, Mignon L., Maude, Shannon L., Raetz, Elizabeth A., Winter, Stuart S., Grupp, Stephan A., Hermiston, Michelle L., Wood, Brent L., Teachey, David T.

“…As a consequence of acquired or intrinsic disease resistance, the prognosis for patients with relapsed or refractory T-cell acute lymphoblastic leukemia…”
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Catheter-directed Thrombolysis for Neonatal IVC and Bilateral Renal Vein Thrombosis: A Case Report by Guichet, Phillip L., Jasinski, Sylwia, Malaga-Dieguez, Laura, De Los Reyes, Francis A., Ahuja, Tania, Bride, Karen L., Patel, Amish

“…Renal vein thrombosis is the most common non–catheter-associated venous thromboembolism event in neonates, accounting for up to 20% of cases. Although…”
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Hematopoietic Stem Cell Transplantation (HSCT) for Acute Lymphoblastic Leukemia (ALL) in First Remission (CR1): A Single-Institution Retrospective Cohort Study Demonstrating Excellent Event-Free (EFS) and Overall Survival (OS) by Bride, Karen L., MD, PhD, Freedman, Jason L., MD, MSCE, Bunin, Nancy J., MD, Hunger, Stephen P., MD, Rheingold, Susan R., MD, Seif, Alix E., MD, MPH

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Evaluation of Phenotype-Genotype Correlation in Two Common PIEZO1 Mutations p.R2456H and p.L2495_E2495dup by Risinger, Mary, Black, Vandy, Hsieh, Loan, Prins, Renee C., Menell, Jill, Badawi, Mohamad, Rutherford, Cynthia, Bride, Karen L., Niss, Omar, Quinn, Charles T., Giger Seu, Katie, Zhang, Wenying, Kalfa, Theodosia A.

“…Hereditary xerocytosis (HX) is a rare autosomal dominant hemolytic anemia caused by mutations in the mechanosensitive cation channel PIEZO1 or, less commonly,…”
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Targetting CD38 in T Cell Acute Lymphoblastic Leukemia by Bride, Karen L., Vincent, Tiffaney L., Im, Soo-Yeon, Barrett, David M., Hermiston, Michelle L., Horton, Terzah M., Loh, Mignon L., Maude, Shannon L, Grupp, Stephan A, Wood, Brent, Teachey, David T

“…Targeted immunotherapy has become a promising emerging therapeutic strategy for many cancers. No safe and effective immunotherapies have been developed for…”
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