Search Results - "Bricola, Rafael"
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Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPRmt in the hypothalamus of mice
Published in Scientific reports (15-02-2021)“…The maintenance of mitochondrial activity in hypothalamic neurons is determinant to the control of energy homeostasis in mammals. Disturbs in the mitochondrial…”
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Aerobic Exercise Training Induces the Mitonuclear Imbalance and UPRmt in the Skeletal Muscle of Aged Mice
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-12-2020)“…Abstract The impairment of the mitochondrial functions is a hallmark of aging. During aging, there is a downregulation of two mechanisms strictly associated…”
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Evidence for a neuromuscular circuit involving hypothalamic interleukin-6 in the control of skeletal muscle metabolism
Published in Science advances (29-07-2022)“…Hypothalamic interleukin-6 (IL6) exerts a broad metabolic control. Here, we demonstrated that IL6 activates the ERK1/2 pathway in the ventromedial hypothalamus…”
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High-intensity exercise training induces mitonuclear imbalance and activates the mitochondrial unfolded protein response in the skeletal muscle of aged mice
Published in GeroScience (01-06-2021)“…The impairment of mitochondrial metabolism is a hallmark of aging. Mitonuclear imbalance and the mitochondrial unfolded protein response (UPRmt) are two…”
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Aging reduces ABHD5 protein content in the adipose tissue of mice: The reversal effect of exercise
Published in Cell biochemistry and function (01-01-2023)“…Dysfunction of the adipose tissue metabolism is considered as a significant hallmark of aging. It has been proposed that α‐β hydrolase domain containing 5…”
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Acute exercise modulates Trim63 and Bmal1 in the skeletal muscle of IL-10 knockout mice
Published in Cytokine (Philadelphia, Pa.) (01-03-2024)“…The anti-inflammatory role of physical exercise is mediated by interleukin 10 (IL-10), and their release is possibly upregulated in response to IL-6. Previous…”
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7
Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPR mt in the hypothalamus of mice
Published in Scientific reports (15-02-2021)“…The maintenance of mitochondrial activity in hypothalamic neurons is determinant to the control of energy homeostasis in mammals. Disturbs in the mitochondrial…”
Get full text
Journal Article