Search Results - "Briceno, Stephanie W"

Discovery of the CCR1 Antagonist, BMS-817399, for the Treatment of Rheumatoid Arthritis by Santella, Joseph B, Gardner, Daniel S, Duncia, John V, Wu, Hong, Dhar, Murali, Cavallaro, Cullen, Tebben, Andrew J, Carter, Percy H, Barrish, Joel C, Yarde, Melissa, Briceno, Stephanie W, Cvijic, Mary Ellen, Grafstrom, R. Robert, Liu, Richard, Patel, Sima R, Watson, Andrew J, Yang, Guchen, Rose, Anne V, Vickery, Rodney D, Caceres-Cortes, Janet, Caporuscio, Christian, Camac, Daniel M, Khan, Javed A, An, Yongmi, Foster, William R, Davies, Paul, Hynes, John

“…High-affinity, functionally potent, urea-based antagonists of CCR1 have been discovered. Modulation of PXR transactivation has revealed the selective and…”
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The discovery of BMS-457, a potent and selective CCR1 antagonist by Gardner, Daniel S., Santella, Joseph B., Duncia, John V., Carter, Percy H., Dhar, T.G.Murali, Wu, Hong, Guo, Weiwei, Cavallaro, Cullen, Van Kirk, Katy, Yarde, Melissa, Briceno, Stephanie W., Robert Grafstrom, R., Liu, Richard, Patel, Sima R., Tebben, Andrew J., Camac, Dan, Khan, Javed, Watson, Andrew, Yang, Guchen, Rose, Anne, Foster, William R., Cvijic, Mary Ellen, Davies, Paul, Hynes, John

“…A series of compounds which exhibited good human CCR1 binding and functional potency was modified resulting in the discovery of a novel series of high…”
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