Search Results - "Briant, Linford Jb"
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Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes
Published in eLife (17-11-2021)“…Insulin-induced hypoglycemia is a major treatment barrier in type-1 diabetes (T1D). Accordingly, it is important that we understand the mechanisms regulating…”
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2
Innervation modulates the functional connectivity between pancreatic endocrine cells
Published in eLife (04-04-2022)“…The importance of pancreatic endocrine cell activity modulation by autonomic innervation has been debated. To investigate this question, we established an in…”
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GC-Globulin/Vitamin D-Binding Protein Is Required for Pancreatic α-Cell Adaptation to Metabolic Stress
Published in Diabetes (New York, N.Y.) (01-02-2023)“…GC-globulin (GC), or vitamin D-binding protein, is a multifunctional protein involved in the transport of circulating vitamin 25(OH)D and fatty acids, as well…”
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Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state
Published in Cell metabolism (01-02-2022)“…In diabetes, glucagon secretion from pancreatic α cells is dysregulated. The underlying mechanisms, and whether dysfunction occurs uniformly among cells,…”
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Mapping the cellular electrophysiology of rat sympathetic preganglionic neurones to their roles in cardiorespiratory reflex integration: a whole cell recording study in situ
Published in The Journal of physiology (15-05-2014)“…Key points Sympathetic preganglionic neurones (SPNs) gatekeep the activity flowing from the CNS to the periphery and their intrinsic properties are believed to…”
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Modelling the vascular response to sympathetic postganglionic nerve activity
Published in Journal of theoretical biology (21-04-2015)“…This paper explores the influence of burst properties of the sympathetic nervous system on arterial contractility. Specifically, a mathematical model is…”
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