Search Results - "Brian Wasik"

Effects of Sialic Acid Modifications on Virus Binding and Infection by Wasik, Brian R, Barnard, Karen N, Parrish, Colin R

“…Sialic acids (Sias) are abundantly displayed on the surfaces of vertebrate cells, and particularly on all mucosal surfaces. Sias interact with microbes of many…”
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Single Particle Analysis of H3N2 Influenza Entry Differentiates the Impact of the Sialic Acids (Neu5Ac and Neu5Gc) on Virus Binding and Membrane Fusion by Chien, Yu-An Annie, Alford, Brynn K, Wasik, Brian R, Weichert, Wendy S, Parrish, Colin R, Daniel, Susan

“…Entry of influenza A viruses (IAVs) into host cells is initiated by binding to sialic acids (Sias), their primary host cell receptor, followed by endocytosis…”
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Onward transmission of viruses: how do viruses emerge to cause epidemics after spillover? by Wasik, Brian R, de Wit, Emmie, Munster, Vincent, Lloyd-Smith, James O, Martinez-Sobrido, Luis, Parrish, Colin R

“…The critical step in the emergence of a new epidemic or pandemic viral pathogen occurs after it infects the initial spillover host and then is successfully…”
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On the Biological Success of Viruses by Wasik, Brian R, Turner, Paul E

“…Are viruses more biologically successful than cellular life? Here we examine many ways of gauging biological success, including numerical abundance,…”
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Canine and Feline Influenza by Wasik, Brian R, Voorhees, Ian E H, Parrish, Colin R

“…Influenza virus infections of carnivores-primarily in dogs and in large and small cats-have been repeatedly observed to be caused by a number of direct…”
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Modified Sialic Acids on Mucus and Erythrocytes Inhibit Influenza A Virus Hemagglutinin and Neuraminidase Functions by Barnard, Karen N, Alford-Lawrence, Brynn K, Buchholz, David W, Wasik, Brian R, LaClair, Justin R, Yu, Hai, Honce, Rebekah, Ruhl, Stefan, Pajic, Petar, Daugherity, Erin K, Chen, Xi, Schultz-Cherry, Stacey L, Aguilar, Hector C, Varki, Ajit, Parrish, Colin R

“…Sialic acids (Sia) are the primary receptors for influenza viruses and are widely displayed on cell surfaces and in secreted mucus. Sia may be present in…”
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Pregnancy enables antibody protection against intracellular infection by Erickson, John J., Archer-Hartmann, Stephanie, Yarawsky, Alexander E., Miller, Jeanette L. C., Seveau, Stephanie, Shao, Tzu-Yu, Severance, Ashley L., Miller-Handley, Hilary, Wu, Yuehong, Pham, Giang, Wasik, Brian R., Parrish, Colin R., Hu, Yueh-Chiang, Lau, Joseph T. Y., Azadi, Parastoo, Herr, Andrew B., Way, Sing Sing

“…Adaptive immune components are thought to exert non-overlapping roles in antimicrobial host defence, with antibodies targeting pathogens in the extracellular…”
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Influenza Viruses in Mice: Deep Sequencing Analysis of Serial Passage and Effects of Sialic Acid Structural Variation by Wasik, Brian R, Voorhees, Ian E H, Barnard, Karen N, Alford-Lawrence, Brynn K, Weichert, Wendy S, Hood, Grace, Nogales, Aitor, Martínez-Sobrido, Luis, Holmes, Edward C, Parrish, Colin R

“…Influenza A viruses have regularly jumped to new host species to cause epidemics or pandemics, an evolutionary process that involves variation in the viral…”
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Reversible O‑Acetyl Migration within the Sialic Acid Side Chain and Its Influence on Protein Recognition by Ji, Yang, Sasmal, Aniruddha, Li, Wanqing, Oh, Lisa, Srivastava, Saurabh, Hargett, Audra A, Wasik, Brian R, Yu, Hai, Diaz, Sandra, Choudhury, Biswa, Parrish, Colin R, Freedberg, Darón I, Wang, Lee-Ping, Varki, Ajit, Chen, Xi

“…O-Acetylation is a common naturally occurring modification of carbohydrates and is especially widespread in sialic acids, a family of nine-carbon acidic…”
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Development and applications of sialoglycan-recognizing probes (SGRPs) with defined specificities: exploring the dynamic mammalian sialoglycome by Srivastava, Saurabh, Verhagen, Andrea, Sasmal, Aniruddha, Wasik, Brian R, Diaz, Sandra, Yu, Hai, Bensing, Barbara A, Khan, Naazneen, Khedri, Zahra, Secrest, Patrick, Sullam, Paul, Varki, Nissi, Chen, Xi, Parrish, Colin R, Varki, Ajit

“…Glycans that are abundantly displayed on vertebrate cell surface and secreted molecules are often capped with terminal sialic acids (Sias). These diverse…”
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Isolation, cloning and analysis of parvovirus-specific canine antibodies from peripheral blood B cells by Früh, Simon P., Adu, Oluwafemi F., López-Astacio, Robert A., Weichert, Wendy S., Wasik, Brian R., Parrish, Colin R.

“…B-cell cloning methods enable the analysis of antibody responses against target antigens and can be used to reveal the host antibody repertoire, antigenic…”
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Expression of 9- O - and 7,9- O -Acetyl Modified Sialic Acid in Cells and Their Effects on Influenza Viruses by Barnard, Karen N, Wasik, Brian R, LaClair, Justin R, Buchholz, David W, Weichert, Wendy S, Alford-Lawrence, Brynn K, Aguilar, Hector C, Parrish, Colin R

“…Sialic acids (Sia) are widely displayed on the surfaces of cells and tissues. Sia come in a variety of chemically modified forms, including those with acetyl…”
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Viral Capsid, Antibody, and Receptor Interactions: Experimental Analysis of the Antibody Escape Evolution of Canine Parvovirus by López-Astacio, Robert A, Adu, Oluwafemi F, Goetschius, Daniel J, Lee, Hyunwook, Weichert, Wendy S, Wasik, Brian R, Frueh, Simon P, Alford, Brynn K, Voorhees, Ian E H, Flint, Joseph F, Saddoris, Sarah, Goodman, Laura B, Holmes, Edward C, Hafenstein, Susan L, Parrish, Colin R

“…Canine parvovirus (CPV) is a small nonenveloped single-stranded DNA virus that causes serious diseases in dogs worldwide. The original strain of the virus…”
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Pre-B acute lymphoblastic leukemia expresses cell surface nucleolin as a 9-O-acetylated sialoglycoprotein by Joo, Eun Ji, Wasik, Brian R, Parrish, Colin, Paz, Helicia, Mϋhlenhoff, Martina, Abdel-Azim, Hisham, Groffen, John, Heisterkamp, Nora

“…Precursor B acute lymphoblastic leukemias (pre-B ALLs) abnormally express a specific glycan structure, 9- O- acetylated sialic acid (9 -O- Ac-Sia), on their…”
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A Chemical Biology Solution to Problems with Studying Biologically Important but Unstable 9‑O-Acetyl Sialic Acids by Khedri, Zahra, Xiao, An, Yu, Hai, Landig, Corinna Susanne, Li, Wanqing, Diaz, Sandra, Wasik, Brian R, Parrish, Colin R, Wang, Lee-Ping, Varki, Ajit, Chen, Xi

“…9-O-Acetylation is a common natural modification on sialic acids (Sias) that terminate many vertebrate glycan chains. This ester group has striking effects on…”
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Sequence dynamics of three influenza A virus strains grown in different MDCK cell lines, including those expressing different sialic acid receptors by Barnard, Karen N., Wasik, Brian R., Alford, Brynn K., Hayward, Jessica J., Weichert, Wendy S., Voorhees, Ian E. H., Holmes, Edward C., Parrish, Colin R.

“…Viruses are often cultured in cell lines for research and vaccine development, and those often differ from the natural hosts or tissues. Cell lines can also…”
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Method comparison of targeted influenza A virus typing and whole-genome sequencing from respiratory specimens of companion animals by Mitchell, Patrick K., Cronk, Brittany D., Voorhees, Ian E. H., Rothenheber, Derek, Anderson, Renee R., Chan, Timothy H., Wasik, Brian R., Dubovi, Edward J., Parrish, Colin R., Goodman, Laura B.

“…Epidemics of H3N8 and H3N2 influenza A viruses (IAVs) in dogs, along with recognition of spillover infections from IAV strains typically found in humans or…”
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STOCHASTIC TEMPERATURES IMPEDE RNA VIRUS ADAPTATION by Alto, Barry W., Wasik, Brian R., Morales, Nadya M., Turner, Paul E.

“…Constant environments are often assumed to favor the evolution of specialization whereas exposure to changing environments may favor the evolution of…”
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Delayed transmission selects for increased survival of vesicular stomatitis virus by Wasik, Brian R., Bhushan, Ambika, Ogbunugafor, C. Brandon, Turner, Paul E.

“…Life-history theory predicts that traits for survival and reproduction cannot be simultaneously maximized in evolving populations. For this reason, in obligate…”
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Distribution of O-Acetylated Sialic Acids among Target Host Tissues for Influenza Virus by Wasik, Brian R, Barnard, Karen N, Ossiboff, Robert J, Khedri, Zahra, Feng, Kurtis H, Yu, Hai, Chen, Xi, Perez, Daniel R, Varki, Ajit, Parrish, Colin R

“…Sialic acids (Sias) are important glycans displayed on the cells and tissues of many different animals and are frequent targets for binding and modification by…”
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