Search Results - "Brian F. C. Clark"
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Science fact and the SENS agenda
Published in EMBO reports (01-11-2005)“…What can we reasonably expect from ageing research?…”
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Mild heat stress stimulates 20S proteasome and its 11S activator in human fibroblasts undergoing aging in vitro
Published in Cell stress & chaperones (01-03-2004)“…Repeated mild heat shock (RMHS) has been shown to have several beneficial hormetic effects on human skin fibroblast undergoing aging in vitro. Because an…”
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The crystal structure of tRNA
Published in Journal of biosciences (01-10-2006)Get full text
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Kinetin—A multiactive molecule
Published in International journal of biological macromolecules (20-02-2007)“…Cytokinins are important adenine derivatives that serve as hormones to control many processes in plants. They were discovered as factors that promote cell…”
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Notes from Abroad on the Deciphering of Biology’s Rosetta Stone
Published in Cellular and molecular neurobiology (01-08-2011)Get full text
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Informed consent of very old patients and modern genomics
Published in Biogerontology (2005)Get full text
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The GTP binding motif: variations on a theme
Published in The FASEB journal (01-10-1996)“…GTP binding proteins (G-proteins) have wide-ranging functions in biology, being involved in cell proliferation, signal transduction, protein synthesis, and…”
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Caspase-1 and Caspase-8 Cleave and Inactivate Cellular Parkin
Published in The Journal of biological chemistry (27-06-2003)“…Lesions in the parkin gene cause early onset Parkinson's disease by a loss of dopaminergic neurons, thus demonstrating a vital role for parkin in the survival…”
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Healthy human ageing
Published in New biotechnology (01-06-2008)Get more information
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Phage-Displayed Antibodies for the Detection of Glycated Proteasome in Aging Cells
Published in Annals of the New York Academy of Sciences (01-05-2006)“…: Accumulation of posttranslationally damaged proteins during aging could explain the decline of cell performance with age. Nɛ‐carboxymethyllysine (CML) is…”
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Understanding and Modulating Ageing
Published in IUBMB life (01-04-2005)“…Ageing is characterized by a progressive accumulation of molecular damage in nucleic acids, proteins and lipids. The inefficiency and failure of maintenance,…”
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New Biotechnology and the European Federation of Biotechnology
Published in New biotechnology (01-06-2008)Get more information
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Understanding and Modulating Aging
Published in Annals of the New York Academy of Sciences (01-05-2006)Get full text
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Identification of Keratinocyte-specific Markers Using Phage Display and Mass Spectrometry
Published in Molecular & cellular proteomics (01-02-2003)“…Specific molecular markers for various normal and pathogenic cell states and cell types provide knowledge of basic biological systems and have a direct…”
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Hormetic action of mild heat stress decreases the inducibility of protein oxidation and glycoxidation in human fibroblasts
Published in Biogerontology (Dordrecht) (2002)“…Repeated mild heat shock (RMHS) has anti-aging effects on growth and various other cellular and biochemical characteristics of human skin fibroblasts…”
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Science fact and the SENS agenda. What can we reasonably expect from ageing research?
Published in EMBO reports (01-11-2005)Get full text
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A Model for the Tertiary Structure of p21, the Product of the ras Oncogene
Published in Science (American Association for the Advancement of Science) (04-10-1985)“…A model was developed for the structure of p21, the protein with a molecular weight of 21,000 that is produced by the ras genes. This model predicts that p21…”
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Functional effects of deleting the coiled‐coil motif in Escherichia coli elongation factor Ts
Published in European journal of biochemistry (01-11-2003)“…Elongation factor Ts (EF‐Ts) is the guanine nucleotide‐exchange factor for elongation factor Tu (EF‐Tu) that is responsible for promoting the binding of…”
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Homologies in the Structures of G-Binding Proteins: An Analysis Based on Elongation Factor EF-TU
Published in Bio/technology (New York, N.Y. 1983) (01-09-1989)Get full text
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The ternary complex of EF-Tu and its role in protein biosynthesis
Published in Current opinion in structural biology (01-02-1997)“…The past year has seen a breakthrough in our structural understanding of how aminoacyl-tRNAs are selected and transported to the ribosomal A-site in order to…”
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