Search Results - "Brian F. C. Clark"

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    Mild heat stress stimulates 20S proteasome and its 11S activator in human fibroblasts undergoing aging in vitro by Beedholm, Rasmus, Clark, Brian F. C., Rattan, Suresh I. S.

    Published in Cell stress & chaperones (01-03-2004)
    “…Repeated mild heat shock (RMHS) has been shown to have several beneficial hormetic effects on human skin fibroblast undergoing aging in vitro. Because an…”
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    Journal Article
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    Kinetin—A multiactive molecule by Barciszewski, Jan, Massino, Frank, Clark, Brian F.C.

    “…Cytokinins are important adenine derivatives that serve as hormones to control many processes in plants. They were discovered as factors that promote cell…”
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    The GTP binding motif: variations on a theme by Kjeldgaard, M, Nyborg, J, Clark, B F

    Published in The FASEB journal (01-10-1996)
    “…GTP binding proteins (G-proteins) have wide-ranging functions in biology, being involved in cell proliferation, signal transduction, protein synthesis, and…”
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    Journal Article
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    Caspase-1 and Caspase-8 Cleave and Inactivate Cellular Parkin by Kahns, Soren, Kalai, Michael, Jakobsen, Lene Diness, Clark, Brian F C, Vandenabeele, Peter, Jensen, Poul Henning

    Published in The Journal of biological chemistry (27-06-2003)
    “…Lesions in the parkin gene cause early onset Parkinson's disease by a loss of dopaminergic neurons, thus demonstrating a vital role for parkin in the survival…”
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    Journal Article
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    Phage-Displayed Antibodies for the Detection of Glycated Proteasome in Aging Cells by GONZALEZ-DOSAL, REGINA, SØRENSEN, MORTEN DRÆBY, CLARK, BRIAN F.C., RATTAN, SURESH I. S., KRISTENSEN, PETER

    Published in Annals of the New York Academy of Sciences (01-05-2006)
    “…:  Accumulation of posttranslationally damaged proteins during aging could explain the decline of cell performance with age. Nɛ‐carboxymethyllysine (CML) is…”
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    Journal Article
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    Understanding and Modulating Ageing by Rattan, Suresh IS, Clark, Brian FC

    Published in IUBMB life (01-04-2005)
    “…Ageing is characterized by a progressive accumulation of molecular damage in nucleic acids, proteins and lipids. The inefficiency and failure of maintenance,…”
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    Identification of Keratinocyte-specific Markers Using Phage Display and Mass Spectrometry by Jensen, Kim Bak, Jensen, Ole Nørregaard, Ravn, Peter, Clark, Brian F C, Kristensen, Peter

    Published in Molecular & cellular proteomics (01-02-2003)
    “…Specific molecular markers for various normal and pathogenic cell states and cell types provide knowledge of basic biological systems and have a direct…”
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    Hormetic action of mild heat stress decreases the inducibility of protein oxidation and glycoxidation in human fibroblasts by VERBEKE, Philippe, DERIES, Marianne, CLARK, Brian F. C, RATTAN, Suresh I. S

    Published in Biogerontology (Dordrecht) (2002)
    “…Repeated mild heat shock (RMHS) has anti-aging effects on growth and various other cellular and biochemical characteristics of human skin fibroblasts…”
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    Conference Proceeding Journal Article
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    A Model for the Tertiary Structure of p21, the Product of the ras Oncogene by McCormick, Frank, Brian F. C. Clark, Troels F. M. la Cour, Kjeldgaard, Morten, Norskov-Lauritsen, Leif, Nyborg, Jens

    “…A model was developed for the structure of p21, the protein with a molecular weight of 21,000 that is produced by the ras genes. This model predicts that p21…”
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    Journal Article
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    Functional effects of deleting the coiled‐coil motif in Escherichia coli elongation factor Ts by Karring, Henrik, Björnsson, Asgeir, Thirup, Søren, Clark, Brian F. C., Knudsen, Charlotte R.

    Published in European journal of biochemistry (01-11-2003)
    “…Elongation factor Ts (EF‐Ts) is the guanine nucleotide‐exchange factor for elongation factor Tu (EF‐Tu) that is responsible for promoting the binding of…”
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    The ternary complex of EF-Tu and its role in protein biosynthesis by Clark, Brian FC, Nyborg, Jens

    Published in Current opinion in structural biology (01-02-1997)
    “…The past year has seen a breakthrough in our structural understanding of how aminoacyl-tRNAs are selected and transported to the ribosomal A-site in order to…”
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