Search Results - "Brewster, Luke"

Frailty increases the risk of 30-day mortality, morbidity, and failure to rescue after elective abdominal aortic aneurysm repair independent of age and comorbidities by Arya, Shipra, MD, SM, Kim, Sung In, BS, Duwayri, Yazan, MD, Brewster, Luke P., MD, PhD, Veeraswamy, Ravi, MD, Salam, Atef, MD, Dodson, Thomas F., MD

“…Background Frailty, defined as a biologic syndrome of decreased reserve and resistance to stressors, has been linked to adverse outcomes after surgery. We…”
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Association of Statin Dose With Amputation and Survival in Patients With Peripheral Artery Disease by Arya, Shipra, Khakharia, Anjali, Binney, Zachary O, DeMartino, Randall R, Brewster, Luke P, Goodney, Philip P, Wilson, Peter W.F

“…BACKGROUND:Statin dose guidelines for patients with peripheral artery disease (PAD) are largely based on coronary artery disease and stroke data. The aim of…”
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Race and Socioeconomic Status Independently Affect Risk of Major Amputation in Peripheral Artery Disease by Arya, Shipra, Binney, Zachary, Khakharia, Anjali, Brewster, Luke P., Goodney, Phil, Patzer, Rachel, Hockenberry, Jason, Wilson, Peter W. F.

“…Background Black race has been shown to be a risk factor for amputation in peripheral artery disease (PAD); however, race has been argued to be a marker for…”
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Perfusion Assessment in Critical Limb Ischemia: Principles for Understanding and the Development of Evidence and Evaluation of Devices: A Scientific Statement From the American Heart Association by Misra, Sanjay, Shishehbor, Mehdi H, Takahashi, Edwin A, Aronow, Herbert D, Brewster, Luke P, Bunte, Matthew C, Kim, Esther S.H, Lindner, Jonathan R, Rich, Kathleen

“…There are >12 million patients with peripheral artery disease in the United States. The most severe form of peripheral artery disease is critical limb ischemia…”
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Poor glycemic control is a strong predictor of postoperative morbidity and mortality in patients undergoing vascular surgery by Long, Chandler A., Fang, Zachary B., Hu, Frances Y., Arya, Shipra, Brewster, Luke P., Duggan, Elizabeth, Duwayri, Yazan

“…Hyperglycemia is a common occurrence in patients undergoing cardiovascular surgery. It has been identified in several surgical cohorts that improved…”
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Gender and frailty predict poor outcomes in infrainguinal vascular surgery by Brahmbhatt, Reshma, MD, Brewster, Luke P., MD, PhD, Shafii, Susan, MD, Rajani, Ravi R., MD, Veeraswamy, Ravi, MD, Salam, Atef, MD, Dodson, Thomas F., MD, Arya, Shipra, MD, SM

“…Abstract Background Women have poorer outcomes after vascular surgery as compared to men as shown by studies recently. Frailty is also an independent risk…”
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High hemoglobin A 1c associated with increased adverse limb events in peripheral arterial disease patients undergoing revascularization by Arya, Shipra, Binney, Zachary O, Khakharia, Anjali, Long, Chandler A, Brewster, Luke P, Wilson, Peter W, Jordan, Jr, William D, Duwayri, Yazan

“…Diabetes and peripheral arterial disease (PAD) are independently associated with increased risk of amputation. However, the effect of poor glycemic control on…”
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Human diabetic mesenchymal stem cells from peripheral arterial disease patients promote angiogenesis through unique secretome signatures by Morris, Andrew D., Dalal, Sidd, Li, Haiyan, Brewster, Luke P.

“…Diabetic patients are at increased risk of complications from severe peripheral arterial disease. Mesenchymal stem cells (MSC) may be useful in limiting these…”
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A novel platelet lysate hydrogel for endothelial cell and mesenchymal stem cell-directed neovascularization by Robinson, Scott T., Douglas, Alison M., Chadid, Tatiana, Kuo, Katie, Rajabalan, Ajai, Li, Haiyan, Copland, Ian B., Barker, Thomas H., Galipeau, Jacques, Brewster, Luke P.

“…[Display omitted] Mesenchymal stem cells (MSC) hold promise in promoting vascular regeneration of ischemic tissue in conditions like critical limb ischemia of…”
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Disturbed Flow Promotes Arterial Stiffening Through Thrombospondin-1 (TSP-1) by Kim, Chan Woo, Pokutta-Paskaleva, Anastassia, Kumar, Sandeep, Timmins, Lucas H, Morris, Andrew D, Kang, Dong-Won, Dalal, Sidd, Chadid, Tatiana, Kuo, Katie M, Raykin, Julia, Li, Haiyan, Yanagisawa, Hiromi, Gleason, Rudolph L, Jo, Hanjoong, Brewster, Luke P

“…BACKGROUND—Arterial stiffness and wall shear stress are powerful determinants of cardiovascular health, and arterial stiffness is associated with increased…”
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Preoperative Frailty Increases Risk of Nonhome Discharge after Elective Vascular Surgery in Home-Dwelling Patients by Arya, Shipra, Long, Chandler A, Brahmbhatt, Reshma, Shafii, Susan, Brewster, Luke P, Veeraswamy, Ravi, Johnson, Theodore M, Johanning, Jason M

“…Background Patient-centered quality outcomes such as disposition after surgery are increasingly being scrutinized. Preoperative factors predictive of nonhome…”
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Myoglobinemia, Peripheral Arterial Disease, and Patient Mortality by Scrivner, Ottis, Fletcher, Emma, Hoffmann, Carson, Li, Feifei, Wilkinson, Trevor, Miserlis, Dimitrios, Smith, Robert S, Bohannon, William T, Sutliff, Roy, Jordan, William D, Koutakis, Panagiotis, Brewster, Luke P

“…Peripheral arterial disease (PAD) causes leg muscle damage due to inadequate perfusion and increases cardiovascular events and mortality 2- to 3-fold. It is…”
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Search Engines to Capture Missing Deaths From Institutional Data Warehouse by Dayal, Yash S, Foster, Dennis G, Hao, Yilun, Bennett, Sasha G, Brewster, Luke P

“…Clinical publications use mortality as a hard end point. It is unknown how many patient deaths are under-reported in institutional databases. The objective of…”
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An endovascular model of ischemic myopathy from peripheral arterial disease by Long, Chandler A., MD, Timmins, Lucas H., PhD, Koutakis, Panagiotis, PhD, Goodchild, Traci T., PhD, Lefer, David J., PhD, Pipinos, Iraklis I., MD, Casale, George P., PhD, Brewster, Luke P., MD, PhD

“…Abstract Objective Peripheral arterial disease (PAD) is a significant age-related medical condition with limited pharmacologic options. Severe PAD, termed…”
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Reversible secretome and signaling defects in diabetic mesenchymal stem cells from peripheral arterial disease patients by Chadid, Tatiana, Morris, Andrew, Surowiec, Alexandra, Robinson, Scott, Sasaki, Maiko, Galipeau, Jacques, Pollack, Brian P., Brewster, Luke P.

“…Regenerative medicine seeks to stall or to reverse the pathologic consequences of chronic diseases. Many people with diabetes have peripheral arterial disease…”
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Hydrogen Sulfide Levels and Nuclear Factor‐Erythroid 2‐Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI) by Islam, Kazi N., Polhemus, David J., Donnarumma, Erminia, Brewster, Luke P., Lefer, David J.

“…Background Cystathionine γ‐lyase, cystathionine β‐synthase, and 3‐mercaptopyruvate sulfurtransferase are endogenous enzymatic sources of hydrogen sulfide…”
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Women undergoing aortic surgery are at higher risk for unplanned readmissions compared with men especially when discharged home by Flink, Benjamin J., MD, MPH, Long, Chandler A., MD, Duwayri, Yazan, MD, Brewster, Luke P., MD, PhD, Veeraswamy, Ravi, MD, Gallagher, Katherine, MD, Arya, Shipra, MD, SM

“…Objective Women undergoing vascular surgery have higher morbidity and mortality. Our study explores gender-based differences in patient-centered outcomes such…”
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Dyslipidemia impairs collateral artery formation after hindlimb ischemia: Adding insult to injury by Hakim, Ali H., Brewster, Luke

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Advances, Pauses, and Future Opportunity for the Prevention of Venous Thromboembolism in the Trauma Population by Ramos, Christopher R, Brewster, Luke P

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NLRP3 Inflammasome Activation in Peripheral Arterial Disease by Bartoli-Leonard, Francesca, Zimmer, Jonas, Sonawane, Abhijeet R, Perez, Katelyn, Turner, Mandy E, Kuraoka, Shiori, Pham, Tan, Li, Feifei, Aikawa, Masanori, Singh, Sasha, Brewster, Luke, Aikawa, Elena

“…Background Peripheral arterial disease (PAD) is estimated to affect 7% of the adult population in the United States; however, there is currently little…”
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