Search Results - "Brewster, C C"
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Promoter architecture dictates cell-to-cell variability in gene expression
Published in Science (American Association for the Advancement of Science) (19-12-2014)“…Variability in gene expression among genetically identical cells has emerged as a central preoccupation in the study of gene regulation; however, a divide…”
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Controlling gene expression timing through gene regulatory architecture
Published in PLoS computational biology (01-01-2022)“…Gene networks typically involve the regulatory control of multiple genes with related function. This connectivity enables correlated control of the levels and…”
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The Transcription Factor Titration Effect Dictates Level of Gene Expression
Published in Cell (13-03-2014)“…Models of transcription are often built around a picture of RNA polymerase and transcription factors (TFs) acting on a single copy of a promoter. However, most…”
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Regulatory properties of transcription factors with diverse mechanistic function
Published in PLoS computational biology (01-06-2024)“…Transcription factors (TFs) regulate the process of transcription through the modulation of different kinetic steps. Although models can often describe the…”
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Tuning promoter strength through RNA polymerase binding site design in Escherichia coli
Published in PLoS computational biology (01-12-2012)“…One of the paramount goals of synthetic biology is to have the ability to tune transcriptional networks to targeted levels of expression at will. As a step in…”
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Tunable transcription factor library for robust quantification of regulatory properties in Escherichia coli
Published in Molecular systems biology (01-06-2022)“…Predicting the quantitative regulatory function of transcription factors (TFs) based on factors such as binding sequence, binding location, and promoter type…”
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Effect of transcription factor resource sharing on gene expression noise
Published in PLoS computational biology (01-04-2017)“…Gene expression is intrinsically a stochastic (noisy) process with important implications for cellular functions. Deciphering the underlying mechanisms of gene…”
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Halomethyl-Triazoles for Rapid, Site-Selective Protein Modification
Published in Molecules (Basel, Switzerland) (08-09-2021)“…Post-translational modifications (PTMs) are used by organisms to control protein structure and function after protein translation, but their study is…”
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The care of patients with an abdominal aortic aneurysm: The Society for Vascular Surgery practice guidelines
Published in Journal of vascular surgery (01-10-2009)Get full text
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Outcomes following endovascular abdominal aortic aneurysm repair (EVAR): An anatomic and device-specific analysis
Published in Journal of vascular surgery (01-07-2008)“…Objective We performed a device-specific comparison of long-term outcomes following endovascular abdominal aortic aneurysm repair (EVAR) to determine the…”
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Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif
Published in eLife (18-08-2020)“…Predicting gene expression from DNA sequence remains a major goal in the field of gene regulation. A challenge to this goal is the connectivity of the network,…”
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Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes
Published in Gut microbes (31-12-2022)“…Psychological stress alters the gut microbiota and predisposes individuals to increased risk for enteric infections and chronic bowel conditions. Intestinal…”
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Guidelines for the treatment of abdominal aortic aneurysms: Report of a subcommittee of the Joint Council of the American Association for Vascular Surgery and Society for Vascular Surgery
Published in Journal of vascular surgery (01-05-2003)“…Decision-making in regard to elective repair of abdominal aortic aneurysms (AAA) requires careful assessment of factors that influence rupture risk, operative…”
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SVS practice guidelines for the care of patients with an abdominal aortic aneurysm: Executive summary
Published in Journal of vascular surgery (01-10-2009)Get full text
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Preoperative variables predict persistent type 2 endoleak after endovascular aneurysm repair
Published in Journal of vascular surgery (01-07-2010)“…Objective Persistent type 2 endoleaks (PT2, present ≥6 months) after endovascular aneurysm repair (EVAR) are associated with adverse outcomes. This study…”
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Race and Ethnicity Reporting and Representation in Pediatric Clinical Trials
Published in Pediatrics (Evanston) (01-04-2023)“…Representative enrollment of racial and ethnic minoritized populations in biomedical research ensures the generalizability of results and equitable access to…”
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Spatial Distribution of Grape Root Borer (Lepidoptera: Sesiidae) Infestations in Virginia Vineyards and Implications for Sampling
Published in Environmental entomology (01-06-2014)“…Grape root borer, Vitacea polistiformis (Harris) (Lepidoptera: Sesiidae) is a potentially destructive pest of grape vines, Vitis spp. in the eastern United…”
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Effects of La Crosse virus infection on the host-seeking behavior and levels of two neurotransmitters in Aedes triseriatus
Published in Parasites & vectors (09-08-2019)“…La Crosse virus (LACV) infection has been shown to manipulate the blood-feeding behaviors of its main vector, Aedes triseriatus. Here, we investigated the…”
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Persistent Lactic Acidosis in an Infant With Milk Protein Allergy
Published in Clinical pediatrics (01-09-2023)Get full text
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