Search Results - "Brewster, C C"

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    Promoter architecture dictates cell-to-cell variability in gene expression by Jones, Daniel L., Brewster, Robert C., Phillips, Rob

    “…Variability in gene expression among genetically identical cells has emerged as a central preoccupation in the study of gene regulation; however, a divide…”
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    Journal Article
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    Controlling gene expression timing through gene regulatory architecture by Ali, Md Zulfikar, Brewster, Robert C

    Published in PLoS computational biology (01-01-2022)
    “…Gene networks typically involve the regulatory control of multiple genes with related function. This connectivity enables correlated control of the levels and…”
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    Journal Article
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    The Transcription Factor Titration Effect Dictates Level of Gene Expression by Brewster, Robert C., Weinert, Franz M., Garcia, Hernan G., Song, Dan, Rydenfelt, Mattias, Phillips, Rob

    Published in Cell (13-03-2014)
    “…Models of transcription are often built around a picture of RNA polymerase and transcription factors (TFs) acting on a single copy of a promoter. However, most…”
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    Journal Article
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    Regulatory properties of transcription factors with diverse mechanistic function by Ali, Md Zulfikar, Guharajan, Sunil, Parisutham, Vinuselvi, Brewster, Robert C

    Published in PLoS computational biology (01-06-2024)
    “…Transcription factors (TFs) regulate the process of transcription through the modulation of different kinetic steps. Although models can often describe the…”
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    Journal Article
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    Tuning promoter strength through RNA polymerase binding site design in Escherichia coli by Brewster, Robert C, Jones, Daniel L, Phillips, Rob

    Published in PLoS computational biology (01-12-2012)
    “…One of the paramount goals of synthetic biology is to have the ability to tune transcriptional networks to targeted levels of expression at will. As a step in…”
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    Journal Article
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    Tunable transcription factor library for robust quantification of regulatory properties in Escherichia coli by Parisutham, Vinuselvi, Chhabra, Shivani, Ali, Md Zulfikar, Brewster, Robert C

    Published in Molecular systems biology (01-06-2022)
    “…Predicting the quantitative regulatory function of transcription factors (TFs) based on factors such as binding sequence, binding location, and promoter type…”
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    Journal Article
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    Effect of transcription factor resource sharing on gene expression noise by Das, Dipjyoti, Dey, Supravat, Brewster, Robert C, Choubey, Sandeep

    Published in PLoS computational biology (01-04-2017)
    “…Gene expression is intrinsically a stochastic (noisy) process with important implications for cellular functions. Deciphering the underlying mechanisms of gene…”
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    Journal Article
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    Halomethyl-Triazoles for Rapid, Site-Selective Protein Modification by Brewster, Richard C., Hulme, Alison N.

    Published in Molecules (Basel, Switzerland) (08-09-2021)
    “…Post-translational modifications (PTMs) are used by organisms to control protein structure and function after protein translation, but their study is…”
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    Outcomes following endovascular abdominal aortic aneurysm repair (EVAR): An anatomic and device-specific analysis by Abbruzzese, Thomas A., MD, Kwolek, Christopher J., MD, Brewster, David C., MD, Chung, Thomas K., MS, Kang, Jeanwan, MD, Conrad, Mark F., MD, LaMuraglia, Glenn M., MD, Cambria, Richard P., MD

    Published in Journal of vascular surgery (01-07-2008)
    “…Objective We performed a device-specific comparison of long-term outcomes following endovascular abdominal aortic aneurysm repair (EVAR) to determine the…”
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    Journal Article
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    Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif by Ali, Md Zulfikar, Parisutham, Vinuselvi, Choubey, Sandeep, Brewster, Robert C

    Published in eLife (18-08-2020)
    “…Predicting gene expression from DNA sequence remains a major goal in the field of gene regulation. A challenge to this goal is the connectivity of the network,…”
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    Journal Article
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    Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes by Allen, Jacob M., Mackos, Amy R., Jaggers, Robert M., Brewster, Patricia C., Webb, Mikaela, Lin, Chia-Hao, Ladaika, Chris, Davies, Ronald, White, Peter, Loman, Brett R., Bailey, Michael T.

    Published in Gut microbes (31-12-2022)
    “…Psychological stress alters the gut microbiota and predisposes individuals to increased risk for enteric infections and chronic bowel conditions. Intestinal…”
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    Journal Article
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    Guidelines for the treatment of abdominal aortic aneurysms: Report of a subcommittee of the Joint Council of the American Association for Vascular Surgery and Society for Vascular Surgery by Brewster, David C., Cronenwett, Jack L., Hallett, John W., Johnston, K.Wayne, Krupski, William C., Matsumura, Jon S.

    Published in Journal of vascular surgery (01-05-2003)
    “…Decision-making in regard to elective repair of abdominal aortic aneurysms (AAA) requires careful assessment of factors that influence rupture risk, operative…”
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    Journal Article
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    Preoperative variables predict persistent type 2 endoleak after endovascular aneurysm repair by Abularrage, Christopher J., MD, Crawford, Robert S., MD, Conrad, Mark F., MD, MMSc, Lee, Hang, PhD, Kwolek, Christopher J., MD, Brewster, David C., MD, Cambria, Richard P., MD, LaMuraglia, Glenn M., MD

    Published in Journal of vascular surgery (01-07-2010)
    “…Objective Persistent type 2 endoleaks (PT2, present ≥6 months) after endovascular aneurysm repair (EVAR) are associated with adverse outcomes. This study…”
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    Journal Article Conference Proceeding
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    Race and Ethnicity Reporting and Representation in Pediatric Clinical Trials by Brewster, Ryan C L, Steinberg, Jecca R, Magnani, Christopher J, Jackson, Jasmyne, Wong, Bonnie O, Valikodath, Nishma, MacDonald, Justin, Li, Anna, Marsland, Paula, Goodman, Steven N, Schroeder, Alan, Turner, Brandon

    Published in Pediatrics (Evanston) (01-04-2023)
    “…Representative enrollment of racial and ethnic minoritized populations in biomedical research ensures the generalizability of results and equitable access to…”
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    Journal Article
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    Spatial Distribution of Grape Root Borer (Lepidoptera: Sesiidae) Infestations in Virginia Vineyards and Implications for Sampling by Rijal, J. P, Brewster, C. C, Bergh, J. C

    Published in Environmental entomology (01-06-2014)
    “…Grape root borer, Vitacea polistiformis (Harris) (Lepidoptera: Sesiidae) is a potentially destructive pest of grape vines, Vitis spp. in the eastern United…”
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    Journal Article
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    Effects of La Crosse virus infection on the host-seeking behavior and levels of two neurotransmitters in Aedes triseriatus by Yang, Fan, Chan, Kevin, Brewster, Carlyle C, Paulson, Sally L

    Published in Parasites & vectors (09-08-2019)
    “…La Crosse virus (LACV) infection has been shown to manipulate the blood-feeding behaviors of its main vector, Aedes triseriatus. Here, we investigated the…”
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    Journal Article
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