Search Results - "Brewer, Kori L"
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Dopamine D1 and D3 receptor modulators restore morphine analgesia and prevent opioid preference in a model of neuropathic pain
Published in Neuroscience (15-05-2019)“…A secondary consequence of spinal cord injury (SCI) is debilitating chronic neuropathic pain, which is commonly morphine resistant and inadequately managed by…”
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2
A novel opioid/pramipexole combination treatment for the management of acute pain: a pilot study
Published in Frontiers in pain research (Lausanne, Switzerland) (24-09-2024)“…Despite their dangerous side effects, opioid drugs remain a standard of care for moderate to severe pain with few alternatives. Strategies to maintain the…”
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Retrospective chart review of substance abuse in patients with psychiatric emergencies in an emerging urban county
Published in Journal of the American College of Emergency Physicians Open (01-08-2023)“…Objectives Substance abuse is common in patients with psychiatric emergencies. To further understand the connection between substance abuse and psychiatric…”
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Neuroscience Near-Peer-Led Flipped Classroom Improves Student Confidence With Clinical Application of Content and Test-Taking Skills
Published in MedEdPORTAL (25-03-2021)“…The ability to apply knowledge gained in neuroscience coursework to a clinical scenario is found to be difficult by many medical students. Neuroscience is both…”
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5
Dopamine D3 receptor dysfunction prevents anti-nociceptive effects of morphine in the spinal cord
Published in Frontiers in neural circuits (11-06-2014)“…Dopamine (DA) modulates spinal reflexes, including nociceptive reflexes, in part via the D3 receptor subtype. We have previously shown that mice lacking the…”
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Injectable Lidocaine Provides Similar Analgesia Compared to Transdermal Lidocaine/Tetracaine Patch for the Incision and Drainage of Skin Abscesses: A Randomized, Controlled Trial
Published in The Journal of emergency medicine (01-09-2014)“…Abstract Background Local anesthesia used for incision and drainage of abscesses is known to be painful. Study Objective We studied the analgesia provided by a…”
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Naltrexone prevents delayed encephalopathy in rats poisoned with the sarin analogue diisopropylflurophosphate
Published in The American journal of emergency medicine (01-04-2013)“…Abstract Background Acute poisoning with organophosphate compounds can cause chronic neuropsychological disabilities not prevented by standard antidotes of…”
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Location of the Appendix in the Gravid Patient
Published in The Journal of emergency medicine (01-05-2014)“…Abstract Background Several studies have attempted to support or dispel the teaching of appendix movement away from the right lower quadrant (RLQ) during…”
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Long-term efficacy of pressure immobilization bandages in a porcine model of coral snake envenomation
Published in The American journal of emergency medicine (01-09-2014)“…Abstract Background Pressure immobilization bandages delay mortality for 8 hours after coral snake envenomation, but long-term efficacy has not been…”
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10
The authors respond: Anti venom cost issues
Published in The American journal of emergency medicine (01-02-2024)“…5)We thank the Letter's authors for giving us the opportunity to re-review our data that resulted in no changes to our findings and further emphasized the…”
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Comparing cost of F(.ab’)2AV vs FabAV in the treatment of copperhead envenomation–One center's experience
Published in The American journal of emergency medicine (01-11-2023)“…The definitive treatment of North American crotalid snakebites is antivenin. In 2000, an FabAV antivenom (CroFab®) was introduced and in 2022, F(ab’)2AV…”
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Agmatine Reverses Pain Induced by Inflammation, Neuropathy, and Spinal Cord Injury
Published in Proceedings of the National Academy of Sciences - PNAS (12-09-2000)“…Antagonists of glutamate receptors of the N-methyl-D-aspartate subclass (NMDAR) or inhibitors of nitric oxide synthase (NOS) prevent nervous system plasticity…”
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Morphine Resistance in Spinal Cord Injury-Related Neuropathic Pain in Rats is Associated With Alterations in Dopamine and Dopamine-Related Metabolomics
Published in The journal of pain (01-05-2022)“…Opioids are not universally effective for treating neuropathic pain following spinal cord injury (SCI), a finding that we previously demonstrated in a rat…”
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Estimation of laceration length by emergency department personnel
Published in The western journal of emergency medicine (01-11-2014)“…Documentation and billing for laceration repair involves a description of wound length. We designed this study to test the hypothesis that emergency department…”
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Dopamine D 1 or D 3 receptor modulators prevent morphine tolerance and reduce opioid withdrawal symptoms
Published in Pharmacology, biochemistry and behavior (01-07-2020)“…The long-term treatment of chronic pain by opioids is limited by tolerance and risk of addiction/dependence. Previously, we have shown that combination…”
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A Localizing Circumferential Compression Device Increases Survival after Coral Snake Envenomation to the Torso of an Animal Model
Published in The Journal of emergency medicine (01-07-2011)“…Abstract Background: Pressure immobilization bandages have been shown to delay onset of systemic toxicity after Eastern coral snake ( Micrurus fulvius )…”
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Can clinical prediction rules used in acute pediatric ankle and midfoot injuries be applied to an adult population?
Published in The American journal of emergency medicine (01-05-2011)“…Abstract Background Almost every patient who comes to an emergency department (ED) with the chief complaint of ankle or foot pain will receive a radiograph,…”
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Predifferentiated embryonic stem cells prevent chronic pain behaviors and restore sensory function following spinal cord injury in mice
Published in Molecular medicine (Cambridge, Mass.) (01-01-2006)“…Embryonic stem (ES) cells have been investigated in repair of the CNS following neuronal injury and disease; however, the efficacy of these cells in treatment…”
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Predicting opioid use disorder in patients with chronic pain who present to the emergency department
Published in Injury prevention (01-10-2019)“…Emergency department (ED) patients with chronic pain challenge providers to make quick and accurate assessments without an in-depth pain management…”
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Estimating clinical research project duration from idea to publication
Published in Journal of investigative medicine (01-01-2022)“…Of 39 eligible publications, we reconstructed study timelines (table 1) for 17 publications based on departmental records, and 10 publications based on a…”
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