Search Results - "Brewer, C Trent"
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PXR variants:the impact on drug metabolism and therapeutic responses
Published in Acta pharmaceutica Sinica. B (01-09-2016)“…The pregnane X receptor(PXR) plays an important and diverse role in mediating xenobiotic induction of drug-metabolizing enzymes and transporters.Several…”
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High-Throughput Imaging of PPIX Using Confocal Microscopy
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2019)“…Increases in levels of protoporphyrin IX (PPIX; a heme precursor) may be driven by xenobiotic induction of aminolevulinic acid synthase 1 (ALAS1) expression…”
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Glucose-dependent regulation of pregnane X receptor is modulated by AMP-activated protein kinase
Published in Scientific reports (24-04-2017)“…Pregnane X receptor (PXR) is a xenobiotic receptor that regulates the detoxification and clearance of drugs and foreign compounds from the liver. There has…”
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