Search Results - "Breuer, Matthew R."

The Antidepressant Sertraline Induces the Formation of Supersized Lipid Droplets in the Human Pathogen Cryptococcus neoformans by Breuer, Matthew R., Dasgupta, Ananya, Vasselli, Joseph G., Lin, Xiaorong, Shaw, Brian D., Sachs, Matthew S.

“…The prevalence and increasing incidence of fungal infections globally is a significant worldwide health problem. Cryptococcosis, primarily caused by the…”
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The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases by Stukey, Geordan J, Breuer, Matthew R, Burchat, Natalie, Jog, Ruta, Schultz, Kollin, Han, Gil-Soo, Sachs, Matthew S, Sampath, Harini, Marmorstein, Ronen, Carman, George M

“…Phosphatidic acid phosphatase (PAP) is an evolutionarily conserved eukaryotic enzyme that catalyzes the Mg2+-dependent dephosphorylation of phosphatidic acid…”
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