Search Results - "Breuer, Marco L"

Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death by Migchielsen, Alexandra A.J, Breuer, Marco L, van Roon, Marian A, Riele, Hein te, Zurcher, Chris, Ossendorp, Ferry, Toutain, Stephan, Hershfield, Michael S, Berns, Anton, Valerio, Dinko

“…We report the generation and characterization of mice lacking adenosine deaminase (ADA). In humans, absence of ADA causes severe combined immunodeficiency. In…”
Get full text

Total synthesis and absolute configuration of the natural dipeptide .gamma.-glutamylmarasmine by Van den Broek, Leon A. G. M, Breuer, Marco L, Liskamp, Rob M. J, Ottenheijm, Harry C. J

Get full text

Both Lipolysis and Hepatic Uptake of VLDL Are Impaired in Transgenic Mice Coexpressing Human Apolipoprotein E3Leiden and Human Apolipoprotein C1 by Jong, Miek C, Dahlmans, Vivian E.H, van Gorp, Patrick J.J, Breuer, Marco L, Mol, Marc J.T.M, van der Zee, Andre, Frants, Rune R, Hofker, Marten H, Havekes, Louis M

“…Transgenic mice overexpressing human APOE*3Leiden are highly susceptible to diet-induced hyperlipoproteinemia and atherosclerosis due to a defect in hepatic…”
Get full text

In the Absence of Endogenous Mouse Apolipoprotein E, Apolipoprotein E2(Arg-158 → Cys) Transgenic Mice Develop More Severe Hyperlipoproteinemia than Apolipoprotein E3-Leiden Transgenic Mice by van Vlijmen, Bart J.M., van Dijk, Ko Willems, van't Hof, H. Belinda, van Gorp, Patrick J.J., van der Zee, André, van der Boom, Hans, Breuer, Marco L., Hofker, Marten H., Havekes, Louis M.

“…Apolipoprotein E*2(Arg-158 → Cys) (APOE*2) transgenic mice were generated and compared to the previously generated apolipoprotein E*3-Leiden (APOE*3-Leiden)…”
Get full text

The genetic background modifies the spontaneous and X-ray-induced tumor spectrum in theApc1638N mouse model by van der Houven van Oordt, C. Willemien, Smits, Ron, Schouten, Theo G., Houwing-Duistermaat, Jeanine J., Williamson, Sophia L.H., Luz, Arne, Khan, P. Meera, van der Eb, Alex J., Breuer, Marco L., Fodde, Riccardo

Get full text

In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway by Jong, M C, Dahlmans, V E, van Gorp, P J, van Dijk, K W, Breuer, M L, Hofker, M H, Havekes, L M

“…To study the role of apoC1 in lipoprotein metabolism, we have generated transgenic mice expressing the human APOC1 gene. On a sucrose-rich diet, male…”
Get full text

Generation of transgenic mice by Hofker, M H, Breuer, M

Get more information

The genetic background modifies the spontaneous and X-ray-induced tumor spectrum in the Apc1638N mouse model by van der Houven van Oordt, C. Willemien, Smits, Ron, Schouten, Theo G., Houwing-Duistermaat, Jeanine J., Williamson, Sophia L.H., Luz, Arne, Khan, P. Meera, van der Eb, Alex J., Breuer, Marco L., Fodde, Riccardo

“…The effect of the genetic background on the tumor spectrum of Apc1638N, a mouse model for attenuated familial adenomatous polyposis (FAP), has been…”
Get full text

Full Genetic Rescue of Adenosine Deaminase-Deficient Mice Through Introduction of the Human Gene by Migchielsen, Alexandra A. J., Breuer, Marco L., Hershfield, Michael S., Valerio, Dinko

“…We have shown recently that adenosine deaminase (ADA)-deficient mice die perinatally with severe liver cell degeneration. In addition to enzyme substitution,…”
Get full text

Differentially expressed transcripts in x-ray induced lymphomas identified by dioxygenin-labeled differential display by van der Houven van Oordt, C. Willemien, Schouten, Theo G., van der Eb, Alex J., Breuer, Marco L.

“…Differential display is an easily applied method for comparing gene expression in a variety of systems. We used a nonradioactive differential display technique…”
Get full text

Developmental expression of crystallin genes: In situ hybridization reveals a differential localization of specific mRNAs by Van Leen, Rob W., Breuer, Marco L., Lubsen, Nicolette H., Schoenmakers, John G.G.

“…The time and place of the accumulation of αA-, βB1- and γ-crystallin RNA in the developing rat lens have been studied by in situ hybridization. αA- and…”
Get full text

Comparative analysis of the human and feline c-sis proto-oncogenes. Identification of 5' human c-sis coding sequences that are not homologous to the transforming gene of simian sarcoma virus by van den Ouweland, A M, Breuer, M L, Steenbergh, P H, Schalken, J A, Bloemers, H P, Van de Ven, W J

“…Feline and human genetic sequences, homologous to the v-sis gene of simian sarcoma virus, have been isolated from cosmid gene libraries and characterized by…”
Get more information