Search Results - "Bretz, Niko P"

Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling by Bretz, Niko P., Ridinger, Johannes, Rupp, Anne-Kathleen, Rimbach, Katharina, Keller, Sascha, Rupp, Christian, Marmé, Frederik, Umansky, Ludmila, Umansky, Viktor, Eigenbrod, Tatjana, Sammar, Marei, Altevogt, Peter

“…Tumor-derived exosomes have been shown to induce various immunomodulatory effects. However, the underlying signaling pathways are poorly understood. Here, we…”
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The CD24 surface antigen in neural development and disease by Gilliam, Daniel T, Menon, Vishal, Bretz, Niko P, Pruszak, Jan

“…Abstract A cell ' s surface molecular signature enables its reciprocal interactions with the associated microenvironments in development, tissue homeostasis…”
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CD24 controls Src/STAT3 activity in human tumors by Bretz, Niko P., Salnikov, Alexei V., Perne, Claudia, Keller, Sascha, Wang, Xiaoli, Mierke, Claudia T., Fogel, Mina, Erbe-Hofmann, Natalie, Schlange, Thomas, Moldenhauer, Gerhard, Altevogt, Peter

“…CD24 is a glycosyl-phosphatidylinositol-anchored membrane protein that is frequently over-expressed in a variety of human carcinomas and is correlated with…”
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miR-21-3p is a positive regulator of L1CAM in several human carcinomas by Doberstein, Kai, Bretz, Niko P, Schirmer, Uwe, Fiegl, Heidi, Blaheta, Roman, Breunig, Christian, Müller-Holzner, Elisabeth, Reimer, Dan, Zeimet, Alain G, Altevogt, Peter

“…Highlights • miR-21-3p is a positive regulator of L1CAM expression. • In patients we observed a strong positive correlation of L1CAM and miR-21-3p. • Although…”
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Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma by Schirmer, Uwe, Doberstein, Kai, Rupp, Anne-Kathleen, Bretz, Niko P, Wuttig, Daniela, Kiefel, Helena, Breunig, Christian, Fiegl, Heidi, Müller-Holzner, Elisabeth, Zeillinger, Robert, Schuster, Eva, Zeimet, Alain G, Sültmann, Holger, Altevogt, Peter

“…L1CAM promotes cell motility, invasion and metastasis formation in various human cancers and can be considered as a driver of tumor progression. Knowledge…”
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Novel insights into exosome-induced, tumor-associated inflammation and immunomodulation by Altevogt, Peter, Bretz, Niko P, Ridinger, Johannes, Utikal, Jochen, Umansky, Viktor

“…Abstract The immune system of cancer patients is often suppressed. Accumulating evidence suggests that exosomes released from tumor cells may play an essential…”
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Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT by Doberstein, Kai, Harter, Patrick N., Haberkorn, Uwe, Bretz, Niko P., Arnold, Bernd, Carretero, Rafael, Moldenhauer, Gerhard, Mittelbronn, Michel, Altevogt, Peter

“…L1 cell adhesion molecule (L1CAM) is overexpressed in many human cancers, confers bad prognosis and augments cell motility, invasion and metastasis. Results…”
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L1CAM is expressed in triple-negative breast cancers and is inversely correlated with androgen receptor by Doberstein, Kai, Milde-Langosch, Karin, Bretz, Niko P, Schirmer, Uwe, Harari, Ayelet, Witzel, Isabell, Ben-Arie, Alon, Hubalek, Michael, Müller-Holzner, Elisabeth, Reinold, Susanne, Zeimet, Alain G, Altevogt, Peter, Fogel, Mina

“…Breast cancer is a heterogeneous disease displaying distinct molecular features and clinical outcome. The molecular profile of triple-negative breast cancers…”
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Lack of CD24 expression in mice reduces the number of leukocytes in the colon by Bretz, Niko P, Salnikov, Alexei V, Doberstein, Kai, Garbi, Natalio, Kloess, Volker, Joumaa, Safwan, Naumov, Inna, Boon, Louis, Moldenhauer, Gerhard, Arber, Nadir, Altevogt, Peter

“…Highlights • We compared leukocytes in organs of CD24−/− vs. wildtype mice. • Highly decreased numbers of leukocytes in colons of CD24−/− mice were detected. •…”
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Abstract B3: CD24 affects tumor cell properties and cytokine secretion in a STAT3-dependent fashion by Bretz, Niko P., Salnikov, Alexei V., Moldenhauer, Gerhard, Altevogt, Peter

“…CD24 is a glycosyl-phosphatidylinositol (GPI)-anchored membrane protein frequently over-expressed in human carcinomas and associated with metastasis and poor…”
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Abstract 3087: CD24 regulates tumor cell behaviour in a c-Src dependent fashion by Bretz, Niko P., Schlange, Thomas, Salnikov, Alexei V., Noske, Aurelia, Perne, Claudia, Moldenhauer, Gerhard, Kristiansen, Glen, Altevogt, Peter

“…CD24 is a glycosyl phosphatidylinositol (GPI)-anchored membrane protein that is frequently over-expressed in a variety of human carcinomas and is correlated…”
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