Search Results - "Breton, V."
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Prenatal Tobacco Smoke Exposure Affects Global and Gene-specific DNA Methylation
Published in American journal of respiratory and critical care medicine (01-09-2009)“…Prenatal exposure to tobacco smoke increases the risk for diseases later in the child's life that may be mediated through alterations in DNA methylation. To…”
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Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults
Published in Environment international (01-12-2020)“…•Per- and polyfluoroalkyl substances (PFASs) are associated with glucose intolerance.•PFAS is associated with increased lipolysis.•Lipid metabolism may…”
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Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group
Published in Environmental health perspectives (01-04-2017)“…Characterization of the epigenome is a primary interest for children's environmental health researchers studying the environmental influences on human…”
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Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium
Published in Diabetes care (01-01-2020)“…Maternal gestational diabetes mellitus (GDM) has been associated with adverse outcomes in the offspring. Growing evidence suggests that the epigenome may play…”
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Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships
Published in Human genetics (01-10-2012)“…Changes in epigenetic marks such as DNA methylation and histone acetylation are associated with a broad range of disease traits, including cancer, asthma,…”
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GPS-derived environmental exposures during pregnancy and early postpartum – Evidence from the madres cohort
Published in The Science of the total environment (25-03-2024)“…The built and natural environment factors (e.g., greenspace, walkability) are associated with maternal and infant health during and after pregnancy. Most…”
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Prenatal metal(loid) mixtures and birth weight for gestational age: A pooled analysis of three cohorts participating in the ECHO program
Published in Environment international (01-03-2022)“…[Display omitted] A growing number of studies have identified both toxic and essential metals which influence fetal growth. However, most studies have…”
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Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children
Published in Journal of allergy and clinical immunology (01-01-2012)“…Background Inducible nitric oxide synthase (iNOS; encoded by nitric oxide synthase isoform 2 [NOS2] ) is the major enzyme for nitric oxide synthesis in…”
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Exploring the evidence for epigenetic regulation of environmental influences on child health across generations
Published in Communications biology (22-06-2021)“…Environmental exposures, psychosocial stressors and nutrition are all potentially important influences that may impact health outcomes directly or via…”
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Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis
Published in Epigenetics (31-12-2023)“…The placenta undergoes many changes throughout gestation to support the evolving needs of the foetus. There is also a growing appreciation that male and female…”
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Extracellular vesicle-enriched miRNA profiles across pregnancy in the MADRES cohort
Published in PloS one (12-05-2021)“…MicroRNA (miRNA) circulating in plasma have been proposed as biomarkers for a variety of conditions and diseases, including complications during pregnancy…”
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Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation
Published in PloS one (25-06-2014)“…Smoking while pregnant is associated with a myriad of negative health outcomes in the child. Some of the detrimental effects may be due to epigenetic…”
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Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort
Published in Epigenetics (03-10-2022)“…Exposure to metals increases risk for pregnancy complications. Extracellular vesicle (EV) miRNA contribute to maternal-foetal communication and are…”
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Prenatal ambient air pollution exposure and child weight trajectories from the 3rd trimester of pregnancy to 2 years of age: a cohort study
Published in BMC medicine (07-09-2023)“…Prenatal air pollution exposure may increase risk for childhood obesity. However, few studies have evaluated in utero growth measures and infant weight…”
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Dietary Arsenic Exposure in Bangladesh
Published in Environmental health perspectives (01-06-2007)“…Background: Millions of people in Bangladesh are at risk of chronic arsenic toxicity from drinking contaminated groundwater, but little is known about diet as…”
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Effects of in-utero personal exposure to PM2.5 sources and components on birthweight
Published in Scientific reports (11-12-2023)“…In-utero exposure to fine particulate matter (PM 2.5 ) and specific sources and components of PM 2.5 have been linked with lower birthweight. However, previous…”
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Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults
Published in PloS one (07-03-2016)“…Exposure to ambient air pollutants increases risk for adverse cardiovascular health outcomes in adults. We aimed to evaluate the contribution of prenatal air…”
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Maternal glucose levels and late pregnancy circulating extracellular vesicle and particle miRNAs in the MADRES pregnancy cohort
Published in Epigenetics (01-12-2024)“…Maternal hyperglycemia during pregnancy adversely affects maternal and child outcomes. While mechanisms are not fully understood, maternal circulating miRNAs…”
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Perceptions and experiences of environmental health and risks among Latina mothers in urban Los Angeles, California, USA
Published in Environmental health (14-01-2023)“…Environmental exposures during pregnancy and early childhood can have acute and chronic adverse health impacts. As minoritized populations are more likely to…”
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Effect of parental adverse childhood experiences on intergenerational DNA methylation signatures from peripheral blood mononuclear cells and buccal mucosa
Published in Translational psychiatry (12-02-2024)“…In this study, the effect of cumulative ACEs experienced on human maternal DNA methylation (DNAm) was estimated while accounting for interaction with domains…”
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