Search Results - "Bressler, Neil M"

Automated Grading of Age-Related Macular Degeneration From Color Fundus Images Using Deep Convolutional Neural Networks by Burlina, Philippe M, Joshi, Neil, Pekala, Michael, Pacheco, Katia D, Freund, David E, Bressler, Neil M

“…Age-related macular degeneration (AMD) affects millions of people throughout the world. The intermediate stage may go undetected, as it typically is…”
Get more information

Deep learning in ophthalmology: The technical and clinical considerations by Ting, Daniel S.W., Peng, Lily, Varadarajan, Avinash V., Keane, Pearse A., Burlina, Philippe M., Chiang, Michael F., Schmetterer, Leopold, Pasquale, Louis R., Bressler, Neil M., Webster, Dale R., Abramoff, Michael, Wong, Tien Y.

“…The advent of computer graphic processing units, improvement in mathematical models and availability of big data has allowed artificial intelligence (AI) using…”
Get full text

Comparing Humans and Deep Learning Performance for Grading AMD: A Study in Using Universal Deep Features and Transfer Learning for Automated AMD Analysis by Burlina, Philippe, Pacheco, Katia D, Joshi, Neil, Freund, David E, Bressler, Neil M

“…Abstract Background: When left untreated, age-related macular degeneration (AMD) is the leading cause of vision loss in people over fifty in the US. Currently…”
Get full text

Prevalence of and risk factors for diabetic macular edema in the United States by Varma, Rohit, Bressler, Neil M, Doan, Quan V, Gleeson, Michelle, Danese, Mark, Bower, Julie K, Selvin, Elizabeth, Dolan, Chantal, Fine, Jennifer, Colman, Shoshana, Turpcu, Adam

“…Diabetic macular edema (DME) is a leading cause of vision loss in persons with diabetes mellitus. Although there are national estimates for the prevalence of…”
Get more information

Antiangiogenic Approaches to Age-Related Macular Degeneration Today by Bressler, Neil M., MD

“…Intravitreal ranibizumab reduces the risk of visual acuity loss and increases the chance of visual acuity gain compared with no treatment or photodynamic…”
Get full text

Immunogenicity With Ranibizumab Biosimilar SB11 (Byooviz) and Reference Product Lucentis and Association With Efficacy, Safety, and Pharmacokinetics: A Post Hoc Analysis of a Phase 3 Randomized Clinical Trial by Bressler, Neil M, Kim, Taehyung, Oh, Inkyung, Russo, Paola, Kim, Mercy Yeeun, Woo, Se Joon

“…SB11 and reference ranibizumab (RBZ) are monoclonal anti-vascular endothelial growth factor (VEGF)-A antibodies approved for the treatment of neovascular…”
Get more information

Expanded 2-Year Follow-up of Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema by Elman, Michael J., MD, Bressler, Neil M., MD, Qin, Haijing, MS, Beck, Roy W., MD, PhD, Ferris, Frederick L., MD, Friedman, Scott M., MD, Glassman, Adam R., MS, Scott, Ingrid U., MD, MPH, Stockdale, Cynthia R., MSPH, Sun, Jennifer K., MD, MPH

“…Objective To report expanded 2-year follow-up of a previously reported randomized trial evaluating intravitreal 0.5 mg ranibizumab or 4 mg triamcinolone…”
Get full text

Intravitreal Ranibizumab for Diabetic Macular Edema with Prompt versus Deferred Laser Treatment: 5-Year Randomized Trial Results by Elman, Michael J., MD, Ayala, Allison, MS, Bressler, Neil M., MD, Browning, David, MD, Flaxel, Christina J., MD, Glassman, Adam R., MS, Jampol, Lee M., MD, Stone, Thomas W., MD

“…Objective To report 5-year results from a previously reported trial evaluating intravitreal 0.5 mg ranibizumab with prompt versus deferred (for ≥24 weeks)…”
Get full text

Randomized Trial Evaluating Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema by Elman, Michael J., MD, Aiello, Lloyd Paul, MD, PhD, Beck, Roy W., MD, PhD, Bressler, Neil M., MD, Bressler, Susan B., MD, Edwards, Allison R., MS, Ferris, Frederick L., MD, Friedman, Scott M., MD, Glassman, Adam R., MS, Miller, Kellee M., MPH, Scott, Ingrid U., MD, MPH, Stockdale, Cynthia R., MSPH, Sun, Jennifer K., MD, MPH

“…Objective Evaluate intravitreal 0.5 mg ranibizumab or 4 mg triamcinolone combined with focal/grid laser compared with focal/grid laser alone for treatment of…”
Get full text

Sensitivity and Specificity of Potential Diagnostic Features Detected Using Fundus Photography, Optical Coherence Tomography, and Fluorescein Angiography for Polypoidal Choroidal Vasculopathy by Chaikitmongkol, Voraporn, Kong, Jun, Khunsongkiet, Preeyanuch, Patikulsila, Direk, Sachdeva, Mira, Chavengsaksongkram, Pimploy, Dejkriengkraikul, Chutikarn, Winaikosol, Pawara, Choovuthayakorn, Janejit, Watanachai, Nawat, Kunavisarut, Paradee, Ingviya, Thammasin, Bressler, Neil M

“…The use of indocyanine green angiography (ICGA) is a criterion standard for diagnosing polypoidal choroidal vasculopathy (PCV), an endemic and common cause of…”
Get more information

Recent clinically relevant highlights from the Diabetic Retinopathy Clinical Research Network by Krick, Tracy W, Bressler, Neil M

“…PURPOSE OF REVIEWTo present some recent clinically relevant results from Diabetic Retinopathy Clinical Research (DRCR) Network trials that may guide management…”
Get full text

Visual acuity time in range: a novel concept to describe consistency in treatment response in diabetic macular oedema by Kozak, Igor, Pearce, Ian, Cheung, Chui Ming Gemmy, Machewitz, Tobias, Lambrou, George N., Molina, Daniel, Suleiman, Lima, Youssef, Hossam, Bressler, Neil M.

“…Objective To assess ‘time in range’ as a novel measure of treatment response in diabetic macular oedema (DMO). Methods This post hoc analysis of the Protocol T…”
Get full text

Repeated intravitreous ranibizumab injections for diabetic macular edema and the risk of sustained elevation of intraocular pressure or the need for ocular hypotensive treatment by Bressler, Susan B, Almukhtar, Talat, Bhorade, Anjali, Bressler, Neil M, Glassman, Adam R, Huang, Suber S, Jampol, Lee M, Kim, Judy E, Melia, Michele

“…For the management of retinal disease, the use of intravitreous injections of anti-vascular endothelial growth factor has increased. Recent reports have…”
Get more information

Development of a new Rasch-based scoring algorithm for the National Eye Institute Visual Functioning Questionnaire to improve its interpretability by Petrillo, Jennifer, Bressler, Neil M, Lamoureux, Ecosse, Ferreira, Alberto, Cano, Stefan

“…The NEI VFQ-25 has undergone psychometric evaluation in patients with varying ocular conditions and the general population. However, important limitations…”
Get full text

Panretinal Photocoagulation for Proliferative Diabetic Retinopathy by Bressler, Neil M, Beck, Roy W, Ferris, Frederick L

“…Proliferative retinopathy develops in a 55-year-old man with type 2 diabetes. Panretinal photocoagulation, which causes reduced production of VEGF by…”
Get full text

Reproducibility of spectral-domain optical coherence tomography retinal thickness measurements and conversion to equivalent time-domain metrics in diabetic macular edema by Bressler, Susan B, Edwards, Allison R, Chalam, Kakarla V, Bressler, Neil M, Glassman, Adam R, Jaffe, Glenn J, Melia, Michele, Saggau, David D, Plous, Oren Z

“…Understanding measurement variability and relationships between measurements obtained on different optical coherence tomography (OCT) machines is critical for…”
Get more information

Low Luminance Visual Dysfunction as a Predictor of Subsequent Visual Acuity Loss from Geographic Atrophy in Age-Related Macular Degeneration by Sunness, Janet S., MD, Rubin, Gary S., PhD, Broman, Aimee, MS, Applegate, Carol A., COT, Bressler, Neil M., MD, Hawkins, Barbara S., PhD

“…Objective To show that low luminance visual dysfunction is predictive of subsequent visual acuity (VA) loss in eyes with geographic atrophy (GA) resulting from…”
Get full text

Analysis of Macular Edema after Cataract Surgery in Patients with Diabetes Using Optical Coherence Tomography by Kim, Stephen J., MD, Equi, Robert, MD, Bressler, Neil M., MD

“…Objective To assess the incidence or progression of macular edema (ME) after cataract surgery in diabetic patients using optical coherence tomography (OCT) and…”
Get full text

Panretinal Photocoagulation versus Ranibizumab for Proliferative Diabetic Retinopathy: Patient-Centered Outcomes from a Randomized Clinical Trial by Beaulieu, Wesley T, Bressler, Neil M, Melia, Michele, Owsley, Cynthia, Mein, Calvin E, Gross, Jeffrey G, Jampol, Lee M, Glassman, Adam R

“…Abstract Purpose Compare patient-centered outcomes in patients with proliferative diabetic retinopathy (PDR) treated with ranibizumab versus panretinal…”
Get full text

Artificial Intelligence With Deep Learning Technology Looks Into Diabetic Retinopathy Screening by Wong, Tien Yin, Bressler, Neil M

“…Gulshan and colleagues report the use of deep learning technology for diabetic retinopathy screening. Using large data sets of images to first "train" an…”
Get full text