Search Results - "Bresnik, Mark"
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Liposomal Amphotericin B as Initial Therapy for Invasive Mold Infection: A Randomized Trial Comparing a High–Loading Dose Regimen with Standard Dosing (AmBiLoad Trial)
Published in Clinical infectious diseases (15-05-2007)“…Background.Treatment of invasive mold infection in immunocompromised patients remains challenging. Voriconazole has been shown to have efficacy and survival…”
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2516. Development of a de novo Patient-Reported Outcome (PRO) Measure to Assess the Impacts of Disseminated Coccidioidomycosis [Valley Fever] on Patients Living with the Condition
Published in Open forum infectious diseases (27-11-2023)“…Abstract Background Extrapulmonary or disseminated coccidioidomycosis (cocci) is a rare, severe form of fungal disease acquired by inhaling spores of…”
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Pseudomonas aeruginosa Susceptibility Patterns and Associated Clinical Outcomes in People with Cystic Fibrosis following Approval of Aztreonam Lysine for Inhalation
Published in Antimicrobial agents and chemotherapy (17-02-2021)“…The approval of aztreonam lysine for inhalation solution (AZLI) raised concerns that additional antibiotic exposure would potentially affect the susceptibility…”
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ALPINE2: Efficacy and safety of 14-day vs 28-day inhaled aztreonam for Pa eradication in children with cystic fibrosis
Published in Journal of cystic fibrosis (01-01-2024)“…•28-day AZLI is indicated to treat P. aeruginosa (Pa) infection in people with CF.•28-day nebulized treatment eradication protocols can be burdensome for…”
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Randomized comparison of liposomal amphotericin B versus placebo to prevent invasive mycoses in acute lymphoblastic leukaemia
Published in Journal of antimicrobial chemotherapy (01-08-2017)“…To prevent invasive fungal disease (IFD) in adult patients undergoing remission-induction chemotherapy for newly diagnosed acute lymphoblastic leukaemia (ALL)…”
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Inhaled aztreonam lysine vs. inhaled tobramycin in cystic fibrosis: A comparative efficacy trial
Published in Journal of cystic fibrosis (01-03-2013)“…Abstract Background Open-label, parallel-group, international trial comparing aztreonam for inhalation solution (AZLI) and tobramycin nebulizer solution (TNS)…”
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Continuous alternating inhaled antibiotics for chronic pseudomonal infection in cystic fibrosis
Published in Journal of cystic fibrosis (01-11-2016)“…Abstract Background Inhaled antibiotics are standard of care for treating chronic pseudomonal respiratory infections in cystic fibrosis patients, initially…”
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Inhaled aztreonam for chronic Burkholderia infection in cystic fibrosis: A placebo-controlled trial
Published in Journal of cystic fibrosis (01-05-2014)“…Abstract Background Individuals with Burkholderia spp. infection have historically been excluded from efficacy trials of inhaled antibiotics, including…”
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Efficacy outcomes in a randomised trial of liposomal amphotericin B based on revised EORTC/MSG 2008 definitions of invasive mould disease
Published in Mycoses (01-09-2011)“…Summary In 2008, the European Organisation for Research and Treatment of Cancer/Mycoses Study Group (EORTC/MSG) published revised definitions for diagnosing…”
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A safety and feasibility study comparing an intermittent high dose with a daily standard dose of liposomal amphotericin B for persistent neutropenic fever
Published in Journal of medical microbiology (01-11-2009)“…1 Department of Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE 2 Department of Community Medicine, Faculty of…”
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Liposomal Amphotericin B (L-AMB) Is Superior to Amphotericin B Deoxycholate (AmB-d) in Preventing Breakthrough Fungal Infections in Patients with Prolonged Neutropenia and Fever: Results of a Sub-Group Analysis of an Empirical Antifungal Therapy Trial
Published in Blood (16-11-2004)“…In a trial of empirical antifungal therapy in persistently febrile neutropenic patients, L-AMB was shown to be comparable in overall efficacy with…”
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Liposomal Amphotericin B (L-AMB) as Initial Therapy for Invasive Filamentous Fungal Infections (IFFI): A Randomized, Prospective Trial of a High Loading Regimen vs. Standard Dosing (AmBiLoad Trial)
Published in Blood (16-11-2005)“…Background: L-AMB exhibits non-linear pharmacokinetics, with maximal values for Cmax and AUC achieved at a dose of 10 mg/kg/d. Maximal tolerated dose is >15…”
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