Search Results - "Bresciani, Laura G"

Amyloid-Beta Peptide Is Toxic to Neurons In Vivo via Indirect Mechanisms by Walsh, Desmond T., Montero, Rosa M., Bresciani, Laura G., Jen, Angela Y.T., Leclercq, Pascale D., Saunders, Debbie, EL-Amir, Ahmed N., Gbadamoshi, Lukemann, Gentleman, Stephen M., Jen, Ling-Sun

“…We have studied the neurotoxicity of amyloid-beta (Aβ) after a single unilateral intravitreal injection. Within the retina apoptotic cells were seen throughout…”
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Alterations in presenilin 1 processing by amyloid-β peptide in the rat retina by WATTS, Helena R, VINCE, Valerie, WALSH, Desmond T, BRESCIANI, Laura G, GENTLEMAN, Stephen M, JEN, Ling-Sun, ANDERSON, Peter J. B

“…Accumulating evidence indicates that mutations in the presenilin 1 (PS1) gene are responsible for most cases of familial Alzheimer's disease (AD). Although its…”
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Developmental Regulation and Possible Alternative Cleavage of Presenilin 1 in the Rat Retina by Bresciani, Laura G., Walsh, Desmond T., Gentleman, Stephen M., Jen, Ling-Sun

“…Presenilin 1 (PS1) is a multitransmembrane protein well known for being mutated in most cases of familial Alzheimer's disease. Although its pathological effect…”
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Alterations in presenilin 1 processing by amyloid-[beta] peptide in the rat retina by Watts, Helena R, Vince, Valerie, Walsh, Desmond T, Bresciani, Laura G, Gentleman, Stephen M, Ling-Sun, Jen, Anderson, Peter J B

“…Accumulating evidence indicates that mutations in the presenilin 1 (PS1) gene are responsible for most cases of familial Alzheimer's disease (AD). Although its…”
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Upregulation of presenilin 1 after Aβ1–42 injection in a rat retinal model by Bresciani, Laura G., Walsh, Desmond T., Leclercq, Pascale D., Gentleman, Stephen M., Jen, Ling Sun

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Upregulation of presenilin 1 after [formula omitted] injection in a rat retinal model by Bresciani, Laura G., Walsh, Desmond T., Leclercq, Pascale D., Gentleman, Stephen M., Jen, Ling Sun

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Presenilin–1 is Processed into Two Major Cleavage Products in Neuronal Cell Lines by Ward, Robin V., Davis, John B., Gray, Carol W., Barton, Amanda J.L., Bresciani, Laura G., Caivano, Matilde, Murphy, Vivienne F., Duff, Karen, Hutton, Michael, Hardy, John, Roberts, Gareth W., Karran, Eric H.

“…Presenilin 1 (PS–1) has been identified as the protein encoded by the chromosome 14 locus that, when mutated, leads to familial Alzheimer's disease (FAD)…”
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