Search Results - "Brereton, P. S."

Probing the Stoichiometry and Oxidation States of Metal Centers in Iron−Sulfur Proteins Using Electrospray FTICR Mass Spectrometry by Johnson, Keith A, Verhagen, Marc F. J. M, Brereton, Phillip S, Adams, Michael W. W, Amster, I. Jonathan

“…Electrospray ionization (ESI) Fourier transform ion cyclotron resonance mass spectrometry is used to determine the stoichiometry and oxidation states of the…”
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High-throughput production of Pyrococcus furiosus proteins: considerations for metalloproteins by Jenney, Jr, F E, Brereton, P S, Izumi, M, Poole, 2nd, F L, Shah, C, Sugar, F J, Lee, H-S, Adams, M W W

“…Free-living prokaryotic organisms contain all of the proteins required for the basic biochemical processes of life. As part of the Southeastern Collaboratory…”
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Ferredoxin from Pyrococcus furiosus by Kim, C, Brereton, P S, Verhagen, M F, Adams, M W

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Solution NMR Characterization of the Thermodynamics of the Disulfide Bond Orientational Isomerism and Its Effect of Cluster Electronic Properties for the Hyperthermostable Three-Iron Cluster Ferredoxin from the Archaeon Pyrococcus furiosus by Webba da Silva, Mateus, Sham, Simon, Gorst, Carol M, Calzolai, Luigi, Brereton, Philip S, Adams, Michael W. W, La Mar, Gerd N

“…The thermodynamics and dynamics of the Cys21−Cys48 disulfide “S” ⇔ “R” conformational isomerism in the three-iron, single cubane cluster ferredoxin (Fd) from…”
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A Gallium-Substituted Cubane-Type Cluster in Pyrococcus furiosus Ferredoxin by JOHNSON, Keith A., BRERETON, Phillip S., VERHAGEN, Marc F. J. M., CALZOLAI, Luigi, LA MAR, Gerd N., ADAMS, Michael W. W., AMSTER, I. Jonathan

“…Iron-sulfur (Fe-S) clusters are ubiquitous in nature and play a variety of roles including electron transfer and catalysis. One of the best studied is the…”
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Spectroscopic Evidence for a New Type of [Fe3S4] Cluster in a Mutant Form of Pyrococcus furiosus Ferredoxin by Duderstadt, Randall E, Brereton, Phillip S, Adams, Michael W. W, Johnson, Michael K

“…In addition to the more established electron transfer and catalytic roles, there is increasing evidence that Fe-S clusters are intimately involved in…”
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Structure determination of a new protein from backbone-centered NMR data and NMR-assisted structure prediction by Mayer, K. L., Qu, Y., Bansal, S., LeBlond, P. D., Jenney Jr, F. E., Brereton, P. S., Adams, M. W. W., Xu, Y., Prestegard, J. H.

“…Targeting of proteins for structure determination in structural genomic programs often includes the use of threading and fold recognition methods to exclude…”
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Backbone solution structures of proteins using residual dipolar couplings: application to a novel structural genomics target by Valafar, H, Mayer, K L, Bougault, C M, LeBlond, P D, Jenney, Jr, F E, Brereton, P S, Adams, M W W, Prestegard, J H

“…Structural genomics (or proteomics) activities are critically dependent on the availability of high-throughput structure determination methodology. Development…”
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GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant by Cole, Timothy J., Myles, Kathy, Purton, Jared F., Brereton, Phillip S., Solomon, Nicola M., Godfrey, Dale I., Funder, John W.

“…The introduction of a targeted insertion mutation into exon 2 of the gene coding for the glucocorticoid receptor (GR) enabled production of glucocorticoid…”
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Effect of Iron-Sulfur Cluster Environment in Modulating the Thermodynamic Properties and Biological Function of Ferredoxin from Pyrococcus furiosus by Brereton, Phillip S, Verhagen, Marc F. J. M, Zhou, Zhi H, Adams, Michael W. W

“…The ferredoxin (7.5 kDa) of the hyperthermophilic archaeon, Pyrococcus furiosus, contains a single [4Fe-4S]1+,2+ cluster that is coordinated by three Cys and…”
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Effect of Serinate Ligation at Each of the Iron Sites of the [Fe4S4] Cluster of Pyrococcus furiosus Ferredoxin on the Redox, Spectroscopic, and Biological Properties by Brereton, Phillip S, Duderstadt, Randall E, Staples, Christopher R, Johnson, Michael K, Adams, Michael W. W

“…Pyrococcus furiosus ferredoxin (Fd) contains a single [Fe4S4] cluster coordinated by three cysteine (at positions 11, 17, and 56) and one aspartate ligand (at…”
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Backbone solution structures of proteins using residual dipolar couplings: Application to a novel structural genomics target by Valafar, H., Mayer, K. L., Bougault, C. M., LeBlond, P. D., Jenney, F. E., Brereton, P. S., Adams, M. W. W., Prestegard, J. H.

“…Structural genomics (or proteomics) activities are critically dependent on the availability of high-throughput structure determination methodology. Development…”
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A Solution NMR Molecular Model for the Aspartate-Ligated, Cubane Cluster Containing Ferredoxin from the Hyperthermophilic Archeaon Pyrococcus furiosus by Sham, Simon, Calzolai, Luigi, Wang, Peng-Liang, Bren, Kara, Haarklau, Halvard, Brereton, Philip S, Adams, Michael W. W, La Mar, Gerd N

“…A solution molecular model for the conformationally dynamically heterogeneous Pyrococcus furiosus ferredoxin with an intact disulfide bond has been constructed…”
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A pure S=3/2 [Fe 4S 4] + cluster in the A33Y variant of Pyrococcus furiosus ferredoxin by Duderstadt, Randall E, Brereton, Phillip S, Adams, Michael W.W, Johnson, Michael K

“…The properties of the [4Fe-4S] 2+/+ cluster in wild-type and the A33Y variant of Pyrococcus furiosus ferredoxin have been investigated by the combination of…”
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Secondary Structure Extensions in Pyrococcus furiosus Ferredoxin Destabilize the Disulfide Bond Relative to That in Other Hyperthermostable Ferredoxins. Global Consequences for the Disulfide Orientational Heterogeneity by Wang, Peng-Liang, Calzolai, Luigi, Bren, Kara L, Teng, Quincy, Jenney, Francis E, Brereton, Philip S, Howard, James B, Adams, Michael W. W, La Mar, Gerd N

“…The single cubane cluster ferredoxin (Fd) from the hyperthermophilic archaeon Pyrococcus furiosus (Pf) possesses several unique properties when compared even…”
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Comparison of Native and Mutant Proteins Provides a Sequence-Specific Assignment of the Cysteinyl Ligand Proton NMR Resonances in the 2[Fe4S4] Ferredoxin from Clostridium pasteurianum by Scrofani, Sergio D. B, Brereton, Phillip S, Hamer, Amanda M, Lavery, Megan J, McDowall, Sharon G, Vincent, Graham A, Brownlee, Robert T. C, Hoogenraad, Nicholas J, Sadek, Maruse, Wedd, Anthony G

“…A sequence-specific assignment is presented for the eight low-field paramagnetically shifted cysteinyl ligand proton NMR resonances in the 2[Fe4S4] ferredoxin…”
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Investigation of the role of surface residues in the ferredoxin from Clostridium pasteurianum by Brereton, PhillipS, Maher, MeganJ, Tregloan, PeterA, Wedd, AnthonyG

“…Eleven mutant forms of the ferredoxin from Clostridium pasteurianum ( CpFd; 2 Fe 4S 4; 6200 Da) have been isolated in which six surface carboxylates are…”
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Light and Electron Microscopy Localization of the 11β-Hydroxysteroid Dehydrogenase Type I Enzyme in the Rat by Brereton, Phillip S, van Driel, Rosemary R, Suhaimi, Farihah binti Haji, Koyama, Kaori, Dilley, Rod, Krozowski, Zygmunt

“…The 11β-hydroxysteroid dehydrogenase type I enzyme (11βHSD1) converts cortisone to cortisol in humans, and 11-dehydrocorticosterone to corticosterone in…”
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Modification of seedling growth of triticale and barley by seed-applied chlormequat by Naylor, R.E.L. (Aberdeen Univ., Scotland (UK). School of Agriculture), Brereton, P.S, Munro, L

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Light and electron microscopy localization of the 11beta-hydroxysteroid dehydrogenase type I enzyme in the rat by Brereton, P S, van Driel, R R, Suhaimi Fb, Koyama, K, Dilley, R, Krozowski, Z

“…The 11beta-hydroxysteroid dehydrogenase type I enzyme (11betaHSD1) converts cortisone to cortisol in humans, and 11-dehydrocorticosterone to corticosterone in…”
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