Search Results - "Brepoels, Kathleen"
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Elimination of a human T-cell region in staphylokinase by T-cell screening and computer modeling
Published in Thrombosis and haemostasis (01-04-2002)“…Staphylokinase is a potent highly fibrin-selective thrombolytic agent, but it induces a humoral immune response in most treated patients…”
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Pharmacokinetic and thrombolytic properties of cysteine-linked polyethylene glycol derivatives of staphylokinase
Published in Blood (01-02-2000)“…Recombinant staphylokinase (SakSTAR) variants obtained by site-directed substitution with cysteine, in the core (lysine 96 [Lys96], Lys102, Lys109, and/or…”
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Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation
Published in Cell metabolism (01-10-2019)“…Leigh syndrome is a devastating mitochondrial disease for which there are no proven therapies. We previously showed that breathing chronic, continuous hypoxia…”
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Journal Article