Search Results - "Brentzel, H J"

Inhibition of mitochondrial carnitine palmitoyl transferase A in vivo with methyl 2-tetradecylglycidate (methyl palmoxirate) and its relationship to ketonemia and glycemia by Tutwiler, G F, Brentzel, H J, Kiorpes, T C

“…The oral hypoglycemic agent, methyl 2-tetradecylglycidate (Me-TDGA), which inhibits in vitro mitochondrial carnitine palmitoyl transferase A (CPT-A) was used…”
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Phase I clinical and pharmacokinetic trial of brequinar sodium (DUP 785; NSC 368390) by ARTEAGA, C. L, BROWN, T. D, KUHN, J. G, SHEN, H.-S. L, O'ROURKE, T. J, BEOUGHER, K, BRENTZEL, H. J, VON HOFF, D. D, WEISS, G. R

“…Brequinar sodium is a 4-quinolinecarboxylic acid analogue that inhibits dihydroorotate dehydrogenase and subsequent de novo pyrimidine biosynthesis. It has…”
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The role of alcohol dehydrogenase in microsomal ethanol oxidation and the adaptive increase in ethanol metabolism due to chronic treatment with ethanol by Thurman, R G, Brentzel, H J

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Significant pathways of hepatic ethanol metabolism by Thurman, R G, McKenna, W R, Brentzel, Jr, H J, Hesse, S

“…Rat liver microsomes oxidized ethanol two to three times faster than propanol when incubated with either an NADPH- or an H2O2-generating system. In addition,…”
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Common mechanism for the adaptive increase in hepatic ethanol and acetaldehyde metabolism due to chronic pretreatment with ethanol by Thurman, R G, Brentzel, H J, McKenna, W R

“…Perfused livers from ethanol pretreated rats utilized ethanol and acetaldehyde at higher rates than appropriate controls. This adaptive increase in hepatic…”
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Relation of oxidation of long-chain fatty acids to gluconeogenesis in the perfused liver of the guinea pig: effect of 2-tetradecylglycidic acid (McN-3802) by Tutwiler, G F, Brentzel, H J

“…1. The potent, specific inhibitor of long-chain fatty acid oxidation, 2-tetradecylglycidic acid (McN-3802), at 10 microM totally abolished ketogenesis from…”
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Effect of the oral hypoglycemic agent, pirogliride, on gluconeogenesis by Tutwiler, G F, Brentzel, H J

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Effect of the fatty acid oxidation inhibitor 2-tetradecylglycidic acid (TDGA) on glucose and fatty acid oxidation in isolated rat soleus muscle by Tuman, R W, Joseph, J M, Brentzel, H J, Tutwiler, G F

“…1. The effect of 2-tetradecylglycidic acid (TDGA), a potent, specific inhibitor of long-chain fatty acid oxidation, on fatty acid and glucose oxidation by…”
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